Clinical Research Nurse Jobs in Minnesota

Clinical Research Nurse jobs in Minnesota concentrate in academic medical centers, large integrated health systems, and pharmaceutical and medical device companies, reflecting the state's dense life sciences corridor. Most hiring activity is in Minneapolis, Rochester, and Saint Paul, where employers such as Mayo Clinic, M Health Fairview, and Allina Health maintain sustained clinical trial programs. Oncology, cardiology, and neurology trials draw the steadiest demand, with openings at every experience level from entry-level coordinators to senior principal investigators. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles30
Top employerUniversity of Minnesota
Top cityMinneapolis, MN
Cities hiring10
Work type47% On-site
Top industryEducation

Showing 5 of 30+ Clinical Research Nurse jobs

Medtronic
Clinical Research Spec
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Medtronic
New 7h ago
Clinical Research Spec
Medtronic
Mounds View, Minnesota
Cybersecurity
Security Engineering
Technical Program Management
$83k - $125k/yr
Remote (US)
Bachelor's degree in engineering
10,000+

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Medtronic
Clinical Research Specialist
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Medtronic
New 13h ago
Clinical Research Specialist
Medtronic
Mounds View, Minnesota
Business Operations
Business Strategy
Consulting & Professional Services
$83k - $125k/yr
Bachelor's degree
10,000+

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Mayo Clinic
Associate Clinical Research Coordinator - Comprehensive Cancer Center
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Mayo Clinic
Added 1d ago
Associate Clinical Research Coordinator - Comprehensive Cancer Center
Mayo Clinic
Rochester, Minnesota
Biotech & Life Sciences
Clinical Trials
Research & Academia
$24.55 - $35.65/hr
Hybrid
High school diploma or GED
10,000+

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University of Minnesota
50% Senior Clinical Research Quality Assurance Analyst
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University of Minnesota
Added 2d ago
50% Senior Clinical Research Quality Assurance Analyst
University of Minnesota
Minneapolis, Minnesota
Clinical Trials & Medical Research
Data Analytics
Data Science
Hybrid
Bachelor of Science
10,000+

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US Department of Veterans Affairs
Physician - Geriatric Research, Education and Clinical Center (GRECC) Clinician Investigator
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US Department of Veterans Affairs
Added 2d ago
Physician - Geriatric Research, Education and Clinical Center (GRECC) Clinician Investigator
US Department of Veterans Affairs
Minneapolis, Minnesota
Business Development
Events & Tourism
Executive Leadership & C-Suite
Project Management
$250k - $315k/yr
On-Site
Military encouraged
10,000+

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See All 30 Clinical Research Nurse Jobs in Minnesota

Find roles in Minnesota that match your experience and apply in just a few clicks.

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Clinical Research Nurse Jobs by City in Minnesota

Where Minnesota roles are concentrated, by current openings.

Minneapolis
11 jobs
Rochester
7 jobs
Minnetonka
2 jobs
Mounds View
2 jobs
Eagan
1 job
Edina
1 job
Richfield
1 job
Saint Paul
1 job
Maple Grove
1 job

Clinical Research Nurse Job Market in Minnesota

A snapshot from current Minnesota openings, updated as new roles post.

Who's Hiring

University of Minnesota
University of Minnesota9 open roles
Mayo Clinic
Mayo Clinic6 open roles
Medtronic
Medtronic2 open roles

Top Industries Hiring

  • Education
  • Medical Devices
  • Distribution & Wholesale

What Minnesota Employers Look For

The qualifications that appear most often in clinical research nurse jobs across Minnesota.

  • Active registered nurse license issued or recognized by the Minnesota Board of Nursing
  • Bachelor of Science in Nursing or higher from an accredited program
  • One or more years of clinical nursing experience in a hospital or research setting
  • Certification as a Clinical Research Professional through ACRP or SOCRA preferred
  • Demonstrated knowledge of Good Clinical Practice guidelines and ICH standards
  • Experience with electronic data capture systems such as REDCap or Medidata

Clinical Research Nurse Jobs in Minnesota: Frequently Asked Questions

How do you become a clinical research nurse in Minnesota?

You must first hold an active registered nurse license issued by the Minnesota Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN. From there, most Minnesota employers expect at least some bedside experience before moving into a research role. Earning a Clinical Research Professional credential through ACRP or SOCRA strengthens your application, and many candidates gain an edge by starting as a clinical research coordinator at a major academic or health system site.

Which companies hire clinical research nurses in Minnesota?

Minnesota clinical research nurse roles are posted by University of Minnesota, Mayo Clinic, and Medtronic and others right now, based on current listings on Migrate Mate as of August 2026. Minnesota's deep network of academic medical centers, integrated health systems, and medical device companies means sustained hiring across a range of therapeutic areas and trial phases.

Which Minnesota cities have the most clinical research nurse jobs?

Minneapolis, Rochester, and Minnesota have the most clinical research nurse openings in Minnesota. Minneapolis anchors the market as home to large health systems and a growing biotech cluster, while Rochester draws consistent volume from Mayo Clinic's extensive clinical trials enterprise, and smaller suburban and secondary markets benefit from satellite campuses and community research sites operated by those same major employers.

Are there remote clinical research nurse jobs in Minnesota?

Yes, but they're rare. About 53% of clinical research nurse openings tied to Minnesota are remote or hybrid as of August 2026, reflecting the hands-on patient contact most trial roles require. The portions of the work most suited to remote arrangements include protocol review, regulatory documentation, data query resolution, and sponsor communication, rather than visit coordination or patient assessment.

How can I get hired as a clinical research nurse in Minnesota with little or no experience?

The most realistic entry path is applying for a clinical research coordinator or research assistant role at an academic medical center while you still hold an active Minnesota RN license. Mayo Clinic, M Health Fairview, and Allina Health each run structured research onboarding programs that accept candidates with limited trial experience. Moving laterally from a med-surg, oncology, or infusion unit gives you patient-interaction and documentation skills that research teams value, and completing a Good Clinical Practice training course before you apply gives your application a concrete edge.

Where can I find and apply to clinical research nurse jobs in Minnesota?

You can find and apply to clinical research nurse jobs in Minnesota on Migrate Mate, which lists current Minnesota openings across health systems, academic medical centers, and life sciences companies. Search the available roles, find the ones that match your experience and specialty area, and apply directly to the ones that fit.

See All 30 Clinical Research Nurse Jobs in Minnesota

Find roles in Minnesota that match your experience and apply in just a few clicks.

Find Clinical Research Nurse Jobs