Clinical Research Nurse Jobs in Minnesota
Clinical Research Nurse jobs in Minnesota concentrate in academic medical centers, large integrated health systems, and pharmaceutical and medical device companies, reflecting the state's dense life sciences corridor. Most hiring activity is in Minneapolis, Rochester, and Saint Paul, where employers such as Mayo Clinic, M Health Fairview, and Allina Health maintain sustained clinical trial programs. Oncology, cardiology, and neurology trials draw the steadiest demand, with openings at every experience level from entry-level coordinators to senior principal investigators. Scan the live roles below and apply to whichever ones fit.
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Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact.
A Day in the Life
This position will be a full-time S&SS CRS position supporting the CAS Site Management Team.In this exciting role as a Clinical Research Specialist, you will have primary focus responsibility in preparing sites for data collection, relationship building with research coordinators, regulatory report writing, and data cleaning. The CRS works under the direction of a Clinical Study Manager and assists with numerous tasks associated with the execution of a clinical trial.
The Study & Scientific Solutions (S&SS) is a function within Medtronic Core Clinical Solutions (MC2). S&SS is an internal service provider to all of Medtronic and assigns resources to assist Business Units execute on clinical trials and scientific projects when they have an increase in workload.
At Medtronic, we bring bold ideas forward with speed and decisiveness to put patients first in everything we do. This position is remote to enhance our competitive edge and expand our cross-functional collaboration efforts. This role will require 10% of travel to enhance collaboration and ensure successful completion of projects.
Responsibilities may include the following and other duties may be assigned.
Oversees, designs, plans and develops clinical evaluation research studies.
Prepares and authors protocols and patient record forms.
Conducts registered and non-registered clinical studies of products that have been determined to satisfy a medical need and/or offer a commercial potential.
Oversees and interpret results of clinical investigations in preparation for new drug device or consumer application.
Oversees and resolves operational aspects of clinical trials in conjunction with project teams and in accordance with standard operating procedures (SOP), good clinical practice (GCP) and specific country regulations, and may prepare clinical trial budgets.
May be responsible for clinical supply operations, site and vendor selection.
People working within region/country may also have the responsibilities that include:
Represents Medtronic from a clinical research respective within the country / region and also collects feedback from local customers and authorities.
Builds and maintains optimal relationships and effective collaborations with various internal and external parties.
Drives local evidence dissemination & awareness.
Minimum Requirements:
Bachelor's degree plus 2+ years of clinical site management experience
Nice to Have:
Bachelor's degree in degree in engineering, life sciences, or related medical/scientific field
Previous Medtronic experience
Clinical experience
Site Management experience (site or sponsor)
Knowledge of/experience with CTMS/EDC/TMF
Experience with Good Clinical Practice (GCP)
For Baccalaureate degrees earned outside of the United States, a degree that satisfies the requirements of 8 C.F.R. § 214.2(h)(4)(iii)(A) is required.
Physical Job Requirements
The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position.
The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role.
U.S. Work Authorization & Sponsorship
At Medtronic, we are committed to fostering an environment where employees can thrive and make a meaningful impact. In alignment with our enterprise-wide workforce planning approach, U.S. work authorization sponsorship (H-1B, TN, J, etc.) is offered exclusively for Principal-level roles and above, where specialized expertise aligns with long-term business needs. Roles below the Principal level require candidates to possess unrestricted U.S. work authorization at the time of hire and for the duration of employment.
Recruitment Fraud Alert
We are aware of phishing scams targeting job seekers. Please keep the following in mind:
Apply only through official Medtronic channels. All legitimate Medtronic recruiting communications come from approved Medtronic platforms and official @medtronic.com email addresses.
Medtronic will never ask for payment or sensitive personal information (such as bank account or Social Security details) during early stages of the hiring process. Any such requests are not legitimate.
If you receive a suspicious message claiming to be from Medtronic, do not respond, click links, or open attachments.
If you have any questions, concerns regarding the authenticity of a communication alleged to have been made by or on behalf of Medtronic, please contact us immediately at AskHR@medtronic.com .
Benefits & Compensation
Medtronic offers a competitive Salary and flexible Benefits Package
A commitment to our employees lives at the core of our values. We recognize their contributions. They share in the success they help to create. We offer a wide range of benefits, resources, and competitive compensation plans designed to support you at every career and life stage.
This position is eligible for a short-term incentive called the Medtronic Incentive Plan (MIP). The base salary range is applicable across the United States, excluding Puerto Rico and specific locations in California. The offered rate complies with federal and local regulations and may vary based on factors such as experience, certification/education, market conditions, and location. Compensation and benefits information pertains solely to candidates hired within the United States (local market compensation and benefits will apply for others).
The following benefits and additional compensation are available to those regular employees who work 20+ hours per week: Health, Dental and vision insurance , Health Savings Account , Healthcare Flexible Spending Account , Life insurance, Long-term disability leave , Dependent daycare spending account , Tuition assistance/reimbursement , and Simple Steps (global well-being program).
The following benefits and additional compensation are available to all regular employees: Incentive plans, 401(k) plan plus employer contribution and match , Short-term disability , Paid time off , Paid holidays , Employee Stock Purchase Plan , Employee Assistance Program , Non-qualified Retirement Plan Supplement (subject to IRS earning minimums) , and Capital Accumulation Plan (available to Vice Presidents and above, or subject to IRS earning minimums).
Regular employees are those who are not temporary, such as interns. Temporary employees are eligible for paid sick time, as required under applicable state law, and the Employee Stock Purchase Plan. Please note some of the above benefits may not apply to workers in Puerto Rico.
Further details are available at the link below:
Medtronic benefits and compensation plans
It is the policy of Medtronic to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, Medtronic will provide reasonable accommodations for qualified individuals with disabilities.
If you are applying to perform work for Medtronic, Inc. (“Medtronic”) in any position which will involve performing at least two (2) hours of work on average each week within the unincorporated areas of Los Angeles County, you can find here a list of all material job duties of the specific job position which Medtronic reasonably believes that criminal history may have a direct, adverse and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. Medtronic will consider for employment qualified job applicants with arrest or conviction records in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
See All 30 Clinical Research Nurse Jobs in Minnesota
Find roles in Minnesota that match your experience and apply in just a few clicks.
Find Clinical Research Nurse JobsClinical Research Nurse Jobs by City in Minnesota
Where Minnesota roles are concentrated, by current openings.
Clinical Research Nurse Job Market in Minnesota
A snapshot from current Minnesota openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Education
- Medical Devices
- Distribution & Wholesale
What Minnesota Employers Look For
The qualifications that appear most often in clinical research nurse jobs across Minnesota.
- Active registered nurse license issued or recognized by the Minnesota Board of Nursing
- Bachelor of Science in Nursing or higher from an accredited program
- One or more years of clinical nursing experience in a hospital or research setting
- Certification as a Clinical Research Professional through ACRP or SOCRA preferred
- Demonstrated knowledge of Good Clinical Practice guidelines and ICH standards
- Experience with electronic data capture systems such as REDCap or Medidata
Clinical Research Nurse Jobs in Minnesota: Frequently Asked Questions
How do you become a clinical research nurse in Minnesota?
You must first hold an active registered nurse license issued by the Minnesota Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN. From there, most Minnesota employers expect at least some bedside experience before moving into a research role. Earning a Clinical Research Professional credential through ACRP or SOCRA strengthens your application, and many candidates gain an edge by starting as a clinical research coordinator at a major academic or health system site.
Which companies hire clinical research nurses in Minnesota?
Minnesota clinical research nurse roles are posted by University of Minnesota, Mayo Clinic, and Medtronic and others right now, based on current listings on Migrate Mate as of August 2026. Minnesota's deep network of academic medical centers, integrated health systems, and medical device companies means sustained hiring across a range of therapeutic areas and trial phases.
Which Minnesota cities have the most clinical research nurse jobs?
Minneapolis, Rochester, and Minnesota have the most clinical research nurse openings in Minnesota. Minneapolis anchors the market as home to large health systems and a growing biotech cluster, while Rochester draws consistent volume from Mayo Clinic's extensive clinical trials enterprise, and smaller suburban and secondary markets benefit from satellite campuses and community research sites operated by those same major employers.
Are there remote clinical research nurse jobs in Minnesota?
Yes, but they're rare. About 53% of clinical research nurse openings tied to Minnesota are remote or hybrid as of August 2026, reflecting the hands-on patient contact most trial roles require. The portions of the work most suited to remote arrangements include protocol review, regulatory documentation, data query resolution, and sponsor communication, rather than visit coordination or patient assessment.
How can I get hired as a clinical research nurse in Minnesota with little or no experience?
The most realistic entry path is applying for a clinical research coordinator or research assistant role at an academic medical center while you still hold an active Minnesota RN license. Mayo Clinic, M Health Fairview, and Allina Health each run structured research onboarding programs that accept candidates with limited trial experience. Moving laterally from a med-surg, oncology, or infusion unit gives you patient-interaction and documentation skills that research teams value, and completing a Good Clinical Practice training course before you apply gives your application a concrete edge.
Where can I find and apply to clinical research nurse jobs in Minnesota?
You can find and apply to clinical research nurse jobs in Minnesota on Migrate Mate, which lists current Minnesota openings across health systems, academic medical centers, and life sciences companies. Search the available roles, find the ones that match your experience and specialty area, and apply directly to the ones that fit.
See All 30 Clinical Research Nurse Jobs in Minnesota
Find roles in Minnesota that match your experience and apply in just a few clicks.
Find Clinical Research Nurse Jobs