Chief Executive Officer Jobs in Massachusetts
Chief Executive Officer jobs in Massachusetts are open across Boston, Cambridge, and Brookline and other Massachusetts metros, with employers like Beth Israel Lahey Health, TetraScience, and First Help Financial hiring at every experience level. Find a role that fits below and apply directly.
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About TetraScience
TetraScience is the Scientific Data and AI Company and developer of the Tetra OS, the operating system for scientific intelligence. We are fundamentally reimagining and replatforming science for the AI era.
TetraScience’s customers include many of the world’s top biopharmaceutical firms; its growing ecosystem of strategic partners includes NVIDIA, Databricks, Thermo Fisher Scientific, Snowflake, Google, and Microsoft; and its venture capital backers include Boston-based Underscore_VC, global juggernaut Insight Partners, and Impetus Ventures (the CEO’s fund).
In connection with your candidacy, you will be asked to carefully review and internalize "The Tetra Way" and “Unvarnished,” each authored by our CEO, Patrick Grady.
It is impossible to overstate the importance of these essays, and you should take them literally as you decide whether our mission, culture, and expectations are right for you.
Everything you will need to understand about working at TetraScience, and for Patrick, can be found in these writings.
The Opportunity
The Chief of Staff to the CEO is a high-trust, internal and external role for a scientist–business athlete who wants to operate at the center of TetraScience’s relationships with global customers, market-leading partners, and government agencies.
The role requires a fluid schedule, rapid responsiveness, and the ability to travel as needed to support CEO priorities. The role necessitates high clock speed, high bandwidth, insatiable curiosity, authentic humility, and continuous collaboration.
You will help Patrick focus on the few conversations that truly matter, then turn those conversations into structured follow-through that moves alliances, programs, and contracts from idea to impact.
This is an ideal role for someone who enjoys working behind the scenes but at the center of what’s next in scientific data, AI, and policy—equally comfortable in a pharma boardroom, with a hyperscaler account team, or across the table from senior public-sector leaders.
What You Will Do
Amplify the CEO in the market
- Coordinate and support Patrick’s engagement with executives at biopharma companies, major technology partners, and key government agencies and consortia.
- Prepare briefing materials, talking points, and post-meeting summaries that capture objectives, decisions, and next steps for every high-stakes interaction.
Own follow-through on critical relationships
- Turn meeting notes, emails, and Zoom discussions into clear action plans with owners, deadlines, and measures of success—and ensure they are executed.
- Track progress on strategic accounts, alliances, and public-sector initiatives, surfacing risks and opportunities early so Patrick can intervene where he adds the most leverage.
Connect science, business, and policy narratives
- Help craft compelling, concise narratives and materials for senior audiences on themes such as Scientific AI, the value of industrialized scientific data, and sovereign scientific AI.
- Synthesize input from scientists, commercial leaders, policymakers, and investors into options and recommendations that support CEO-level decision-making.
Support a disciplined operating rhythm around the CEO
- Collaborate with Patrick and his executive team to maintain a simple, effective operating cadence that aligns Patrick’s time with TetraScience’s most important priorities.
- Protect his schedule and attention, streamline information flow, and ensure he always walks into critical conversations fully prepared.
Requirements
Who You Are
Scientifically fluent, commercially committed, and outcomes oriented.
- Advanced training in a life sciences discipline (MS or PhD required), plus meaningful exposure to business, strategy, or policy (e.g., consulting, banking, corporate development, VC, or senior operating roles in science-driven organizations).
- Comfortable engaging credibly with R&D leaders, business executives, and public-sector stakeholders on topics that span science, economics, and regulation.
High-judgment operator with range
- Proven ability to manage complex, multi-stakeholder workstreams with a mix of structure, urgency, and calm under pressure, thriving in a fast-paced, often ambiguous environment.
- Willing and able to maintain a flexible schedule, respond quickly to emerging priorities, and travel in support of CEO and company needs.
- Exceptional written and verbal communication skills; you can move seamlessly from a quick email recap to a polished deck or memo for a C-suite or agency audience.
Low-ego, high-standards teammate
- Drawn to doing the unglamorous but essential work—note-taking, follow-ups, logistics, synthesis—that makes high-profile outcomes possible.
- Known for humility, discretion, and trustworthiness; you handle sensitive information and relationships with care.
Aligned with The Tetra Way
- Motivated by a mission with real stakes for patients and society, and energized by working in an elite, high-feedback, high-accountability environment.
- Willing to read, internalize, and live The Tetra Way—rigorous first principles thinking, radical transparency, and extreme ownership as non-negotiables.
Benefits
- Competitive compensation
- Stock options in a VC-backed Series C company
- 100% employer-paid benefits for all eligible employees and immediate family members
- 401(k)
- Unlimited paid time off (PTO)
- Flexible working arrangements
- Company-paid Life Insurance, LTD/STD
See All 13 Chief Executive Officer Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Chief Executive Officer JobsChief Executive Officer Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Chief Executive Officer Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
- Beth Israel Lahey Health4

- TetraScience2

- First Help Financial1

- Heading Home1

- Hri Hospital1

Top Industries Hiring
- Healthcare & Medical Services6
- Biotechnology & Pharmaceuticals3
- Banking & Financial Services2
- Technology & Software2
- Consulting & Professional Services1
What Massachusetts Employers Look For
The qualifications that appear most often in chief executive officer jobs across Massachusetts.
- 10 or more years of senior executive leadership experience including P&L responsibility
- Proven experience leading an organization through growth, restructuring, or strategic transformation
- Strong financial acumen with experience managing budgets and reporting to a board of directors
- Experience developing and executing multi-year organizational strategy
- Excellent communication and stakeholder management skills across executive and board audiences
- Bachelor's degree required, with an MBA or advanced degree preferred by many employers
Chief Executive Officer Jobs in Massachusetts: Frequently Asked Questions
How many chief executive officer jobs are there in Massachusetts?
There are 13+ chief executive officer openings in Massachusetts on Migrate Mate as of June 2026, with the most roles in Boston, Cambridge, and Brookline. New positions post regularly as employers across Massachusetts hire.
Which Massachusetts cities have the most chief executive officer jobs?
Boston, Cambridge, and Brookline have the most chief executive officer openings in Massachusetts right now, with additional roles spread across smaller metros statewide.
Which companies hire chief executive officers in Massachusetts?
Employers hiring chief executive officers in Massachusetts include Beth Israel Lahey Health, TetraScience, and First Help Financial, based on current listings on Migrate Mate as of June 2026.
Are there remote chief executive officer jobs in Massachusetts?
Yes. About 23% of chief executive officer openings tied to Massachusetts are remote or hybrid as of June 2026. The rest are on-site roles based in Massachusetts metros.
How do I apply for chief executive officer jobs in Massachusetts?
You can apply to chief executive officer jobs in Massachusetts directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Massachusetts location, then apply to each one that fits.
See All 13 Chief Executive Officer Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
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