Application Support Specialist Jobs in Missouri

Application Support Specialist jobs in Missouri are consistently active, concentrated in healthcare IT, financial services, and state government technology operations, with openings at every level from junior helpdesk-adjacent roles to senior enterprise support positions. St. Louis, Kansas City, and Jefferson City account for the bulk of hiring, with well-established employers like Centene Corporation, Edward Jones, and Cerner (now Oracle Health) maintaining ongoing demand for application support talent. The most sought-after specialties in Missouri are EHR system support, ERP administration, and customer-facing enterprise software troubleshooting. See the openings below and apply to the ones that match your experience.

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Overview

Open roles9
Top employerJack Henry & Associates
Top cityKansas City, MO
Cities hiring5
Work type83% Remote
Top industryTechnology

Showing 5 of 9+ Application Support Specialist jobs

UMB Financial Corporation
Fraud Payments Application Support Specialist
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UMB Financial Corporation
Added 5d ago
Fraud Payments Application Support Specialist
UMB Financial Corporation
Kansas City, Missouri
Business Analysis
Business Operations
Project Management
$82k - $120k/yr
1,001-5,000

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UMB Financial Corporation
Application Support Specialist (Online Banking)
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UMB Financial Corporation
Added 6d ago
Application Support Specialist (Online Banking)
UMB Financial Corporation
Kansas City, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
$82k - $120k/yr
1,001-5,000

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Jack Henry & Associates
Application Support Analyst III: Complementary Solutions
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Jack Henry & Associates
Added 2w ago
Application Support Analyst III: Complementary Solutions
Jack Henry & Associates
Springfield, Missouri
IT Support
IT Support & Systems Administration
Systems Administration
Technical Program Management
$54k - $70k/yr
Remote (US)
Bachelor's degree
5,001-10,000

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Jack Henry & Associates
Application Support Analyst III: Complementary Solutions
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Jack Henry & Associates
Added 2w ago
Application Support Analyst III: Complementary Solutions
Jack Henry & Associates
Monett, Missouri
Business Analysis
Program Management
Project & Program Management
Project Management
$54k - $70k/yr
Remote (US)
Bachelor's degree
5,001-10,000

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Children's Mercy Hospitals & Clinics
Application Support Sr Engineer
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Children's Mercy Hospitals & Clinics
Added 2w ago
Application Support Sr Engineer
Children's Mercy Hospitals & Clinics
Kansas City, Missouri
Customer Support
IT Support
Technical Product & Program Management
ITIL Certification
5,001-10,000

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See All 9 Application Support Specialist Jobs in Missouri

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Application Support Specialist Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

Kansas City
4 jobs
Springfield
2 jobs
Monett
1 job
St. Louis
1 job
Chesterfield
1 job

Application Support Specialist Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

Jack Henry & Associates
Jack Henry & Associates3 open roles
UMB Financial Corporation
UMB Financial Corporation2 open roles
Dierbergs
Dierbergs1 open role

Top Industries Hiring

  • Technology & Software
  • Electronics & Hardware

What Missouri Employers Look For

The qualifications that appear most often in application support specialist jobs across Missouri.

  • Bachelor's degree in information technology, computer science, or a related field
  • Demonstrated experience supporting enterprise applications such as EHR, ERP, or CRM systems
  • Proficiency in troubleshooting software issues and documenting resolutions in ticketing systems
  • Strong written and verbal communication skills for end-user support and escalation handling
  • Experience working with SQL queries or basic database tools to investigate application issues
  • Familiarity with ITIL frameworks or structured incident and change management processes

Application Support Specialist Jobs in Missouri: Frequently Asked Questions

How do you become a application support specialist in Missouri?

Most Missouri employers expect a bachelor's degree in information technology, computer science, or a related field, though some accept an associate degree combined with substantial hands-on experience. No state-issued license is required to work as an application support specialist in Missouri. Candidates who add vendor or industry certifications such as CompTIA A+, ITIL Foundation, or platform-specific credentials from Microsoft or Salesforce move through hiring pipelines faster with Missouri's major healthcare and financial services employers.

Which companies hire application support specialists in Missouri?

Employers hiring application support specialists in Missouri right now include Jack Henry & Associates, UMB Financial Corporation, and Dierbergs, based on current listings on Migrate Mate as of September 2026. Missouri's concentration of large healthcare systems, financial services firms, and state government technology offices means demand is distributed across both corporate headquarters and regional support centers throughout the state.

Which Missouri cities have the most application support specialist jobs?

Kansas City, Springfield, and Monett have the most application support specialist openings in Missouri. St. Louis leads because of its density of healthcare IT employers and Fortune 500 headquarters, Kansas City follows with strong financial services and logistics technology operations, and Jefferson City draws openings from state government agencies that run large enterprise software environments requiring ongoing application support staff.

Are there remote application support specialist jobs in Missouri?

Yes, and more than most fields, because application support work is largely desk-based and conducted over remote access tools, ticketing platforms, and video calls. About 100% of application support specialist openings tied to Missouri are remote or hybrid as of September 2026, reflecting how well the role translates to distributed work. Tier-2 and Tier-3 support roles that involve system configuration and documentation are the most consistently remote.

How can I get hired as a application support specialist in Missouri with little or no experience?

The most realistic entry path is through a helpdesk or IT support technician role, which Missouri employers like Centene Corporation, SSM Health, and Missouri state agencies routinely post as stepping stones into application support. Community colleges such as St. Louis Community College offer applied IT programs that pair well with CompTIA A+ certification to build a credible foundation. Demonstrating experience with any enterprise software, even through internships or volunteer IT work, makes a candidate stand out when applying to junior application support openings.

Where can I find and apply to application support specialist jobs in Missouri?

You can find and apply to application support specialist jobs in Missouri on Migrate Mate, which lists current Missouri openings updated regularly. Search for roles that match your experience level, preferred location, and industry, then apply directly to the ones that fit. No account creation is needed to view and apply to listings.

See All 9 Application Support Specialist Jobs in Missouri

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