Center Manager Jobs in South Carolina

Center Manager jobs in South Carolina are consistently in demand, with strong hiring across healthcare systems, childcare and early education networks, distribution and logistics operations, and workforce development organizations at levels from entry-level site coordinator to senior multi-site director. The largest concentrations of openings are in Columbia, Charleston, and Greenville, where employers such as Prisma Health, Bright Horizons, and Amazon have lasting, significant footprints in the state. Operations-focused center managers and those with backgrounds in healthcare clinic management or early childhood program administration are among the most sought-after candidates right now. Find a role that fits below and apply directly.

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Overview

Open roles57
Top employerFifth Third Bank
Top cityGreenville, SC
Cities hiring27
Work type75% On-site
Top industryConstruction

Showing 4 of 57+ Center Manager jobs

QXO
Commercial Sales Center Manager
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QXO
Added 1d ago
Commercial Sales Center Manager
QXO
Columbia, South Carolina
Account Management
Business Development
Sales
High school diploma or GED
10,000+

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Target
Operations Manager - Regional Distribution Center - Lugoff, SC
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Target
Added 2d ago
Operations Manager - Regional Distribution Center - Lugoff, SC
Target
Lugoff, South Carolina
Customer Service
Retail Banking & Branch Management
Sales
$73k - $132k/yr
Bachelor's degree
10,000+

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Google
Data Center Operations Manager, Global Server Ops, Hardware Operations
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Google
Added 2d ago
Data Center Operations Manager, Global Server Ops, Hardware Operations
Google
Moncks Corner, South Carolina
Cloud Engineering
Data Engineering
IT Support
$122k - $173k/yr
Bachelor's degree
10,000+

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Grifols
Center Manager
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Grifols
Added 2d ago
Center Manager
Grifols
Rock Hill, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Public Health
Bachelor's degree in finance
10,000+

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See All 57 Center Manager Jobs in South Carolina

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Center Manager Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Greenville
12 jobs
Columbia
6 jobs
North Charleston
4 jobs
Rock Hill
3 jobs
Summerville
3 jobs
Myrtle Beach
3 jobs
York
2 jobs
Florence
2 jobs
Orangeburg
2 jobs

Center Manager Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

Fifth Third Bank
Fifth Third Bank6 open roles
Food Lion
Food Lion5 open roles
CBRE
CBRE4 open roles

Top Industries Hiring

  • Construction & Real Estate
  • Investment & Asset Management
  • Agriculture & Farming
  • Technology & Software
  • Artificial Intelligence

What South Carolina Employers Look For

The qualifications that appear most often in center manager jobs across South Carolina.

  • Bachelor's degree in business administration, education, healthcare management, or a related field
  • Minimum three to five years of supervisory or program management experience in a center environment
  • Demonstrated ability to manage budgets, staffing schedules, and daily center operations independently
  • Experience with compliance reporting, quality assurance, or accreditation standards relevant to the center type
  • Strong written and verbal communication skills for staff oversight, family engagement, and reporting to leadership
  • Proficiency with operations software, scheduling platforms, or center management information systems

Center Manager Jobs in South Carolina: Frequently Asked Questions

How do you become a center manager in South Carolina?

The path depends on the center type. For childcare center directors, South Carolina requires a director credential through the South Carolina Department of Social Services, which sets education and experience minimums tied to the center's license level. Healthcare clinic managers typically need a relevant clinical or administrative degree and may pursue credentials through the Medical Group Management Association. For distribution or workforce center roles, no state license applies, but a bachelor's degree and demonstrated operations experience are standard hiring requirements across South Carolina employers.

Which companies hire center managers in South Carolina?

South Carolina center manager roles are posted by Fifth Third Bank, Food Lion, and CBRE and others right now, based on current listings on Migrate Mate as of August 2026. South Carolina's mix of major health systems, national childcare networks, and large logistics operations means hiring is spread across multiple sectors rather than concentrated in a single industry.

Which South Carolina cities have the most center manager jobs?

Greenville, Columbia, and North Charleston have the most center manager openings in South Carolina. Columbia leads because it is home to state government agencies, major hospital systems like Prisma Health and MUSC Health affiliates, and a large university presence, while Charleston's growing healthcare and hospitality sectors and Greenville's expanding manufacturing and corporate base drive steady demand in those metros.

Are there remote center manager jobs in South Carolina?

Yes, but they're rare. Center manager roles are fundamentally on-site positions responsible for day-to-day staff supervision, facility oversight, and in-person service delivery, so full remote arrangements are uncommon by nature. About 25% of center manager openings tied to South Carolina are remote or hybrid as of August 2026, and those are most likely to be administrative, multi-site oversight, or quality assurance roles where direct physical presence at a single location is not required every day.

How can I get hired as a center manager in South Carolina with little or no experience?

The most realistic entry path is to move into a center manager role from a lead teacher, shift supervisor, medical office coordinator, or assistant director position within the same organization. In South Carolina, large childcare operators and healthcare networks such as Prisma Health regularly promote internally from these roles. Earning the South Carolina DSS director credential or an entry-level healthcare administration certificate while in a support role signals readiness to hiring managers. Applying to assistant center manager or associate director postings at multi-site operators in Columbia and Greenville is the most direct route when you lack full management experience.

Where can I find and apply to center manager jobs in South Carolina?

You can find and apply to center manager jobs in South Carolina on Migrate Mate, which lists current openings from employers actively hiring in the state. Search the listings, find roles that match your experience and location, and apply directly to the ones that fit.

See All 57 Center Manager Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Center Manager Jobs