Clinical Research Nurse Jobs in Minnesota
Clinical Research Nurse jobs in Minnesota are open across Minneapolis and Rochester and other Minnesota metros, with employers like Allina Health, University of Minnesota, and Mayo Clinic hiring at every experience level. Find a role that fits below and apply directly.
Find Clinical Research Nurse JobsOverview
Showing 5 of 6+ Clinical Research Nurse jobs
Where Purpose Meets Progress
At the Minneapolis Heart Institute Foundation (MHIF), your dedication fuels innovation, transforms patient care, and helps shape the future of cardiovascular medicine. As a Research Nurse, your role goes beyond the bedside—you become a vital connection between patients and research that leads to life-saving discoveries.
Job Summary
In support of the Minneapolis Heart Institute Foundation (MHIF) mission, Clinical Research Coordinators (CRC) provide support, coordination and leadership for research studies that may involve industry sponsored Phase I, II, III, and IV clinical trials, drug, biologic, device, government-funded clinical research and investigator-initiated clinical research. They ensure smooth, accurate progress of clinical studies in accordance with all legal and regulatory standards from the planning and approval stages through study completion and post-study closure. CRC’s assist with documentation for Institutional Review Board (IRB) submissions, recruit and screen study participants and help facilitate their continued participation; abstract data from electronic medical records (EMR) and other sources; collect, submit and maintain study data and regulatory documents; ensure compliance with study protocols and participate in initial budget discussion for clinical trials.
Primary Responsibilities
Ensures Human Subject Protection
- Determines subject eligibility based on protocol Inclusion and Exclusion criteria.
- Demonstrate the informed consent process was correctly followed.
- Assures all human participant’s questions and concerns are addressed continuously throughout study participation in a timely fashion.
- Assesses subject participation at each protocol required visit (consent is a continual process).
- Properly identifies, documents and assist with Institutional Review Board (IRB) mandated reporting.
Provides Study Coordination as the primary CRC for a portfolio of clinical research studies varying in complexity, as well as back-up study coordinator for studies within assigned therapeutic area
- Screens, recruits, and manages retention of study participants.
- Conducts and documents informed consent process prior to any protocol required testing.
- Completes Case Report Forms (CRF) in a timely fashion and with accuracy.
- Maintains accurate test article accountability and reconciles as needed.
- Completes subject visit requirements per study protocol.
- Follows Food and Drug Administration (FDA) Regulations, Good Clinical Practice (GCP) guidelines, IRB Policies and Procedures.
- Follows Minneapolis Heart Institute Standard Operating Procedures (SOP) as well as abiding by Allina Health SOP requirements.
- Develops and maintains source and study documents for study lifecycle.
- Develops and ensures compliant processes with study protocols.
- Achieves enrollment goals accounting for variables beyond control.
- Supports planning, development and budgeting for clinical trials during study start-up as delegated by leadership.
Maintains Data Integrity
- Ensures adherence of MHIF Conflict of Interest (COI), confidentiality policies and Employee Code of Ethics.
- Resolves data queries per study timeline.
- Ensures accuracy of all study data abstracted from medical records and other sources.
Secondary Responsibilities
- Contributes to Research and/or MHIF organizational quality improvement initiatives as delegated by MHIF leadership.
- May contribute to dissemination of research by drafting text and/or charts for abstracts, manuscripts and poster/Power Point presentations.
- Manages other projects and completes various tasks as assigned by MHIF Leadership.
Relationships
This position reports to the Research Manager. The incumbent interacts regularly with other members of the Clinical Research team, Minneapolis Heart Institute (MHI) physicians, staff, patients, and study sponsors & vendors.
Core Values in Action
At MHIF, our values aren’t just words—they guide how we lead and work together:
- Integrity: Do the right thing, even when it’s hard. Operate ethically and transparently.
- Innovation: Ask bold questions. Be proactive and curious in improving how we work.
- Collaboration: Support one another, build trust, and celebrate success as one team.
- Excellence: Own your work. Be accountable. Bring urgency and resilience to solving problems.
What Sets You Apart
Required:
- CRC’s with experience are required to pass CCRC certification through the Association of Clinical Research Professionals (ACRP) or the Society of Clinical Research Associates (SOCRA) within two years of date of hire.
- A valid Minnesota Registered Nurse (RN) license.
- Bachelor’s degree.
- A minimum of 1 year clinical research coordination experience or equivalent combination of research and clinical experience.
- Proficiency in MS Office, MS Outlook and electronic medical record systems (Epic).
- Strong interpersonal skills with the ability to work with others as a team and in support of a positive work culture.
- Ability to work effectively managing multiple projects.
- Strong attention to detail.
- Must be able to pass institution’s compliance requirements, EMR (Epic) and Collaborative Institutional Training Initiative (CITI). (Incumbents assigned to National Institutes of Health (NIH) trials must be able to pass NIH mandated training prior to the start of the study.)
- Basic Life Support (BLS) certification.
Preferred:
- Previous cardiovascular clinical and/or research experience preferred.
- Experience with clinical trial management systems (CTMS) and document management systems.
- Active licensure via Diploma, Associate’s, or Bachelor’s degree programs in a healthcare-related field.
- NIHSS Certification.
Total Rewards
In addition to meaningful, mission-driven work, MHIF offers:
- Competitive salary range of $65,000 - $75,000.
Comprehensive benefits including:
- Medical, dental, and vision insurance.
- Life, short- and long-term disability.
- Employer HSA contribution.
- 401(k) with employer match and contribution.
- Generous PTO, paid holidays, and parental leave.
- Tuition reimbursement and paid volunteer time.
Why Join MHIF?
“Small team. Global impact.”
Here, your work has purpose. Your voice is heard. Your career can grow. We are driven by discovery and grounded in compassion—and we’re looking for someone who brings both heart and expertise to the table.
Ready to do work that matters?
Where Purpose Meets Progress
At the Minneapolis Heart Institute Foundation (MHIF), your dedication fuels innovation, transforms patient care, and helps shape the future of cardiovascular medicine. As a Research Nurse, your role goes beyond the bedside—you become a vital connection between patients and research that leads to life-saving discoveries.
Job Summary
In support of the Minneapolis Heart Institute Foundation (MHIF) mission, Clinical Research Coordinators (CRC) provide support, coordination and leadership for research studies that may involve industry sponsored Phase I, II, III, and IV clinical trials, drug, biologic, device, government-funded clinical research and investigator-initiated clinical research. They ensure smooth, accurate progress of clinical studies in accordance with all legal and regulatory standards from the planning and approval stages through study completion and post-study closure. CRC’s assist with documentation for Institutional Review Board (IRB) submissions, recruit and screen study participants and help facilitate their continued participation; abstract data from electronic medical records (EMR) and other sources; collect, submit and maintain study data and regulatory documents; ensure compliance with study protocols and participate in initial budget discussion for clinical trials.
Primary Responsibilities
Ensures Human Subject Protection
- Determines subject eligibility based on protocol Inclusion and Exclusion criteria.
- Demonstrate the informed consent process was correctly followed.
- Assures all human participant’s questions and concerns are addressed continuously throughout study participation in a timely fashion.
- Assesses subject participation at each protocol required visit (consent is a continual process).
- Properly identifies, documents and assist with Institutional Review Board (IRB) mandated reporting.
Provides Study Coordination as the primary CRC for a portfolio of clinical research studies varying in complexity, as well as back-up study coordinator for studies within assigned therapeutic area
- Screens, recruits, and manages retention of study participants.
- Conducts and documents informed consent process prior to any protocol required testing.
- Completes Case Report Forms (CRF) in a timely fashion and with accuracy.
- Maintains accurate test article accountability and reconciles as needed.
- Completes subject visit requirements per study protocol.
- Follows Food and Drug Administration (FDA) Regulations, Good Clinical Practice (GCP) guidelines, IRB Policies and Procedures.
- Follows Minneapolis Heart Institute Standard Operating Procedures (SOP) as well as abiding by Allina Health SOP requirements.
- Develops and maintains source and study documents for study lifecycle.
- Develops and ensures compliant processes with study protocols.
- Achieves enrollment goals accounting for variables beyond control.
- Supports planning, development and budgeting for clinical trials during study start-up as delegated by leadership.
Maintains Data Integrity
- Ensures adherence of MHIF Conflict of Interest (COI), confidentiality policies and Employee Code of Ethics.
- Resolves data queries per study timeline.
- Ensures accuracy of all study data abstracted from medical records and other sources.
Secondary Responsibilities
- Contributes to Research and/or MHIF organizational quality improvement initiatives as delegated by MHIF leadership.
- May contribute to dissemination of research by drafting text and/or charts for abstracts, manuscripts and poster/Power Point presentations.
- Manages other projects and completes various tasks as assigned by MHIF Leadership.
Relationships
This position reports to the Research Manager. The incumbent interacts regularly with other members of the Clinical Research team, Minneapolis Heart Institute (MHI) physicians, staff, patients, and study sponsors & vendors.
Core Values in Action
At MHIF, our values aren’t just words—they guide how we lead and work together:
- Integrity: Do the right thing, even when it’s hard. Operate ethically and transparently.
- Innovation: Ask bold questions. Be proactive and curious in improving how we work.
- Collaboration: Support one another, build trust, and celebrate success as one team.
- Excellence: Own your work. Be accountable. Bring urgency and resilience to solving problems.
What Sets You Apart
Required:
- CRC’s with experience are required to pass CCRC certification through the Association of Clinical Research Professionals (ACRP) or the Society of Clinical Research Associates (SOCRA) within two years of date of hire.
- A valid Minnesota Registered Nurse (RN) license.
- Bachelor’s degree.
- A minimum of 1 year clinical research coordination experience or equivalent combination of research and clinical experience.
- Proficiency in MS Office, MS Outlook and electronic medical record systems (Epic).
- Strong interpersonal skills with the ability to work with others as a team and in support of a positive work culture.
- Ability to work effectively managing multiple projects.
- Strong attention to detail.
- Must be able to pass institution’s compliance requirements, EMR (Epic) and Collaborative Institutional Training Initiative (CITI). (Incumbents assigned to National Institutes of Health (NIH) trials must be able to pass NIH mandated training prior to the start of the study.)
- Basic Life Support (BLS) certification.
Preferred:
- Previous cardiovascular clinical and/or research experience preferred.
- Experience with clinical trial management systems (CTMS) and document management systems.
- Active licensure via Diploma, Associate’s, or Bachelor’s degree programs in a healthcare-related field.
- NIHSS Certification.
Total Rewards
In addition to meaningful, mission-driven work, MHIF offers:
- Competitive salary range of $65,000 - $75,000.
Comprehensive benefits including:
- Medical, dental, and vision insurance.
- Life, short- and long-term disability.
- Employer HSA contribution.
- 401(k) with employer match and contribution.
- Generous PTO, paid holidays, and parental leave.
- Tuition reimbursement and paid volunteer time.
Why Join MHIF?
“Small team. Global impact.”
Here, your work has purpose. Your voice is heard. Your career can grow. We are driven by discovery and grounded in compassion—and we’re looking for someone who brings both heart and expertise to the table.
Ready to do work that matters?
See All 6 Clinical Research Nurse Jobs in Minnesota
Find roles in Minnesota that match your experience and apply in just a few clicks.
Find Clinical Research Nurse JobsClinical Research Nurse Jobs by City in Minnesota
Where Minnesota roles are concentrated, by current openings.
Clinical Research Nurse Job Market in Minnesota
A snapshot from current Minnesota openings, updated as new roles post.
Who's Hiring
- Allina Health2
- University of Minnesota2
- Mayo Clinic1
- Minneapolis Heart Institute Foundation1
Top Industries Hiring
- Healthcare & Medical Services4
- Education3
- Non-Profit & Social Services1
- Science & Research1
What Minnesota Employers Look For
The qualifications that appear most often in clinical research nurse jobs across Minnesota.
- Active RN license in the state of employment
- Minimum two years of clinical nursing experience in a relevant specialty
- Working knowledge of ICH-GCP guidelines and Good Clinical Practice standards
- Experience with electronic data capture systems such as Medidata Rave or REDCap
- CCRP or CCRC certification preferred or required by many employers
- Ability to obtain and maintain site-specific training and protocol certifications
Clinical Research Nurse Jobs in Minnesota: Frequently Asked Questions
How many clinical research nurse jobs are there in Minnesota?
There are 6+ clinical research nurse openings in Minnesota on Migrate Mate as of June 2026, with the most roles in Minneapolis and Rochester. New positions post regularly as employers across Minnesota hire.
Which Minnesota cities have the most clinical research nurse jobs?
Minneapolis and Rochester have the most clinical research nurse openings in Minnesota right now, with additional roles spread across smaller metros statewide.
Which companies hire clinical research nurses in Minnesota?
Employers hiring clinical research nurses in Minnesota include Allina Health, University of Minnesota, and Mayo Clinic, based on current listings on Migrate Mate as of June 2026.
Are there remote clinical research nurse jobs in Minnesota?
Yes. About 17% of clinical research nurse openings tied to Minnesota are remote or hybrid as of June 2026. The rest are on-site roles based in Minnesota metros.
How do I apply for clinical research nurse jobs in Minnesota?
You can apply to clinical research nurse jobs in Minnesota directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Minnesota location, then apply to each one that fits.
See All 6 Clinical Research Nurse Jobs in Minnesota
Find roles in Minnesota that match your experience and apply in just a few clicks.
Find Clinical Research Nurse Jobs