COO Jobs in New York
COO jobs in New York are among the most active in the country, concentrated in finance, media, technology, healthcare, and real estate across one of the world's most competitive executive markets, with openings from deputy COO and VP of operations through divisional and company-wide chief operating officer. New York City, White Plains, and Buffalo are the largest hiring centers, and established organizations like JPMorgan Chase, NBCUniversal, and NewYork-Presbyterian Hospital maintain consistent demand for operations leadership. The most sought-after specialties are financial services operations, digital transformation leadership, and healthcare system management. Find a role that fits below and apply directly.
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The Director, Strategic Partnerships and Business Operations is responsible for overseeing and ensuring compliance across a large portfolio of global investment and data licensing collaborations involving genetic and associated health data. This leader will be responsible for tracking and monitoring the research, business and finance deliverables of each collaboration, maintaining compliance and reporting out to leadership on the status of the active portfolio. The Director will be responsible for overseeing data governance, collaboration finance, strategic vendor contracting and Confidential Disclosure Agreement (CDA) processing, working in collaboration with senior leaders in research program management, business, legal and finance. The Director will oversee several headcount, both directly and indirectly in the management of this portfolio.
When & where:
- Location: Tarrytown, NY or Cambridge, MA
- Work model/flexibility: 4 days onsite
Discover your role:
- Track and manage compliance across a portfolio of 155+ global data licensing collaborations involving genetic and associated health data, including ongoing monitoring, risk assessment, and remediation.
- Oversee the development and operationalization of RGC data governance policies, procedures, consent frameworks, data use agreements, specific to genetic and health data; collaborate with the Privacy Office on privacy impact assessments and other regulatory requirements
- Lead, mentor, and develop a team of data governance and compliance professionals; foster a culture of accountability, transparency, and continuous learning.
- Collaborate cross-functionally with Legal (including the Privacy Office), IT Security, Research, and Business Development to embed privacy-by-design into data collaboration workflows and new initiatives.
This role requires:
- Master's degree in Genetics, Business, Legal, Bioethics, Life Sciences, or a related field; OR relevant degree with experience in contract compliance and sponsored research.
- An equivalent combination of advanced education and 15+ years of directly relevant experience may be considered.
- Minimum 10 years of progressive experience in contracting, alliance/portfolio management or compliance, with at least 5 years focused on genetic or health data in a research, biopharmaceutical, or biotech setting.
- Strong knowledge of genomic data governance frameworks, international privacy laws, including the NIH Genomic Data Sharing Policy and GA4GH standards.
- Exceptional written and verbal communication skills, with the ability to translate complex regulatory requirements for scientific, and executive audiences.
- Proven leadership ability with experience building and managing high-performing compliance teams.
Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.
Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.
Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.
As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.
For jobs in Canada: this posting is for an existing position.
Salary Range (annually)
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Where New York roles are concentrated, by current openings.
COO Job Market in New York
A snapshot from current New York openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Banking & Financial Services
- Education
- Luxury Goods
- Chemicals & Materials
What New York Employers Look For
The qualifications that appear most often in COO jobs across New York.
- Bachelor's degree in business administration, operations management, or a related field required
- Ten or more years of senior operations or leadership experience within a relevant New York industry
- Demonstrated experience scaling teams and processes in a high-growth or complex organization
- Strong financial acumen including P&L ownership and budget management across large portfolios
- Proven ability to collaborate with a CEO and board to execute organizational strategy
- Experience leading cross-functional teams in finance, technology, healthcare, or media sectors
COO Jobs in New York: Frequently Asked Questions
How do you become a coo in New York?
Becoming a coo in New York typically starts with a bachelor's degree in business, finance, or operations, followed by an MBA or equivalent advanced degree, which is strongly preferred by major New York employers. There is no state-issued license required to work as a coo in New York. Most candidates build their path through progressive leadership roles in operations, finance, or a sector-specific function within New York's dominant industries before stepping into the top role.
Which companies hire coos in New York?
Employers hiring coos in New York right now include Metropolitan Transportation Authority, RBC, and JPMorganChase, based on current listings on Migrate Mate as of September 2026. New York's concentration of financial institutions, media companies, and major hospital systems means demand for operations executives remains steady across multiple sectors throughout the year.
Which New York cities have the most coo jobs?
New York, Brooklyn, and Rochester have the most coo openings in New York. New York City dominates because it is home to the headquarters of major financial, media, and technology firms that require full-time on-site operations leadership, while secondary markets like White Plains and Buffalo reflect the presence of regional healthcare systems, manufacturers, and financial services branches that also maintain dedicated COO roles.
Are there remote coo jobs in New York?
Yes, but they're rare. About 63% of coo openings tied to New York are remote or hybrid as of September 2026, reflecting that most chief operating officer roles require regular in-person presence to manage staff, facilities, and executive relationships. The portions of the role most amenable to remote work include strategic planning, financial reporting, and cross-functional project oversight.
How can I get hired as a coo in New York with little or no experience?
The most realistic entry path is moving into a director of operations or VP of operations role first, as New York employers rarely hire first-time coos without prior senior leadership experience in the same sector. Large New York institutions such as major hospital networks, financial services firms, and media companies recruit operations directors who can grow into the COO seat over time. Building P&L responsibility and cross-functional team leadership in adjacent roles like chief of staff or senior operations director gives candidates the clearest edge.
Where can I find and apply to coo jobs in New York?
You can find and apply to coo jobs in New York on Migrate Mate, which lists current openings across New York City, the Hudson Valley, and upstate markets. Find roles that fit your experience and apply directly to the employers posting them.
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