Nurse Practitioner Or Physician Assistant Jobs in Minnesota

Nurse Practitioner Or Physician Assistant jobs in Minnesota are concentrated in health systems, primary care networks, and specialty clinics, with steady demand at every level from new graduates to experienced clinicians. The heaviest hiring is in the Twin Cities metro, Rochester, and Duluth, where established employers like Mayo Clinic, M Health Fairview, and Allina Health maintain large and ongoing needs. The most in-demand specialties include family medicine, urgent care, and orthopedics. See the openings below and apply to the ones that match your experience.

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Overview

Open roles109+
Top employerMayo Clinic
Top cityMinnesota
Cities hiring45
Work type62% On-site
Top industryHealthcare

Showing 5 of 109+ Nurse Practitioner Or Physician Assistant jobs

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Nurse Practitioner or Physician Assistant | Acute Care
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Added 1d ago
Nurse Practitioner or Physician Assistant | Acute Care
Avera Marshall
Marshall, Minnesota
Customer Service
Customer Support
Hospitality & Guest Services
$121k - $157k/yr

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Mayo Clinic
Nurse Practitioner or Physician Assistant - Hematology Chronic Lymphocytic Leukemia
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Mayo Clinic
Added 1d ago
Nurse Practitioner or Physician Assistant - Hematology Chronic Lymphocytic Leukemia
Mayo Clinic
Rochester, Minnesota
Clinical Trials
Healthcare Administration
Nursing
Patient Services & Wellbeing
$120k.4 - $167k.59/yr
On-Site
BLS Certification
10,000+

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North Memorial Health
Trauma/Surgical Critical Care Advanced Practice Provider (Physician Assistant or Nurse Practitioner), 7/70, North Memorial Health - Robbinsdale Hospital
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North Memorial Health
Added 2d ago
Trauma/Surgical Critical Care Advanced Practice Provider (Physician Assistant or Nurse Practitioner), 7/70, North Memorial Health - Robbinsdale Hospital
North Memorial Health
Robbinsdale, Minnesota
Healthcare Administration
Nursing
Patient Services & Wellbeing
$136k - $164k/yr
On-Site
5,001-10,000

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Sanford Health
APP – Physician Assistant or Nurse Practitioner | Family Medicine- Bemidji/Cass Lake
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Sanford Health
Added 5d ago
APP – Physician Assistant or Nurse Practitioner | Family Medicine- Bemidji/Cass Lake
Sanford Health
Cass Lake, Minnesota
Clinical Support
Healthcare Administration
Medical Specialists
Doctoral degree
10,000+

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University of Minnesota
Psychiatric Nurse Practitioner or Psychiatric Physician Assistant, Boynton Health
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University of Minnesota
Added 5d ago
Psychiatric Nurse Practitioner or Psychiatric Physician Assistant, Boynton Health
University of Minnesota
Minneapolis, Minnesota
Clinical Support
Healthcare Administration
Mental & Behavioral Health
10,000+

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Nurse Practitioner Or Physician Assistant Jobs by City in Minnesota

Where Minnesota roles are concentrated, by current openings.

Saint Cloud
10 jobs
Rochester
8 jobs
Minneapolis
8 jobs
Mankato
6 jobs
Bemidji
5 jobs
Robbinsdale
4 jobs
Olivia
3 jobs
Willmar
3 jobs
New Ulm
2 jobs

Nurse Practitioner Or Physician Assistant Job Market in Minnesota

A snapshot from current Minnesota openings, updated as new roles post.

Who's Hiring

  • Mayo Clinic
    Mayo Clinic15
  • Signify Health
    Signify Health15
  • CentraCare
    CentraCare14
  • Sanford Health
    Sanford Health14
  • Medcor
    Medcor8

Top Industries Hiring

  • Healthcare & Medical Services25
  • Education9
  • Technology & Software2
  • Non-Profit & Social Services2
  • Insurance1

What Minnesota Employers Look For

The qualifications that appear most often in nurse practitioner or physician assistant jobs across Minnesota.

  • Active Minnesota nurse practitioner or physician assistant license issued by the Minnesota Board of Medical Practice
  • Graduate degree from an accredited NP or PA program recognized by Minnesota licensing standards
  • National certification such as NCCPA, AANP, or ANCC appropriate to specialty and role
  • Current DEA registration and ability to prescribe medications under Minnesota collaborative practice rules
  • Minimum clinical experience in a relevant specialty such as family medicine, urgent care, or orthopedics
  • Basic Life Support and Advanced Cardiovascular Life Support certifications maintained and current

Nurse Practitioner Or Physician Assistant Jobs in Minnesota: Frequently Asked Questions

How do you become a nurse practitioner or physician assistant in Minnesota?

To practice in Minnesota, you must obtain a license from the Minnesota Board of Medical Practice, which oversees both nurse practitioners and physician assistants in the state. Nurse practitioners must hold a graduate-level nursing degree and national certification through a body such as AANP or ANCC. Physician assistants must complete an accredited PA program and pass the PANCE. Both roles require a collaborative practice agreement with a supervising physician under Minnesota law.

Which companies hire nurse practitioner or physician assistants in Minnesota?

Employers hiring nurse practitioner or physician assistants in Minnesota right now include Mayo Clinic, Signify Health, and CentraCare, based on current listings on Migrate Mate as of August 2026. Minnesota's large integrated health systems and multispecialty group practices generate the most consistent openings across the state.

Which Minnesota cities have the most nurse practitioner or physician assistant jobs?

Minnesota, Saint Cloud, and Rochester have the most nurse practitioner or physician assistant openings in Minnesota. The Twin Cities metro drives the highest volume because of its dense concentration of hospital systems and specialty clinics, while Rochester's openings are heavily shaped by Mayo Clinic's scale, and Duluth anchors demand for the northeastern region through Essentia Health and St. Luke's.

Are there remote nurse practitioner or physician assistant jobs in Minnesota?

Yes, but they're rare. Most nurse practitioner and physician assistant roles require direct patient contact, which limits remote work by nature. About 38% of nurse practitioner or physician assistant openings tied to Minnesota are remote or hybrid as of August 2026, and those positions are most often in telehealth triage, chronic disease management, or utilization review rather than traditional clinical practice.

How can I get hired as a nurse practitioner or physician assistant in Minnesota with little or no experience?

The most realistic entry path is applying to new-graduate residency or fellowship programs offered by large Minnesota health systems such as Mayo Clinic, Allina Health, and M Health Fairview, which run structured transition-to-practice programs specifically for new NPs and PAs. Candidates who already hold a Minnesota license and national certification are at a clear advantage. Lateral moves from registered nursing, medical assisting, or emergency medicine technician roles into PA or NP support positions can also build the clinical hours that strengthen a first application.

Where can I find and apply to nurse practitioner or physician assistant jobs in Minnesota?

You can find and apply to nurse practitioner or physician assistant jobs in Minnesota on Migrate Mate, which lists current openings from employers actively hiring in the state. Search the listings to find roles that match your specialty, experience level, and preferred location, then apply directly to the ones that fit.

See All 109+ Nurse Practitioner Or Physician Assistant Jobs in Minnesota

Find roles in Minnesota that match your experience and apply in just a few clicks.

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