Business Operations Manager Jobs in Missouri
Business Operations Manager jobs in Missouri are consistently in demand, with strong hiring concentrated in healthcare administration, financial services, logistics, and manufacturing across the state. Kansas City and St. Louis anchor the market, with Springfield contributing a steady share of mid-market openings, and established employers such as Cerner (now Oracle Health), Edward Jones, and Emerson Electric regularly seek business operations managers at both mid-level and senior levels. Process improvement, vendor management, and cross-functional program coordination are the specialties most consistently requested in Missouri listings. Scan the live roles below and apply to whichever ones fit.
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Our Purpose
Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential.
Title and Summary
Vice President, Business Operations
Vice President, Business Operations – File Transfer
Overview:
File Transfer Business Operations team is looking for a Vice President (VP) to lead a team of Site Reliability Engineers (SREs) and application operations support staff. The Vice President is responsible for the strategy and execution of the teams, managing day to day platform availability, Tier 2 & 3 production support, CI/CD pipelines, customer support and integrations, platform automation, monitoring/alerting, system resiliency and scalability, and ITSM maturity. The ideal candidate is a problem solver with a strong background in operations, application and infrastructure technologies, and design patterns who is curious to figure out how something works and how it can be improved through automation, AI-enabled tooling, improving availability, reducing manual toil, and continually refining our processes to be more efficient.
The Vice President will lead global teams that span support for a number of products and services within File Transfer. These products are used by both internal and external customers.
Business Operations is leading the DevOps and AI-enabled operations transformation at Mastercard through our tooling and by being an advocate for change & standards throughout the development, quality, release, and product organizations. We need team members who are curious and with an appetite for change and pushing the boundaries of what can be done with automation and agentic tooling. Experience in working across development, operations, and product teams to prioritize needs and to build relationships is a must.
Responsibilities
- Hire, manage, and coach Site Reliability Engineers to deliver World Class Support for internally and externally used products
- Engage in and improve the whole lifecycle of services—from inception and design, through deployment, operations, and refinement
- Drive the automation agenda for the team — identifying high-toil, repetitive operational work and championing automation and AI-enabled tooling to eliminate it
- Support and help operate the data and AI/ML platforms that underpin internal reporting, decisioning, and back-office functions, ensuring the same reliability and operational rigor applied to traditional application platforms
- Analyze ITSM activities of the platform and provide feedback loop to development teams on operational gaps or resiliency concerns
- Support services before they go live through activities such as system design consulting, capacity planning and launch reviews
- Maintain services once they are live by measuring and monitoring availability, latency and overall system health
- Scale systems sustainably through mechanisms like automation and AI-assisted operations, and evolve systems by pushing for changes that improve reliability and velocity
- Support the application CI/CD pipeline for promoting software into higher environments through validation and operational gating, and lead Mastercard in DevOps automation and best practices
- Practice sustainable incident response and blameless postmortems
- Take a holistic approach to problem solving, by connecting the dots during a production event thru the various technology stack that makes up the platform, to optimize mean time to recover. Constantly improve processes — including through automation and AI-assisted diagnostics — to ensure full root cause analysis is occurring
- Work with a global team spread across tech hubs in multiple geographies and time zones
- Share knowledge and mentor others, including building the team's fluency in automation and AI-enabled operational tooling
Qualifications
- BS degree in Computer Science or related technical field involving coding (e.g., physics or mathematics), or equivalent practical experience
- Experience with databases (SQL and NoSQL), algorithms, data structures, scripting, pipeline management, and software design
- Knowledge of Java applications and middleware
- Experience supporting or operating data platforms and/or AI/ML systems (e.g., data pipelines, model serving, observability for AI-driven services) strongly preferred
- Demonstrated track record of driving automation to reduce manual toil and improve operational efficiency at scale
- Familiarity with applying AI-enabled tooling to operations — such as intelligent alerting, automated triage, or agentic remediation — is a plus
- Systematic problem-solving approach, coupled with strong communication skills and a sense of ownership and drive
- Strong written and verbal communication skills to interact with our regional teams, customers and executive management
- We support many different stakeholders. Experience in dealing with difficult situations and making decisions with a sense of urgency is needed
- Interest in designing, analyzing and troubleshooting large-scale distributed systems
- We need team members with an appetite for change and pushing the boundaries of the way things have been done, particularly through automation and AI. Experience in working across development, operations, and product teams to prioritize needs and to build relationships is a must
- Experience managing 3rd parties via SOWs
- Creating, tracking, and measuring people and service providers against metrics to measure performance & results
Mastercard is a merit-based, inclusive, equal opportunity employer that considers applicants without regard to gender, gender identity, sexual orientation, race, ethnicity, disabled or veteran status, or any other characteristic protected by law. We hire the most qualified candidate for the role. In the US or Canada, if you require accommodations or assistance to complete the online application process or during the recruitment process, please contact reasonable_accommodation@mastercard.com and identify the type of accommodation or assistance you are requesting. Do not include any medical or health information in this email. The Reasonable Accommodations team will respond to your email promptly.
Corporate Security Responsibility
All activities involving access to Mastercard assets, information, and networks comes with an inherent risk to the organization and, therefore, it is expected that every person working for, or on behalf of, Mastercard is responsible for information security and must:
- Abide by Mastercard’s security policies and practices;
- Ensure the confidentiality and integrity of the information being accessed;
- Report any suspected information security violation or breach, and
- Complete all periodic mandatory security trainings in accordance with Mastercard’s guidelines.
In line with Mastercard’s total compensation philosophy and assuming that the job will be performed in the US, the successful candidate will be offered a competitive base salary and may be eligible for an annual bonus or commissions depending on the role. The base salary offered may vary depending on multiple factors, including but not limited to location, job-related knowledge, skills, and experience. Mastercard benefits for full time (and certain part time) employees generally include: insurance (including medical, prescription drug, dental, vision, disability, life insurance); flexible spending account and health savings account; paid leaves (including 16 weeks of new parent leave and up to 20 days of bereavement leave); 80 hours of Paid Sick and Safe Time, 25 days of vacation time and 5 personal days, pro-rated based on date of hire; 10 annual paid U.S. observed holidays; 401k with a best-in-class company match; deferred compensation for eligible roles; fitness reimbursement or on-site fitness facilities; eligibility for tuition reimbursement; and many more. Mastercard benefits for interns generally include: 56 hours of Paid Sick and Safe Time; jury duty leave; and on-site fitness facilities in some locations.
THIS POSTING RELECTS ONE OR MORE CURRENT VACANCIES ON OUR TEAM, AND MASTERCARD INTENDS TO FILL THIS POSITION BY 02/03/2027. If the fill date has passed, Mastercard intends to fill this position as soon as possible.
Pay Ranges
O'Fallon, Missouri: $200,000 - $330,000 USD
See All 26 Business Operations Manager Jobs in Missouri
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Where Missouri roles are concentrated, by current openings.
Business Operations Manager Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring



What Missouri Employers Look For
The qualifications that appear most often in business operations manager jobs across Missouri.
- Bachelor's degree in business administration, operations management, or a related field
- Three or more years of experience in operations, project management, or business analysis
- Demonstrated experience managing budgets, forecasts, or resource planning across departments
- Proficiency with ERP systems, CRM platforms, or business intelligence tools such as Salesforce or SAP
- Strong cross-functional communication skills to coordinate between teams and senior leadership
- PMP certification or Lean Six Sigma credential preferred by many Missouri employers
Business Operations Manager Jobs in Missouri: Frequently Asked Questions
How do you become a business operations manager in Missouri?
There is no state-issued license required to work as a business operations manager in Missouri. Most employers look for a bachelor's degree in business administration, management, or a related discipline, combined with progressive experience in operations or project coordination. Earning a Project Management Professional certification or a Lean Six Sigma credential strengthens your application considerably, as Missouri employers in healthcare, logistics, and financial services regularly list these credentials as preferred qualifications.
How much do business operations managers make in Missouri?
Business operations managers in Missouri earn a median of about $79,300 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $42,460 for the lowest 10% to over $188,820 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire business operations managers in Missouri?
Companies currently hiring business operations managers in Missouri include Washington University in St. Louis, CarMax, and QinetiQ, per current listings on Migrate Mate as of November 2026. Missouri's mix of large corporate headquarters, regional healthcare systems, and logistics operators means openings appear across a wide range of industries and company sizes.
Which Missouri cities have the most business operations manager jobs?
St. Louis, Kansas City, and Columbia account for the highest concentration of business operations manager openings in Missouri. Kansas City drives volume through its financial services, healthcare, and logistics sectors, St. Louis benefits from a dense cluster of corporate headquarters and large regional employers, and Springfield's growing healthcare and retail distribution base sustains a consistent share of mid-level openings.
Are there remote business operations manager jobs in Missouri?
Yes, and more than most fields, because business operations management centers on coordination, analysis, and communication work that translates well to distributed teams. About 60% of business operations manager openings tied to Missouri are remote or hybrid as of November 2026, reflecting how broadly companies have adopted flexible arrangements for this role. Functions such as vendor management, reporting, and process documentation are most commonly performed remotely.
How can I get hired as a business operations manager in Missouri with little or no experience?
The most realistic entry path is moving into the role from an adjacent position such as operations coordinator, business analyst, or project administrator. Large Missouri employers in healthcare and financial services, including regional hospital systems and insurance carriers based in Kansas City and St. Louis, routinely post associate operations roles designed for candidates with limited direct experience. Building proficiency in ERP or project management software and completing a Lean Six Sigma White or Yellow Belt course gives candidates a measurable edge when applying to these entry-level tracks.
Where can I find and apply to business operations manager jobs in Missouri?
You can find and apply to business operations manager jobs in Missouri on Migrate Mate, which lists current Missouri openings updated in real time. Search the listings, find the roles that fit your background and preferred location, and apply directly to the ones that match. No account is required to view or apply to the positions listed.
See All 26 Business Operations Manager Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
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