COO Jobs in Missouri

COO jobs in Missouri are concentrated in St. Louis, Kansas City, and Springfield, where major employers such as Centene Corporation, Cerner (now Oracle Health), and Bass Pro Shops maintain significant operations and regularly hire senior operational leadership. Demand is strongest in healthcare systems, financial services, and consumer goods, with growing activity in logistics and technology. Missouri's diverse economy supports coo openings at both private companies and large nonprofits, drawing candidates at the divisional VP level through enterprise-wide executive roles. See the openings below and apply to the ones that match your experience.

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Overview

Open roles47
Top employerWashington University in St. Louis
Top citySt. Louis, MO
Cities hiring15
Work type57% On-site
Top industryConsulting

Showing 5 of 47+ COO jobs

University Missouri St.Louis
Assistant Athletic Director for Facilities & Operations
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University Missouri St.Louis
Added 1d ago
Assistant Athletic Director for Facilities & Operations
University Missouri St.Louis
St. Louis, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
$58k - $620k/yr
Master's degree in business administration
201-500

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Discovery Senior Living
Regional Director of Operations (Senior Living - Extensive Travel)
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Discovery Senior Living
Added 1d ago
Regional Director of Operations (Senior Living - Extensive Travel)
Discovery Senior Living
Kansas City, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
Bachelor's degree
5,001-10,000

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Washington University in St. Louis
Senior Associate Director Of Gift Operations - University Advancement
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Washington University in St. Louis
Added 1d ago
Senior Associate Director Of Gift Operations - University Advancement
Washington University in St. Louis
St. Louis, Missouri
Administrative & Office Support
Business Analysis
Project Management
$66k - $113k/yr
Bachelor's degree
10,000+

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Associated Electric Cooperative Inc
Managing Director, Technology Operations
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Associated Electric Cooperative Inc
Added 5d ago
Managing Director, Technology Operations
Associated Electric Cooperative Inc
Springfield, Missouri
Customer Support
IT Support
Technical Program Management
Bachelor's degree in business
501-1,000

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Washington University in St. Louis
Director of Operations & Finance (Hybrid) - Office of Technology Managment
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Washington University in St. Louis
Added 5d ago
Director of Operations & Finance (Hybrid) - Office of Technology Managment
Washington University in St. Louis
St. Louis, Missouri
Business Development
Growth Marketing
Marketing
$96k - $169k/yr
Hybrid
Bachelor's degree
10,000+

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See All 47 COO Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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COO Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

Springfield
3 jobs
Chesterfield
3 jobs
Columbia
2 jobs
Rolla
1 job
Belton
1 job
Nevada
1 job
Pacific
1 job

COO Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

Washington University in St. Louis
Washington University in St. Louis3 open roles
CRB
CRB2 open roles
Key Rehabilitation
Key Rehabilitation2 open roles

Top Industries Hiring

  • Consulting & Professional Services
  • Education
  • Accounting & Auditing
  • Media & Entertainment
  • Technology & Software

What Missouri Employers Look For

The qualifications that appear most often in COO jobs across Missouri.

  • Proven executive leadership experience managing cross-functional teams at a Missouri-based organization
  • Bachelor's degree in business administration, operations management, or a related field required
  • Demonstrated ability to align operational strategy with organizational goals and board-level expectations
  • Strong financial acumen including budget oversight, P&L responsibility, and capital planning
  • MBA or advanced degree preferred by most Missouri healthcare, finance, and enterprise employers
  • Experience driving process improvement initiatives using methodologies such as Lean or Six Sigma

COO Jobs in Missouri: Frequently Asked Questions

How do you become a coo in Missouri?

Becoming a coo in Missouri follows a career progression path rather than a state licensing requirement, as there is no Missouri-specific license or registration for this executive role. Most Missouri employers expect candidates to hold at least a bachelor's degree in business, operations, or a related field, with an MBA strongly preferred for enterprise roles. The typical path runs through director and VP-level positions in operations, finance, or a core business function within Missouri industries such as healthcare, logistics, or financial services.

Which companies hire coos in Missouri?

Missouri coo roles are posted by Washington University in St. Louis, CRB, and Key Rehabilitation and others right now, based on current listings on Migrate Mate as of August 2026. Missouri's mix of Fortune 500 headquarters, regional health systems, and established manufacturing companies creates a consistent pipeline of senior operational leadership openings throughout the state.

Which Missouri cities have the most coo jobs?

St. Louis, Kansas City, and Springfield account for the largest share of coo openings in Missouri. St. Louis and Kansas City dominate because they are home to major corporate headquarters and large regional health systems, while Springfield's concentration of retail, insurance, and distribution employers drives demand in southwest Missouri for operational executives who can manage complex, multi-site organizations.

Are there remote coo jobs in Missouri?

Yes, but they're rare. About 43% of coo openings tied to Missouri are remote or hybrid as of August 2026, reflecting the reality that most coo roles require regular in-person presence to lead teams, oversee facilities, and engage with boards or ownership groups. Strategy and reporting functions are the portions of the role most compatible with remote or hybrid flexibility.

How can I get hired as a coo in Missouri with little or no experience?

The most realistic entry point is moving into a director of operations or VP of operations role at a mid-size Missouri company, then building toward the coo title over time. Large health systems like BJC HealthCare and Mercy Health develop operational leaders through internal promotion pipelines, and Missouri's manufacturing and logistics sectors regularly advance plant managers or supply chain directors into broader executive roles. A strong MBA from a Missouri institution such as Washington University in St. Louis or the University of Missouri adds measurable credibility when competing for that first senior leadership seat.

Where can I find and apply to coo jobs in Missouri?

You can find and apply to coo jobs in Missouri on Migrate Mate, which lists current Missouri openings updated on an ongoing basis. Search the listings to find roles that match your experience level, industry background, and preferred location, then apply directly to the ones that fit.

See All 47 COO Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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