COO Jobs in Missouri

COO jobs in Missouri are concentrated in St. Louis, Kansas City, and Springfield, where major employers such as Centene Corporation, Cerner (now Oracle Health), and Bass Pro Shops maintain significant operations and regularly hire senior operational leadership. Demand is strongest in healthcare systems, financial services, and consumer goods, with growing activity in logistics and technology. Missouri's diverse economy supports coo openings at both private companies and large nonprofits, drawing candidates at the divisional VP level through enterprise-wide executive roles. See the openings below and apply to the ones that match your experience.

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Overview

Open roles69
Top employerVillage Caregiving
Top citySt. Louis, MO
Cities hiring25
Work type57% On-site
Top credentialMaster's degree in business administration

Showing 5 of 69+ COO jobs

Assistant Dean & Director of Admissions Operations (Hybrid) - Olin Business
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Assistant Dean & Director of Admissions Operations (Hybrid) - Olin Business
Washington University in St. Louis
St. Louis, Missouri
Administrative & Office Support
Project & Program Management
Project Management
$66k - $113k/yr
Hybrid
Master's degree
10,000+

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Plant Operations Director
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Plant Operations Director
Raintree Village
Lees Summit, Missouri
Business Strategy
Product Management
Project Management
$57k.8 - $79k.8/yr

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Director of Operations
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Director of Operations
Hitachi Energy
Jefferson City, Missouri
Business Strategy
Corporate Development & M&A
Executive Leadership & C-Suite
On-Site
Bachelor's degree in business administration
10,000+

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Chief Operating Officer
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Chief Operating Officer
Macon County Samaritan Hospital - Macon, MO
Macon, Missouri
Business Development
Growth Marketing
Marketing
On-Site
Master's degree in business administration
201-500

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Director, Field Operations
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Director, Field Operations
Spire Energy
Kansas City, Missouri
Account Management
Customer Success
Partnerships & Business Development
Bachelor's degree

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See All 69 COO Jobs in Missouri

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COO Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

Springfield
6 jobs
Columbia
4 jobs
Wentzville
3 jobs
Chesterfield
3 jobs
Hazelwood
2 jobs
Earth City
2 jobs
Warrensburg
2 jobs

COO Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

Village Caregiving2 open roles
Cornerstone Caregiving2 open roles
BAYADA Home Health Care2 open roles

What Missouri Employers Look For

The qualifications that appear most often in COO jobs across Missouri.

  • Proven executive leadership experience managing cross-functional teams at a Missouri-based organization
  • Bachelor's degree in business administration, operations management, or a related field required
  • Demonstrated ability to align operational strategy with organizational goals and board-level expectations
  • Strong financial acumen including budget oversight, P&L responsibility, and capital planning
  • MBA or advanced degree preferred by most Missouri healthcare, finance, and enterprise employers
  • Experience driving process improvement initiatives using methodologies such as Lean or Six Sigma

COO Jobs in Missouri: Frequently Asked Questions

How do you become a coo in Missouri?

Becoming a coo in Missouri follows a career progression path rather than a state licensing requirement, as there is no Missouri-specific license or registration for this executive role. Most Missouri employers expect candidates to hold at least a bachelor's degree in business, operations, or a related field, with an MBA strongly preferred for enterprise roles. The typical path runs through director and VP-level positions in operations, finance, or a core business function within Missouri industries such as healthcare, logistics, or financial services.

Which companies hire coos in Missouri?

Missouri coo roles are posted by Village Caregiving, Cornerstone Caregiving, and BAYADA Home Health Care and others right now, based on current listings on Migrate Mate as of November 2026. Missouri's mix of Fortune 500 headquarters, regional health systems, and established manufacturing companies creates a consistent pipeline of senior operational leadership openings throughout the state.

Which Missouri cities have the most coo jobs?

St. Louis, Kansas City, and Springfield account for the largest share of coo openings in Missouri. St. Louis and Kansas City dominate because they are home to major corporate headquarters and large regional health systems, while Springfield's concentration of retail, insurance, and distribution employers drives demand in southwest Missouri for operational executives who can manage complex, multi-site organizations.

Are there remote coo jobs in Missouri?

Yes, but they're rare. About 43% of coo openings tied to Missouri are remote or hybrid as of November 2026, reflecting the reality that most coo roles require regular in-person presence to lead teams, oversee facilities, and engage with boards or ownership groups. Strategy and reporting functions are the portions of the role most compatible with remote or hybrid flexibility.

How can I get hired as a coo in Missouri with little or no experience?

The most realistic entry point is moving into a director of operations or VP of operations role at a mid-size Missouri company, then building toward the coo title over time. Large health systems like BJC HealthCare and Mercy Health develop operational leaders through internal promotion pipelines, and Missouri's manufacturing and logistics sectors regularly advance plant managers or supply chain directors into broader executive roles. A strong MBA from a Missouri institution such as Washington University in St. Louis or the University of Missouri adds measurable credibility when competing for that first senior leadership seat.

Where can I find and apply to coo jobs in Missouri?

You can find and apply to coo jobs in Missouri on Migrate Mate, which lists current Missouri openings updated on an ongoing basis. Search the listings to find roles that match your experience level, industry background, and preferred location, then apply directly to the ones that fit.

See All 69 COO Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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