RN Staff Nurse Jobs in Minnesota

RN Staff Nurse jobs in Minnesota are concentrated in hospital systems, long-term care facilities, and specialty outpatient clinics, with demand strong at every level from new-grad to experienced charge-level staff. The busiest hiring markets are the Twin Cities metro, Rochester, and Duluth, where employers like Mayo Clinic, M Health Fairview, and Allina Health maintain large and ongoing nursing workforces. Critical care, medical-surgical, and behavioral health are among the most consistently open specialties across the state. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles10
Top employerHennepin Healthcare
Top cityMinneapolis, MN
Cities hiring3
Work type100% On-site
Top industryHealthcare

Showing 4 of 10+ RN Staff Nurse jobs

Staff Nurse (RN) - OB Inpatient
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Added 3d ago
Staff Nurse (RN) - OB Inpatient
Hennepin Healthcare
Minneapolis, Minnesota
Healthcare Administration
Patient Services & Wellbeing
Public Health
$36 - $69/hr
Bachelor of Science in Nursing
5,001-10,000

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Staff Nurse (RN) - OB Resource Pool
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Added 3d ago
Staff Nurse (RN) - OB Resource Pool
Hennepin Healthcare
Minneapolis, Minnesota
Healthcare Administration
Nursing
Patient Services & Wellbeing
$36.7 - $69.38/hr
Bachelor of Science in Nursing
5,001-10,000

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Staff Nurse- MA, LPN, RN
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Added 1w ago
Staff Nurse- MA, LPN, RN
Dermatology Professionals
Baxter, Minnesota
Healthcare Administration
Nursing
Patient Services & Wellbeing
$22 - $30/hr

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Staff Nurse (RN) - SICU
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Added 1mo ago
Staff Nurse (RN) - SICU
Hennepin Healthcare
Minneapolis, Minnesota
Clinical Trials
Healthcare Administration
Nursing
Patient Services & Wellbeing
$36.7 - $69.38/hr
Bachelor of Science in Nursing
5,001-10,000

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RN Staff Nurse Jobs by City in Minnesota

Where Minnesota roles are concentrated, by current openings.

Minneapolis
8 jobs
Baxter
1 job
Albert Lea
1 job

RN Staff Nurse Job Market in Minnesota

A snapshot from current Minnesota openings, updated as new roles post.

Who's Hiring

Hennepin Healthcare7 open roles
Dermatology Professionals1 open role
St John's Lutheran Community1 open role

Top Industries Hiring

  • Healthcare & Medical Services

What Minnesota Employers Look For

The qualifications that appear most often in RN staff nurse jobs across Minnesota.

  • Active Minnesota RN license or a Nurse Licensure Compact license recognized in Minnesota
  • Associate or bachelor's degree in nursing from an accredited program
  • Current BLS certification required before the first day of clinical work
  • Minimum one year of acute care or specialty unit experience for most staff nurse roles
  • Strong familiarity with electronic health record systems such as Epic or Cerner
  • Ability to work rotating shifts including nights, weekends, and holidays as scheduled

RN Staff Nurse Jobs in Minnesota: Frequently Asked Questions

How do you become a rn staff nurse in Minnesota?

You must hold an active registered nurse license issued by the Minnesota Board of Nursing, which requires completing an accredited associate or bachelor's degree nursing program and passing the NCLEX-RN exam. Minnesota participates in the Nurse Licensure Compact, so nurses already licensed in another compact state can work in Minnesota without obtaining a separate state license. New graduates typically apply directly to hospital-based residency programs or entry-level staff nurse openings listed by major health systems in the state.

How much do RN staff nurses make in Minnesota?

RN staff nurses in Minnesota earn a median of about $101,510 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $79,960 for the lowest 10% to over $132,430 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire rn staff nurses in Minnesota?

Companies currently hiring rn staff nurses in Minnesota include Hennepin Healthcare, Dermatology Professionals, and St John's Lutheran Community, per current listings on Migrate Mate as of October 2026. Minnesota's large integrated health systems and regional medical centers account for the majority of open staff nurse positions across the state.

Which Minnesota cities have the most rn staff nurse jobs?

Minneapolis, Baxter, and Albert Lea lead Minnesota in rn staff nurse openings. The Twin Cities metro drives the largest share of listings given the concentration of major health system headquarters and academic medical centers there, while Rochester's volume reflects the scale of Mayo Clinic's operations, and Duluth serves as the primary hub for northeastern Minnesota's hospital and long-term care networks.

Are there remote rn staff nurse jobs in Minnesota?

Yes, but they're rare. Hands-on patient care requires in-person presence, so the overwhelming majority of rn staff nurse roles are facility-based. About 0% of rn staff nurse openings tied to Minnesota are remote or hybrid as of October 2026, and those positions tend to be in care coordination, telephonic triage, or utilization review rather than direct bedside nursing.

How can I get hired as a rn staff nurse in Minnesota with little or no experience?

The most realistic entry path is a nurse residency or new-graduate program, which large Minnesota employers such as Mayo Clinic, Allina Health, and M Health Fairview run specifically for nurses who lack professional experience after licensure. These structured programs pair new nurses with mentors on specific units and are designed to bridge the gap between clinical training and independent practice. Candidates strengthen their position by completing their NCLEX-RN promptly after graduation, targeting med-surg or general acute care units as first placements, and highlighting clinical rotations completed at Minnesota facilities.

Where can I find and apply to rn staff nurse jobs in Minnesota?

You can find and apply to rn staff nurse jobs in Minnesota on Migrate Mate, which lists current openings across the state. Search the available roles, identify the ones that match your experience and preferred location, and apply directly to each position that fits.

See All 10 RN Staff Nurse Jobs in Minnesota

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