COO Jobs in Colorado
COO jobs in Colorado are concentrated in Denver, Boulder, and Colorado Springs, where technology companies, aerospace firms, and healthcare systems drive consistent demand for senior operational leadership. Employers like Lockheed Martin, DaVita, and Centura Health maintain deep roots here and regularly seek coos with expertise in operational scaling, healthcare administration, or defense and aerospace operations. Colorado's growing startup ecosystem also creates openings for coos skilled in early-stage company building and venture-backed growth. See the openings below and apply to the ones that match your experience.
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Bring more to life.
Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology?
At Integrated DNA Technologies (IDT), one of Danaher’s 15+ operating companies, our work saves lives—and we’re all united by a shared commitment to innovate for tangible impact.
You’ll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher’s system of continuous improvement, you help turn ideas into impact – innovating at the speed of life.
Our team at Integrated DNA Technologies (IDT), is united by a commitment to collaboration and scientific excellence, building on a strong foundation of innovation, expertise, and reliability. Guided by our vision to help researchers rapidly move from the lab to life-changing advances, we work closely with global partners to accelerate progress and genomics breakthroughs across fields like cancer, infectious disease, rare genetic disorders, and more. At IDT, you’ll be part of a culture rooted in continuous learning and improvement—where your growth fuels our mission to accelerate the pace of genomics and helps shape a healthier, brighter future for all.
Learn about the Danaher Business System which makes everything possible.
The Site Director, Operations role is responsible for the overall performance, safety, and compliance of the Boulder biotechnology manufacturing site, ensuring alignment with regulatory standards. This role drives operational excellence by leading cross-functional teams, optimizing production processes, and fostering a culture of continuous improvement, Danaher Business Systems (DBS), employee engagement, and quality-first execution.
This position reports to the VP, Operations and is part of the IDT NGS Solutions Business team located in Boulder, Colorado and will be an on-site role.
In this role, you will have the opportunity to:
- Recruit, develop, and retain top talent while fostering a positive and inclusive team culture.
- Set, implement, and appropriately cascade SMART performance objectives for respective value streams/product lines, provide regular feedback, and foster professional development.
- Lead the improvement and harmonization of manufacturing processes . Ensure business is conducted with high integrity and in conformity with company policies, promote open communication, and resolve conflicts promptly.
- Ensure the shipment goals, business goals, customer requirements and production plans are achieved and that manufacturing capacity meets the sales plans
- Steer plant on-time delivery (OTD) of over 95% Establish high customer service goals and provide timely feedback to staff.
- Reduce costs through enhanced labor productivity, manufacturing efficiency, cycle times, expense mitigation, and material efficiency.
- Maintain a safe and compliant work environment. Coordinate cross-functional activities to meet regulatory and compliance standards. Ensure adherence to environmental regulations
The essential requirements of the job include:
- Bachelor’s degree in a life science or engineering-related field with at least 3-7 years of operations management experience.
- 3+ years of experience performing production tasks within an operations or supply chain environment.
- 3+ Previous people leader experience.
- Demonstrated leadership in continuous improvement such as 5S, Kanban, and other lean principles
- Track record of using operational metrics, process analysis, and business case development to drive measurable improvements.
- Experience in Stakeholder Management
- Demonstrated ability to align diverse teams around large-scale operational improvements and business transformations.
Travel, Motor Vehicle Record & Physical/Environment Requirements: if applicable for role
- Ability to travel – 25%
It would be a plus if you also possess previous experience in:
- Leadership development and coaching
- Good Manufacturing Practices (GMP)
IDT, a Danaher operating company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it’s a health care program or paid time off, our programs contribute to life beyond the job. Check out our benefits at Danaher Benefits Info.
This job is also eligible for bonus/incentive pay.
The annual salary range for this role is $140,000-$180,000. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. This range may be modified in the future.
This job is also eligible for bonus/incentive pay.
We offer comprehensive package of benefits including paid time off, medical/dental/vision insurance and 401(k) to eligible employees.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company’s sole discretion, consistent with the law.
Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.
For more information, visit www.danaher.com.
Bring more to life.
Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology?
At Integrated DNA Technologies (IDT), one of Danaher’s 15+ operating companies, our work saves lives—and we’re all united by a shared commitment to innovate for tangible impact.
You’ll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher’s system of continuous improvement, you help turn ideas into impact – innovating at the speed of life.
Our team at Integrated DNA Technologies (IDT), is united by a commitment to collaboration and scientific excellence, building on a strong foundation of innovation, expertise, and reliability. Guided by our vision to help researchers rapidly move from the lab to life-changing advances, we work closely with global partners to accelerate progress and genomics breakthroughs across fields like cancer, infectious disease, rare genetic disorders, and more. At IDT, you’ll be part of a culture rooted in continuous learning and improvement—where your growth fuels our mission to accelerate the pace of genomics and helps shape a healthier, brighter future for all.
Learn about the Danaher Business System which makes everything possible.
The Site Director, Operations role is responsible for the overall performance, safety, and compliance of the Boulder biotechnology manufacturing site, ensuring alignment with regulatory standards. This role drives operational excellence by leading cross-functional teams, optimizing production processes, and fostering a culture of continuous improvement, Danaher Business Systems (DBS), employee engagement, and quality-first execution.
This position reports to the VP, Operations and is part of the IDT NGS Solutions Business team located in Boulder, Colorado and will be an on-site role.
In this role, you will have the opportunity to:
- Recruit, develop, and retain top talent while fostering a positive and inclusive team culture.
- Set, implement, and appropriately cascade SMART performance objectives for respective value streams/product lines, provide regular feedback, and foster professional development.
- Lead the improvement and harmonization of manufacturing processes . Ensure business is conducted with high integrity and in conformity with company policies, promote open communication, and resolve conflicts promptly.
- Ensure the shipment goals, business goals, customer requirements and production plans are achieved and that manufacturing capacity meets the sales plans
- Steer plant on-time delivery (OTD) of over 95% Establish high customer service goals and provide timely feedback to staff.
- Reduce costs through enhanced labor productivity, manufacturing efficiency, cycle times, expense mitigation, and material efficiency.
- Maintain a safe and compliant work environment. Coordinate cross-functional activities to meet regulatory and compliance standards. Ensure adherence to environmental regulations
The essential requirements of the job include:
- Bachelor’s degree in a life science or engineering-related field with at least 3-7 years of operations management experience.
- 3+ years of experience performing production tasks within an operations or supply chain environment.
- 3+ Previous people leader experience.
- Demonstrated leadership in continuous improvement such as 5S, Kanban, and other lean principles
- Track record of using operational metrics, process analysis, and business case development to drive measurable improvements.
- Experience in Stakeholder Management
- Demonstrated ability to align diverse teams around large-scale operational improvements and business transformations.
Travel, Motor Vehicle Record & Physical/Environment Requirements: if applicable for role
- Ability to travel – 25%
It would be a plus if you also possess previous experience in:
- Leadership development and coaching
- Good Manufacturing Practices (GMP)
IDT, a Danaher operating company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it’s a health care program or paid time off, our programs contribute to life beyond the job. Check out our benefits at Danaher Benefits Info.
This job is also eligible for bonus/incentive pay.
The annual salary range for this role is $140,000-$180,000. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. This range may be modified in the future.
This job is also eligible for bonus/incentive pay.
We offer comprehensive package of benefits including paid time off, medical/dental/vision insurance and 401(k) to eligible employees.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company’s sole discretion, consistent with the law.
Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.
For more information, visit www.danaher.com.
See All 67 COO Jobs in Colorado
Find roles in Colorado that match your experience and apply in just a few clicks.
Find COO JobsCOO Jobs by City in Colorado
Where Colorado roles are concentrated, by current openings.
COO Job Market in Colorado
A snapshot from current Colorado openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Technology & Software
- Healthcare & Medical Services
- Consulting & Professional Services
What Colorado Employers Look For
The qualifications that appear most often in COO jobs across Colorado.
- Bachelor's or master's degree in business administration, operations, or a related field
- Ten or more years of progressive leadership experience in operations or a related function
- Demonstrated experience managing cross-functional teams and large organizational budgets
- Proven ability to develop and execute operational strategy aligned with company growth goals
- Experience in Colorado's key industries such as technology, aerospace, healthcare, or energy
- Strong background in financial planning, performance metrics, and executive-level reporting
COO Jobs in Colorado: Frequently Asked Questions
How do you become a coo in Colorado?
Becoming a coo in Colorado typically follows a path of progressive operational leadership rather than a state-issued license or exam, since no Colorado-specific credential is required for the role. Most coos hold a bachelor's degree in business, engineering, or operations, with many advancing their credentials through an MBA. Colorado employers in healthcare, aerospace, and technology prioritize candidates who have led large teams, managed P&L responsibility, and delivered measurable operational improvements at the director or VP level.
Which companies hire coos in Colorado?
Colorado coo roles are posted by UCHealth, IQVIA, and Sage Hospitality and others right now, based on current listings on Migrate Mate as of August 2026. Colorado's mix of established corporations, defense contractors, and venture-backed technology companies means coo demand comes from a wide range of employer types and sizes.
Which Colorado cities have the most coo jobs?
Denver, Colorado Springs, and Golden lead Colorado in coo openings, reflecting the concentration of corporate headquarters, major healthcare systems, and technology employers that anchor each market. Denver drives the largest share given its role as the state's primary business hub, while Boulder's innovation economy and Colorado Springs' defense and aerospace sector pull their own consistent demand for senior operational leaders.
Are there remote coo jobs in Colorado?
Yes, but they're rare. About 48% of coo openings tied to Colorado are remote or hybrid as of August 2026, reflecting that most organizations expect their chief operating officer to be present for board meetings, site visits, and daily leadership. The portions of the role most commonly handled remotely include strategic planning, financial reporting, and stakeholder communications.
How can I get hired as a coo in Colorado with little or no experience?
The most realistic entry path is moving into a director of operations or VP of operations role first, then building toward the coo title as your scope expands. Large Colorado employers in healthcare such as Centura Health and UCHealth, and technology companies along the Denver-Boulder corridor, regularly hire operations managers and directors who grow into senior executive positions. Completing an MBA from a Colorado institution like the University of Denver Daniels College of Business or CU Boulder Leeds School of Business strengthens your candidacy and builds a local professional network that Colorado employers recognize.
Where can I find and apply to coo jobs in Colorado?
You can find and apply to coo jobs in Colorado on Migrate Mate, which lists current Colorado openings updated regularly. Search the listings to find roles that fit your background, industry, and location preferences, then apply directly to the ones that match your experience.
See All 67 COO Jobs in Colorado
Find roles in Colorado that match your experience and apply in just a few clicks.
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