Compliance Officer Jobs in Missouri
Compliance Officer jobs in Missouri are open across Kansas City, St. Louis, and Kirksville and other Missouri metros, with employers like State Street, Northeast Regional Medical Center, and Polsinelli hiring at every experience level. Find a role that fits below and apply directly.
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Hiring Department
The Office of Research and Innovation at the University of Missouri-Kansas City.
Job Description
Reporting directly to the Vice Chancellor for Research and Innovation (VCRI), the Research Compliance Officer – Partnerships serves as the division’s dedicated compliance authority for external collaborations. This role bridges the gap between complex federal regulations and the speed required for modern innovation, functioning as the primary Point of Contact (POC) for hospital affiliates and industry sponsors. The Officer is responsible for performing independent, substantive reviews of exempt and expedited protocols (IRB/IACUC), managing the lifecycle of reliance agreements, and driving operational efficiency. By working directly under the VCRI’s strategic guidance and in tandem with Compliance Managers, this role ensures that clinical trials and cooperative research projects are reviewed with rigor and launched with velocity, minimizing administrative burden while maintaining the highest standards of research integrity.
Primary Responsibilities:
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Partner Point of Contact (POC) & Reliance Management: Serve as the dedicated Compliance POC and primary operational link between the Office of Research and Innovation and external partners (including hospital affiliates and corporate sponsors), managing the administrative workflow of IRB reliance agreements and cooperative research authorizations.
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Independent Regulatory Review & Determination: Perform comprehensive, substantive reviews of research protocols (specifically Exempt and Expedited categories) to evaluate ethical design and regulatory adherence; independently issue determinations, request stipulations, and approve protocols in accordance with federal regulations (Common Rule, FDA) and UMKC policy.
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Clinical Trial Acceleration: Expedite the compliance phase for industry-sponsored clinical trials by performing pre-reviews of "straightforward" (exempt and expedited) human subjects’ protocols, ensuring rapid turnaround times to meet sponsor deadlines.
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Integrated Compliance Review (IRB/IACUC): Coordinate the administrative intake and review process for both Human Subjects (IRB) and Animal Care (IACUC) protocols involving external collaborators, ensuring seamless alignment between UMKC policies and partner institution requirements.
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Streamlined "Straightforward" Approvals: Independently manage a portfolio of low-risk, exempt, and expedited reviews, acting as a fast-track channel for non-committee approvals to keep partnership projects moving efficiently.
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Cross-Domain Integrity Support: Work in tandem with Compliance Managers to verify ancillary compliance requirements—such as Biosafety (IBC) and Conflict of Interest (COI)—ensuring that complex, multi-institutional projects meet all federal and university standards before launch.
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Regulatory Documentation & Audit Readiness: Maintain meticulous records of inter-institutional agreements (IIAs) and single IRB (sIRB) documentation, ensuring the university remains audit-ready for federal agencies (FDA, OHRP, OLAW) and industry sponsors.
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Operational Efficiency & Process Optimization: Proactively identify administrative bottlenecks and implement solutions to achieve maximum efficiency in the compliance pipeline, acting as a dedicated problem-solver to ensure a frictionless experience for clinical investigators and industry partners.
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External Partner Training and Onboarding: Develop and deliver training orientation sessions to the external teams and/or PIs, and create partner-specific guidance documents.
The Ideal Candidate
We are looking for a professional who thrives in a fast-paced environment and possesses:
- The ability to perform independent, substantive reviews of exempt and expedited protocols (IRB/IACUC).
- A proactive mindset to identify administrative bottlenecks and implement solutions that ensure a frictionless experience for clinical investigators.
- The expertise to balance federal regulatory requirements with the strategic goals of the Division of Research and Innovation.
NOTE: This position may include travel.
Minimum Qualifications
A Bachelor's degree and at least 5 years of experience from which comparable knowledge and skills can be acquired is necessary.
Preferred Qualifications
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A bachelor’s degree from an accredited institution in a field related to research administration, compliance, or regulatory oversight is required. Appropriate areas of study may include, but are not limited to, public administration, health administration, public health, biomedical or life sciences, social or behavioral sciences, regulatory affairs, law, ethics, compliance, healthcare management, or a closely related field.
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3–5 years of experience in research administration, compliance, Institutional Review Board and Institutional Animal Care and Use Committee support, regulatory affairs, human subjects research (via Institutional Review Board), animal research compliance (via Institutional Animal Care and Use Committee), and/or research integrity, regulatory compliance, or audit functions is strongly preferred.
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Experience in academic medical centers, universities, government-funded research, or clinical research organizations is preferred.
Anticipated Hiring Range
The anticipated hiring range for this position has been established as $69,097.60 to $80,000.00 annually.
Salary is determined by a variety of factors, including but not limited to, the individual’s particular combination of education, skills, and experience, as well as organizational requirements.
Your total compensation goes beyond the number on your paycheck. The University of Missouri provides generous leave, health plans, and retirement contributions that add to your bottom line.
Grade: GGS 12
University Title: ASSOCIATE DIRECTOR COMPLIANCE
To review the University of Missouri’s Staff Compensation Structure you can view the Job Code detail page. Internal applicants can determine their university title by accessing the Talent Profile tile in myHR.
Application Deadline
Job posting will remain open until filled.
Community Information
Kansas City offers the best of both worlds—a vibrant, urban community with Midwestern appeal. The city’s rich history and its modern-day, innovative thinking come together to create an eclectic group of neighborhoods that offer a little something for everyone. From thriving arts districts, an energetic downtown nightlife, casual to upscale shopping and champion sports teams, you will have no problem making yourself at home. Of course, one of Kansas City’s biggest claims to fame is its food, especially its world-famous barbecue. Foodies will delight in the culinary scene found throughout the city. Ranging from award-winning chefs to cozy pizza joints, Kansas City definitely is not lacking any flavor.
UMKC’s campuses are conveniently nestled in the middle of all the action. Volker Campus is just minutes from the legendary Country Club Plaza, perfect for shopping or restaurants for lunch or after-work happy hours. Surrounded by hip neighborhoods and eateries, the Health Sciences Campus is located downtown near University Health Truman Medical Center and Children’s Mercy Hospital.
UMKC is proud to be “Kansas City’s university,” and the campus and its people celebrate all the characteristics of the surrounding community. To learn more about life in Kansas City and find more resources, visit VisitKC.com.
Benefit Eligibility
This position is eligible for University benefits. As part of your total compensation, the University offers a comprehensive benefits package, including medical, dental and vision plans, retirement, paid time off, short- and long-term disability, paid parental leave, paid caregiver leave, and educational fee discounts for all four UM System campuses. For additional information on University benefits, please visit the Faculty & Staff Benefits website at https://www.umsystem.edu/totalrewards/benefits.
Equal Employment Opportunity
The University of Missouri is an Equal Opportunity Employer.
To request ADA accommodations, please call the Office of Equity & Title IX at 816-235-6910.
See All 24 Compliance Officer Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find Compliance Officer JobsCompliance Officer Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Compliance Officer Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
- State Street5

- Northeast Regional Medical Center2

- Polsinelli2

- Stifel2

- Abbott1

Top Industries Hiring
- Banking & Financial Services6
- Law & Legal Services5
- Education4
- Healthcare & Medical Services3
- Investment & Asset Management3
What Missouri Employers Look For
The qualifications that appear most often in compliance officer jobs across Missouri.
- Bachelor's degree in finance, law, business, or a related field
- Three or more years of experience in regulatory compliance or audit
- Working knowledge of relevant regulations such as SOX, HIPAA, BSA, or GDPR
- Professional certification such as CCEP, CRCM, CAMS, or CHC preferred
- Experience developing, implementing, or auditing compliance programs and policies
- Strong written communication skills for policy documentation and regulatory reporting
Compliance Officer Jobs in Missouri: Frequently Asked Questions
How many compliance officer jobs are there in Missouri?
There are 24+ compliance officer openings in Missouri on Migrate Mate as of June 2026, with the most roles in Kansas City, St. Louis, and Kirksville. New positions post regularly as employers across Missouri hire.
How much do compliance officers make in Missouri?
Compliance officers in Missouri earn a median of about $67,270 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $44,060 for the lowest 10% to over $118,850 for the top 10%. Pay rises with experience, specialty, and employer.
Which Missouri cities have the most compliance officer jobs?
Kansas City, St. Louis, and Kirksville have the most compliance officer openings in Missouri right now, with additional roles spread across smaller metros statewide.
Which companies hire compliance officers in Missouri?
Employers hiring compliance officers in Missouri include State Street, Northeast Regional Medical Center, and Polsinelli, based on current listings on Migrate Mate as of June 2026.
Are there remote compliance officer jobs in Missouri?
Yes. About 17% of compliance officer openings tied to Missouri are remote or hybrid as of June 2026. The rest are on-site roles based in Missouri metros.
How do I apply for compliance officer jobs in Missouri?
You can apply to compliance officer jobs in Missouri directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Missouri location, then apply to each one that fits.
See All 24 Compliance Officer Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find Compliance Officer Jobs