Clinical Manager Jobs in California
Clinical Manager jobs in California are among the most active in the country, concentrated in hospital systems, outpatient networks, behavioral health, and home health agencies, with openings at every level from entry-level coordinator through senior director. The largest hiring markets are Los Angeles, San Francisco, and San Diego, where established employers like Kaiser Permanente, Sutter Health, and Dignity Health maintain deep clinical management teams. Demand is strongest in behavioral health program management, care coordination, and ambulatory care operations. Find a role that fits below and apply directly.
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Showing 5 of 373+ Clinical Manager jobs
Work Schedule
Standard (Mon-Fri)Environmental Conditions
OfficeJob Description
Join Us as Manager Clinical Operations – Make an Impact at the Forefront of Innovation
We have successfully supported the top 50 pharmaceutical companies and more than 750 biotechs, spanning 2,700 clinical trials across 100+ countries in the last 5 years.
As an FSP Manager Clinical Operations, you will oversee, train, resource, coach and performance manage a team, which may be inclusive of various clinical operations focused staff. You will focus on end results using metrics and key performance indicators to lead performance. You will act as point-of-escalation regarding performance concerns and training needs to ensure adherence to the company's SOPs and WPDs. You will also work in collaboration with the leadership team for resourcing needs. In this role, you will be dedicated to one sponsor in our FSP environment.
What You’ll Do:
- Manages staff, providing coaching, mentorship and work direction.
- Conducts regular performance appraisals and career discussions with staff. Facilitates employee career development. Interviews, recruits and selects staff.
- Manages and conducts induction/orientation programs for all new employees, ensuring their smooth assimilation into the company.
- Ensures all staff CVs, training records, position profiles and experience profiles are complete and up-to-date. Ensures timeliness and accuracy of timesheets and expense reports.
- Supports allocation activities per the local resourcing process. Supports activities of project leads/functional leads to optimize the operational running of projects. Raises appropriately any issues which may impact project deliverables.
- Delivers training on Working Practice Documents (WPDs) and Standard Operating Procedures (SOPs), local requirements and any other subjects that impact on clinical operations. Identifies training gaps and ensures that training requirements are met. May contribute to development of training programs, where appropriate.
- Assures adherence to good ethical and regulatory standards.
- Alerts management to quality issues, request QA audits as appropriate, and facilitate client and internal quality assurance audits as required.
- Handles and reviews systems (e.g. Activate, CTMS, Preclarus, Clarity) to evaluate employee and project metrics, KPIs and general project status.
- Evaluates work of staff, including conducting PAVs (either remote or on-site) to thoroughly evaluate the employee monitoring skills and project conduction when applicable.
- Participates in process improvement/development initiatives.
- Ensures understanding and facilitation of the risk-based monitoring approach.
- May provide input into bids and contribute to the procurement of new business where required.
- Collaborates with clinical operations senior management and executive staff on strategic planning and business development as required.
- May lead or contribute to initiatives that enhance the department's performance or lead to process improvement across the company.
Education and Experience Requirements:
- Bachelor's degree or equivalent and relevant formal academic / vocational qualifications
- Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 0 to 5 years).
- 1+ year of leadership responsibility
- In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
Knowledge, Skills and Abilities:
- Advanced mentoring/leadership/supervisory skills
- Excellent clinical trials monitoring skills; Remote and on-site
- Demonstrated understanding of or ability to learn the company’s SOPs, WPDs, and relevant regulations (e.g. ICH/GCP, FDA guidelines)
- Demonstrated ability to evaluate medical research data
- Strong organizational and negotiation skills
- Strong attention to detail
- Advanced written and oral communication skills
- Good knowledge of English language and grammar
- Demonstrated use of computer to include data entry, archival and retrieval
- Ability to travel as needed
- Excellent teammate with team building skills
- Excellent interpersonal and conflict resolution skills
- Advanced ability to utilize problem-solving techniques applicable to constantly changing environment
- Solid knowledge of medical/therapeutic areas and medical terminology
Why Join Us?
When you join Thermo Fisher Scientific, you become part of a global team that values passion, innovation, and a commitment to scientific excellence. You’ll work in an environment where collaboration and development are part of the everyday experience—and where your contributions truly make a difference.
Apply today to help us deliver tomorrow’s breakthroughs.
Compensation and Benefits
The salary range estimated for this position based in California is $115,000.00–$180,000.00.This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
Work Schedule
Standard (Mon-Fri)Environmental Conditions
OfficeJob Description
Join Us as Manager Clinical Operations – Make an Impact at the Forefront of Innovation
We have successfully supported the top 50 pharmaceutical companies and more than 750 biotechs, spanning 2,700 clinical trials across 100+ countries in the last 5 years.
As an FSP Manager Clinical Operations, you will oversee, train, resource, coach and performance manage a team, which may be inclusive of various clinical operations focused staff. You will focus on end results using metrics and key performance indicators to lead performance. You will act as point-of-escalation regarding performance concerns and training needs to ensure adherence to the company's SOPs and WPDs. You will also work in collaboration with the leadership team for resourcing needs. In this role, you will be dedicated to one sponsor in our FSP environment.
What You’ll Do:
- Manages staff, providing coaching, mentorship and work direction.
- Conducts regular performance appraisals and career discussions with staff. Facilitates employee career development. Interviews, recruits and selects staff.
- Manages and conducts induction/orientation programs for all new employees, ensuring their smooth assimilation into the company.
- Ensures all staff CVs, training records, position profiles and experience profiles are complete and up-to-date. Ensures timeliness and accuracy of timesheets and expense reports.
- Supports allocation activities per the local resourcing process. Supports activities of project leads/functional leads to optimize the operational running of projects. Raises appropriately any issues which may impact project deliverables.
- Delivers training on Working Practice Documents (WPDs) and Standard Operating Procedures (SOPs), local requirements and any other subjects that impact on clinical operations. Identifies training gaps and ensures that training requirements are met. May contribute to development of training programs, where appropriate.
- Assures adherence to good ethical and regulatory standards.
- Alerts management to quality issues, request QA audits as appropriate, and facilitate client and internal quality assurance audits as required.
- Handles and reviews systems (e.g. Activate, CTMS, Preclarus, Clarity) to evaluate employee and project metrics, KPIs and general project status.
- Evaluates work of staff, including conducting PAVs (either remote or on-site) to thoroughly evaluate the employee monitoring skills and project conduction when applicable.
- Participates in process improvement/development initiatives.
- Ensures understanding and facilitation of the risk-based monitoring approach.
- May provide input into bids and contribute to the procurement of new business where required.
- Collaborates with clinical operations senior management and executive staff on strategic planning and business development as required.
- May lead or contribute to initiatives that enhance the department's performance or lead to process improvement across the company.
Education and Experience Requirements:
- Bachelor's degree or equivalent and relevant formal academic / vocational qualifications
- Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 0 to 5 years).
- 1+ year of leadership responsibility
- In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
Knowledge, Skills and Abilities:
- Advanced mentoring/leadership/supervisory skills
- Excellent clinical trials monitoring skills; Remote and on-site
- Demonstrated understanding of or ability to learn the company’s SOPs, WPDs, and relevant regulations (e.g. ICH/GCP, FDA guidelines)
- Demonstrated ability to evaluate medical research data
- Strong organizational and negotiation skills
- Strong attention to detail
- Advanced written and oral communication skills
- Good knowledge of English language and grammar
- Demonstrated use of computer to include data entry, archival and retrieval
- Ability to travel as needed
- Excellent teammate with team building skills
- Excellent interpersonal and conflict resolution skills
- Advanced ability to utilize problem-solving techniques applicable to constantly changing environment
- Solid knowledge of medical/therapeutic areas and medical terminology
Why Join Us?
When you join Thermo Fisher Scientific, you become part of a global team that values passion, innovation, and a commitment to scientific excellence. You’ll work in an environment where collaboration and development are part of the everyday experience—and where your contributions truly make a difference.
Apply today to help us deliver tomorrow’s breakthroughs.
Compensation and Benefits
The salary range estimated for this position based in California is $115,000.00–$180,000.00.This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
See All 373+ Clinical Manager Jobs in California
Find roles in California that match your experience and apply in just a few clicks.
Find Clinical Manager JobsClinical Manager Jobs by City in California
Where California roles are concentrated, by current openings.
Clinical Manager Job Market in California
A snapshot from current California openings, updated as new roles post.
Who's Hiring
- Independent Living Systems22
- Revolution Medicines12
- Kaiser Permanente8
- Katalyst Healthcares & Life Sciences8
- Catalight6
Top Industries Hiring
- Biotechnology & Pharmaceuticals17
- Insurance16
- Healthcare & Medical Services10
- Education3
- Non-Profit & Social Services3
What California Employers Look For
The qualifications that appear most often in clinical manager jobs across California.
- Active California RN license or other California-recognized clinical credential required
- Bachelor's degree in nursing, healthcare administration, or a related clinical field
- Minimum three to five years of direct clinical experience in a relevant care setting
- Prior supervisory or team leadership experience in a clinical or patient care environment
- Proficiency with electronic health record systems such as Epic or Cerner
- Knowledge of California Title 22 regulations and Joint Commission accreditation standards
Clinical Manager Jobs in California: Frequently Asked Questions
How do you become a clinical manager in California?
Most clinical manager roles in California require an active California RN license issued by the California Board of Registered Nursing, combined with a bachelor's degree in nursing or healthcare administration and several years of bedside or clinical experience. Many employers also prefer or require a Master of Science in Nursing or an MHA. Candidates with leadership experience in California's regulated acute care or behavioral health settings are consistently prioritized.
Which companies hire clinical managers in California?
Employers hiring clinical managers in California right now include Independent Living Systems, Revolution Medicines, and Kaiser Permanente, based on current listings on Migrate Mate as of October 2026. California's large integrated health systems, regional medical centers, and county public health departments are among the most consistent sources of clinical management openings in the state.
Which California cities have the most clinical manager jobs?
San Diego, San Francisco, and Los Angeles have the most clinical manager openings in California. Los Angeles and San Francisco lead because of their dense concentration of academic medical centers, large integrated health systems, and county health departments, while San Diego's mix of military health, biotech-affiliated clinics, and established hospital groups drives consistent demand in that market as well.
Are there remote clinical manager jobs in California?
Yes, but they're rare. Clinical manager roles are largely site-based because they involve direct oversight of staff, patient care operations, and regulatory compliance in physical care settings. About 49% of clinical manager openings tied to California are remote or hybrid as of October 2026, and those positions tend to be in utilization management, case management oversight, or telehealth program coordination rather than traditional unit or department management.
How can I get hired as a clinical manager in California with little or no experience?
The most realistic entry path is moving from a senior clinical role into a charge nurse or assistant manager position within a California hospital or outpatient network. Large California employers like Kaiser Permanente and Sutter Health run internal leadership development programs that prepare high-performing clinicians for management roles without requiring prior management titles. Earning a California RN license, pursuing a BSN if you hold an ADN, and volunteering for committee or quality improvement work strengthens a candidate's profile considerably.
Where can I find and apply to clinical manager jobs in California?
You can find and apply to clinical manager jobs in California on Migrate Mate, which lists current California openings across hospital systems, outpatient networks, and behavioral health organizations. Find roles that fit your experience and specialty and apply directly through each listing.
See All 373+ Clinical Manager Jobs in California
Find roles in California that match your experience and apply in just a few clicks.
Find Clinical Manager Jobs