Nurse Practitioner Or Physician Assistant Jobs in Minnesota

Nurse Practitioner Or Physician Assistant jobs in Minnesota are concentrated in health systems, primary care networks, and specialty clinics, with steady demand at every level from new graduates to experienced clinicians. The heaviest hiring is in the Twin Cities metro, Rochester, and Duluth, where established employers like Mayo Clinic, M Health Fairview, and Allina Health maintain large and ongoing needs. The most in-demand specialties include family medicine, urgent care, and orthopedics. See the openings below and apply to the ones that match your experience.

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Overview

Open roles120+
Top employerMayo Clinic
Top cityRochester, MN
Cities hiring47
Work type60% On-site
Top industryHealthcare

Showing 5 of 120+ Nurse Practitioner Or Physician Assistant jobs

Nurse Practitioner or Physician Assistant - Cardiology
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Nurse Practitioner or Physician Assistant - Cardiology
Allina Health
Baxter, Minnesota
Healthcare Administration
Patient Services & Wellbeing
Physicians
$56.48 - $78.15/hr
Master's degree
10,000+

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Nurse Practitioner or Physician Assistant - Critical Care
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Nurse Practitioner or Physician Assistant - Critical Care
University of Minnesota Physicians
Edina, Minnesota
Healthcare Administration
Nursing
Patient Services & Wellbeing
$137k - $174k/yr
1,001-5,000

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Nurse Practitioner or Physician Assistant - Nephrology
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Nurse Practitioner or Physician Assistant - Nephrology
University of Minnesota Physicians
Minneapolis, Minnesota
Healthcare Administration
Patient Services & Wellbeing
Physicians
$131k - $162k/yr
1,001-5,000

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Nurse Practitioner (NP) or Physician Assistant (PA) - Chatfield Family Medicine
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Added 4d ago
Nurse Practitioner (NP) or Physician Assistant (PA) - Chatfield Family Medicine
Olmsted Medical Center
Chatfield, Minnesota
Clinical Support
Healthcare Administration
Medical Specialists
$56.17 - $84.25/hr
Doctoral degree
1,001-5,000

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Hematology/Oncology Physician Assistant or Nurse Practitioner
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Added 5d ago
Hematology/Oncology Physician Assistant or Nurse Practitioner
Allina Health
Minneapolis, Minnesota
Customer Service
Healthcare Administration
Human Resources
$135k - $164k/yr
BLS Certification
10,000+

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Nurse Practitioner Or Physician Assistant Jobs by City in Minnesota

Where Minnesota roles are concentrated, by current openings.

Rochester
23 jobs
Minneapolis
15 jobs
Saint Cloud
7 jobs
Bemidji
6 jobs
Edina
3 jobs
Willmar
3 jobs
Coon Rapids
3 jobs
Robbinsdale
3 jobs
Olivia
2 jobs

Nurse Practitioner Or Physician Assistant Job Market in Minnesota

A snapshot from current Minnesota openings, updated as new roles post.

Who's Hiring

  • Mayo Clinic20
  • Allina Health13
  • CentraCare11
  • Signify Health11
  • Sanford Health10

Top Industries Hiring

  • Healthcare & Medical Services16
  • Education3
  • Technology & Software3
  • Insurance2
  • Biotechnology & Pharmaceuticals1

What Minnesota Employers Look For

The qualifications that appear most often in nurse practitioner or physician assistant jobs across Minnesota.

  • Active Minnesota nurse practitioner or physician assistant license issued by the Minnesota Board of Medical Practice
  • Graduate degree from an accredited NP or PA program recognized by Minnesota licensing standards
  • National certification such as NCCPA, AANP, or ANCC appropriate to specialty and role
  • Current DEA registration and ability to prescribe medications under Minnesota collaborative practice rules
  • Minimum clinical experience in a relevant specialty such as family medicine, urgent care, or orthopedics
  • Basic Life Support and Advanced Cardiovascular Life Support certifications maintained and current

Nurse Practitioner Or Physician Assistant Jobs in Minnesota: Frequently Asked Questions

How do you become a nurse practitioner or physician assistant in Minnesota?

To practice in Minnesota, you must obtain a license from the Minnesota Board of Medical Practice, which oversees both nurse practitioners and physician assistants in the state. Nurse practitioners must hold a graduate-level nursing degree and national certification through a body such as AANP or ANCC. Physician assistants must complete an accredited PA program and pass the PANCE. Both roles require a collaborative practice agreement with a supervising physician under Minnesota law.

Which companies hire nurse practitioner or physician assistants in Minnesota?

Employers hiring nurse practitioner or physician assistants in Minnesota right now include Mayo Clinic, Allina Health, and CentraCare, based on current listings on Migrate Mate as of October 2026. Minnesota's large integrated health systems and multispecialty group practices generate the most consistent openings across the state.

Which Minnesota cities have the most nurse practitioner or physician assistant jobs?

Rochester, Minneapolis, and Minnesota have the most nurse practitioner or physician assistant openings in Minnesota. The Twin Cities metro drives the highest volume because of its dense concentration of hospital systems and specialty clinics, while Rochester's openings are heavily shaped by Mayo Clinic's scale, and Duluth anchors demand for the northeastern region through Essentia Health and St. Luke's.

Are there remote nurse practitioner or physician assistant jobs in Minnesota?

Yes, but they're rare. Most nurse practitioner and physician assistant roles require direct patient contact, which limits remote work by nature. About 40% of nurse practitioner or physician assistant openings tied to Minnesota are remote or hybrid as of October 2026, and those positions are most often in telehealth triage, chronic disease management, or utilization review rather than traditional clinical practice.

How can I get hired as a nurse practitioner or physician assistant in Minnesota with little or no experience?

The most realistic entry path is applying to new-graduate residency or fellowship programs offered by large Minnesota health systems such as Mayo Clinic, Allina Health, and M Health Fairview, which run structured transition-to-practice programs specifically for new NPs and PAs. Candidates who already hold a Minnesota license and national certification are at a clear advantage. Lateral moves from registered nursing, medical assisting, or emergency medicine technician roles into PA or NP support positions can also build the clinical hours that strengthen a first application.

Where can I find and apply to nurse practitioner or physician assistant jobs in Minnesota?

You can find and apply to nurse practitioner or physician assistant jobs in Minnesota on Migrate Mate, which lists current openings from employers actively hiring in the state. Search the listings to find roles that match your specialty, experience level, and preferred location, then apply directly to the ones that fit.

See All 120+ Nurse Practitioner Or Physician Assistant Jobs in Minnesota

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