Clinical Research Nurse Jobs in Minnesota
Clinical Research Nurse jobs in Minnesota concentrate in academic medical centers, large integrated health systems, and pharmaceutical and medical device companies, reflecting the state's dense life sciences corridor. Most hiring activity is in Minneapolis, Rochester, and Saint Paul, where employers such as Mayo Clinic, M Health Fairview, and Allina Health maintain sustained clinical trial programs. Oncology, cardiology, and neurology trials draw the steadiest demand, with openings at every experience level from entry-level coordinators to senior principal investigators. Scan the live roles below and apply to whichever ones fit.
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Job Title: Research Assistant I
Location: Minneapolis VA Medical Center
Job Code: CRAI, Full Time, Benefit Eligible, Non-Exempt
PI: Diane Mortimer/Casey Gilmore
Project: THIA/ReStart
Summary:
The Center for Veterans Research and Education (CVRE), whose mission is to help support
innovative research and education initiatives that improve the health and well-being of Veterans, is
seeking a Research Assistant.
Position Description:
The Research Assistant is responsible for assisting study investigators and coordinators with the conduct of interventional and observational research studies. Research involves the use of technology including transcranial direct current stimulation (tDCS), electroencephalography (EEG), and magnetic resonance imaging (MRI). This position will require working directly with clinical patients in a research capacity. Clinical populations include traumatic brain injury, substance use, chronic pain, and mood disorders.
Responsibilities:
Major duties and responsibilities may include, but are not limited to, the following:
- Assist with the execution of all aspects of research projects within the PI’s portfolio.
- Assist with recruitment, screening, and medical chart reviews.
- Conduct research study assessments in-person or over the telephone, in accordance with research protocols and standard operating procedures.
- Facilitate follow-up assessment reminders, scheduling, and participant payments.
- Perform data entry for research projects and maintain databases.
- Maintain testing supplies, files, and equipment in an organized manner.
- Maintain awareness of and compliance with research regulatory issues.
- Assist in the preparation of technical reports, summaries, and manuscripts (i.e., literature reviews, table preparation).
- Communicate regularly with study team, under the direction of project leaders, via email and conferencing.
- Maintain professional clearances/human studies training to be fully qualified to work with sensitive data as promulgated by the IRB, HIPAA, VHA, and other regulatory agencies.
- Assist with other research studies or lab duties, as directed by supervisor and as time allows.
Applicant must include a cover letter
Minimum Qualifications:
Education: Bachelor’s (BA/BS) or above from an accredited college or university in
public health, sociology, psychology, or related allied health field
Experience: 0-2 years of experience required for CRA I
2-4 years of experience required for CRA II
Licensure/Registration/Certification: None
Preferred Qualifications:
- Research Assistant experience dealing with data collection and data storage, human subject studies, and institutional review board processes.
- Knowledge of Good Clinical Practices, human subjects’ protections, and federal regulations related to clinical research.
Knowledge, Skills, and Abilities:
- Basic experience with trouble-shooting devices and software settings.
- Experience in coordinating multiple task and project elements with differing timelines and completion deadlines.
- Demonstrated ability to work effectively both independently and as part of a team.
- Excellent oral and written communication skills.
- Exceptional attention to detail and organizational skills.
- Proficiency in Microsoft Office products including Outlook, Word, PowerPoint, and Excel.
Conditions of Employment:
- Subject to a criminal and educational background check.
- Designated and/or random drug testing may be required.
- Regular and predictable attendance is required.
- Typical hours fall within standard business hours, work may be required during hours beyond standard business hours, including weekends.
- Must be a US citizen
Physical Requirements: The employee must be able to navigate the medical center, use a keyboard, and lift 25 lbs. Reasonable accommodation may be considered in determining an applicant’s ability to perform the duties/functions of the position.
See All 43 Clinical Research Nurse Jobs in Minnesota
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Find Clinical Research Nurse JobsClinical Research Nurse Jobs by City in Minnesota
Where Minnesota roles are concentrated, by current openings.
Clinical Research Nurse Job Market in Minnesota
A snapshot from current Minnesota openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Education
- Medical Devices
What Minnesota Employers Look For
The qualifications that appear most often in clinical research nurse jobs across Minnesota.
- Active registered nurse license issued or recognized by the Minnesota Board of Nursing
- Bachelor of Science in Nursing or higher from an accredited program
- One or more years of clinical nursing experience in a hospital or research setting
- Certification as a Clinical Research Professional through ACRP or SOCRA preferred
- Demonstrated knowledge of Good Clinical Practice guidelines and ICH standards
- Experience with electronic data capture systems such as REDCap or Medidata
Clinical Research Nurse Jobs in Minnesota: Frequently Asked Questions
How do you become a clinical research nurse in Minnesota?
You must first hold an active registered nurse license issued by the Minnesota Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN. From there, most Minnesota employers expect at least some bedside experience before moving into a research role. Earning a Clinical Research Professional credential through ACRP or SOCRA strengthens your application, and many candidates gain an edge by starting as a clinical research coordinator at a major academic or health system site.
Which companies hire clinical research nurses in Minnesota?
Minnesota clinical research nurse roles are posted by Mayo Clinic, Headlands Research, and University of Minnesota and others right now, based on current listings on Migrate Mate as of October 2026. Minnesota's deep network of academic medical centers, integrated health systems, and medical device companies means sustained hiring across a range of therapeutic areas and trial phases.
Which Minnesota cities have the most clinical research nurse jobs?
Minneapolis, Rochester, and Saint Paul have the most clinical research nurse openings in Minnesota. Minneapolis anchors the market as home to large health systems and a growing biotech cluster, while Rochester draws consistent volume from Mayo Clinic's extensive clinical trials enterprise, and smaller suburban and secondary markets benefit from satellite campuses and community research sites operated by those same major employers.
Are there remote clinical research nurse jobs in Minnesota?
Yes, but they're rare. About 65% of clinical research nurse openings tied to Minnesota are remote or hybrid as of October 2026, reflecting the hands-on patient contact most trial roles require. The portions of the work most suited to remote arrangements include protocol review, regulatory documentation, data query resolution, and sponsor communication, rather than visit coordination or patient assessment.
How can I get hired as a clinical research nurse in Minnesota with little or no experience?
The most realistic entry path is applying for a clinical research coordinator or research assistant role at an academic medical center while you still hold an active Minnesota RN license. Mayo Clinic, M Health Fairview, and Allina Health each run structured research onboarding programs that accept candidates with limited trial experience. Moving laterally from a med-surg, oncology, or infusion unit gives you patient-interaction and documentation skills that research teams value, and completing a Good Clinical Practice training course before you apply gives your application a concrete edge.
Where can I find and apply to clinical research nurse jobs in Minnesota?
You can find and apply to clinical research nurse jobs in Minnesota on Migrate Mate, which lists current Minnesota openings across health systems, academic medical centers, and life sciences companies. Search the available roles, find the ones that match your experience and specialty area, and apply directly to the ones that fit.
See All 43 Clinical Research Nurse Jobs in Minnesota
Find roles in Minnesota that match your experience and apply in just a few clicks.
Find Clinical Research Nurse Jobs