Regional Sales Director Jobs in Illinois
Regional Sales Director jobs in Illinois are consistently active, with strong demand concentrated in manufacturing, logistics, financial services, and enterprise technology sectors and openings at every level from high-potential individual contributors stepping into leadership through seasoned senior directors overseeing multi-state territories. Chicago, Peoria, and Naperville anchor the bulk of hiring, and major Illinois employers such as Caterpillar, Abbott, and Zurich North America regularly seek regional sales directors to lead revenue teams across the Midwest. The most in-demand specialties include B2B technology sales, medical device and life sciences sales, and industrial distribution. Find a role that fits below and apply directly.
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Job Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
What you will do
Let’s do this. Let’s change the world. In this vital role, you will lead the regional sales organization for UPLIZNA in Neurology (gMG and NMOSD), translating brand strategy into focused execution and delivering results through a high-performing team.
The Regional Sales Director (RSD) is accountable for the leadership, performance and development of the UPLIZNA Neurology sales organization across the assigned region. This leader will establish regional strategy, create clarity around priorities and expectations, and develop District Managers and field teams to execute with excellence. The RSD will operate as a senior commercial leader and strategic business partner, using market insights, customer understanding and cross-functional collaboration to identify opportunities, remove barriers and drive sustainable performance in a complex rare disease marketplace.
- Lead the region as a business, translating UPLIZNA brand priorities into a focused regional strategy, clear execution imperatives, measurable standards and disciplined operating rhythms.
- Deliver business results through others by equipping District Managers as force multipliers, setting clear performance expectations, using leading indicators to identify opportunities and risks early, and driving timely action and accountability.
- Coach and develop District Managers through a consistent observe, diagnose, practice and follow-up approach that strengthens leadership capability, business acumen, coaching quality, decision-making and representative performance.
- Build and sustain a high-performing, inclusive and compliant culture grounded in Amgen values, patient focus, operational excellence, accountability, scientific integrity and clear, credible leadership communication.
- Attract, select, onboard, retain and develop future-ready talent; establish meaningful development priorities for leaders and maintain strong succession and bench plans for critical roles across the region.
- Synthesize performance data, access dynamics, customer needs, competitive signals and field intelligence to generate decision-ready insights, identify root causes and dynamically adjust regional plans and resources.
- Maintain deep knowledge of gMG and NMOSD, the UPLIZNA clinical profile, the treatment landscape and evolving customer and market dynamics, translating that understanding into relevant regional strategy and field direction.
- Develop strong relationships with key customers and stakeholders and provide visible leadership at priority regional and national congresses, conferences and other strategic customer engagements.
- Lead with an enterprise mindset, appropriately and compliantly orchestrating Marketing, Market Access, Patient Services, Medical, Training, Commercial Operations, HR and other partners around shared brand and business objectives.
- Anticipate, adapt and lead through change by monitoring early signals, clarifying what is changing and why, making thoughtful start-stop trade-offs, and keeping teams focused, aligned and accountable through ambiguity.
- Allocate regional resources, operating expenses and program investments to the highest-priority opportunities, balancing patient impact, business performance, risk and established budget expectations.
- Ensure all regional activities are conducted in accordance with applicable laws, regulations, company policies and Amgen compliance, ethics and safety standards, reinforcing responsible performance and appropriate business conduct.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The Regional Sales Director professional we seek is a strategic, results-oriented people leader with these qualifications.
Basic Qualifications:
Doctorate degree and 4 years of collective account management, sales, marketing and/or commercial experience
OR
Master’s degree and 8 years of collective account management, sales, marketing and/or commercial experience
OR
Bachelor’s degree and 10 years of collective account management, sales, marketing and/or commercial experience
In addition to meeting at least one of the above requirements, candidates must have at least 4 years of experience directly managing people and/or leadership experience leading teams, projects or programs, or directing the allocation of resources. Managerial experience may run concurrently with the required commercial experience referenced above.
Preferred Qualifications:
- Bachelor’s degree required; advanced degree or MBA preferred.
- 5+ years of sales leadership experience, with demonstrated success developing people leaders and delivering business results through multi-level field organizations.
- 10+ years of biotech/pharmaceutical commercial experience; rare disease, neurology, specialty biologic and/or buy-and-bill experience strongly preferred.
- Demonstrated success attracting and developing talent, building succession pipelines, creating healthy high-performance cultures and leading organizations through growth and change.
- Strong insight and strategic agility, including the ability to synthesize multiple data sources and market signals, diagnose business drivers and translate insights into focused regional strategy and resource decisions.
- Proven ability to translate brand priorities into clear execution standards, leading indicators, operating rhythms and timely performance actions.
- Strong executive presence and communication skills, with the ability to simplify complex strategy, inspire followership and influence stakeholders at varying organizational levels.
- Demonstrated enterprise mindset and ability to orchestrate cross-functional partners in a complex matrix environment while maintaining clear decision rights, accountability and compliant ways of working.
- Strong understanding of the U.S. pharmaceutical regulatory and compliance environment.
- Requires approximately 60% travel, including some overnight and weekend commitments.
- Proficient in Microsoft Office.
- Professional, proactive demeanor.
- Strong interpersonal skills.
- Excellent written and verbal communication skills.
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
and make a lasting impact with the Amgen team.
careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
See All 78 Regional Sales Director Jobs in Illinois
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Find Regional Sales Director JobsRegional Sales Director Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Regional Sales Director Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Staffing & Recruiting
- Biotechnology & Pharmaceuticals
What Illinois Employers Look For
The qualifications that appear most often in regional sales director jobs across Illinois.
- Bachelor's degree in business, marketing, or a related field is required
- Five or more years of B2B or enterprise sales experience with demonstrated quota attainment
- Proven leadership experience managing and developing a field sales team
- Deep familiarity with Illinois and Midwest regional markets, customers, and distribution channels
- Proficiency with CRM platforms such as Salesforce for pipeline and performance reporting
- Experience selling into manufacturing, financial services, or healthcare verticals preferred
Regional Sales Director Jobs in Illinois: Frequently Asked Questions
How do you become a regional sales director in Illinois?
Becoming a regional sales director in Illinois typically starts with a bachelor's degree in business, marketing, or a technical field aligned to your target industry, followed by several years building quota-carrying sales experience in Illinois markets. No state-issued license is required for the role itself, but industry credentials such as Certified Professional Sales Leader designation or certifications specific to medical devices or financial products strengthen candidacy significantly with Illinois employers across manufacturing, healthcare, and financial services.
How much do regional sales directors make in Illinois?
Regional sales directors in Illinois earn a median of about $155,280 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $78,760 for the lowest 10% to over $282,890 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire regional sales directors in Illinois?
Employers hiring regional sales directors in Illinois right now include Abbott, Aunt Martha's Health & Wellness, and DaVita, based on current listings on Migrate Mate as of November 2026. Illinois's deep concentration of Fortune 500 headquarters and Midwest regional offices means openings appear across a wide range of industries, from industrial manufacturing and life sciences to enterprise software and insurance.
Which Illinois cities have the most regional sales director jobs?
Chicago, Illinois, and Aurora are the Illinois cities with the most regional sales director openings, driven by Chicago's role as a national corporate headquarters hub and a dense concentration of financial services, technology, and healthcare employers, while Naperville and surrounding collar counties add openings tied to the large enterprise and manufacturing campuses located along the I-88 technology corridor.
Are there remote regional sales director jobs in Illinois?
Yes, and more than many senior roles, since regional sales directors often manage distributed teams and travel to clients rather than sitting in a single office. About 68% of regional sales director openings tied to Illinois are remote or hybrid as of November 2026, reflecting the field-based nature of the work. The most remote-friendly segments tend to be enterprise software, insurance, and financial services sales leadership.
How can I get hired as a regional sales director in Illinois with little or no experience?
The most realistic entry path is moving up from a senior individual contributor or team lead role within an Illinois employer that promotes from within, such as large distributors, manufacturers, or insurance carriers headquartered in the Chicago metro. Targeting associate director or sales manager titles at companies like Grainger or Baxter, building a record of territory growth, and pursuing a Certified Professional Sales Leader credential gives candidates without a formal director title a concrete edge when making the transition.
Where can I find and apply to regional sales director jobs in Illinois?
You can find and apply to regional sales director jobs in Illinois on Migrate Mate, which lists current Illinois openings across industries and locations. Find roles that fit your experience and territory preferences and apply directly to the employers posting them.
See All 78 Regional Sales Director Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
Find Regional Sales Director Jobs