Compliance Specialist Jobs in South Carolina
Compliance Specialist jobs in South Carolina concentrate heavily in financial services, healthcare, and manufacturing, reflecting the state's anchoring industries and a market that runs from entry-level compliance analysts to senior regulatory affairs managers. Columbia, Greenville, and Charleston are the primary hiring centers, where employers such as BlueCross BlueShield of South Carolina, Michelin North America, and Bank of America maintain large compliance functions. The most in-demand specialties are healthcare regulatory compliance, financial services compliance, and environmental health and safety. Find a role that fits below and apply directly.
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Showing 5 of 6+ Compliance Specialist jobs
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The Senior Compliance Specialist is accountable for driving results in a fast-paced environment by effectively performing activities directed to ensure quality and compliance with applicable regulatory requirements. These activities may include reviewing documents and data, conducting audits and supporting inspections, and maintaining quality databases. The ideal candidate will assist with the development of SOPs or other quality documents as needed. The Senior Compliance Specialist will perform the role of Lead Inspector for external audits and act as consultant with clients for all levels of regulatory issues. The Sr. Compliance Specialist will provide guidance and mentoring for other compliance employees.
On-Site Expectations:- Hybrid position. Must be on-site for client audits. Occasional travel to other sites for audits.
- 1st Shift: Monday - Friday, 8:00am - 5:00pm.
- Host client audits and coordinate with clients.
- Coordinate with internal team members to complete responses.
- Write and coordinate audit responses.
- Perform quality review and approval of documents, data, protocols, and/or reports.
- May assist with supplier quality audits and/or inspections.
- May assist with evaluation of supplier changes and notifications and make assessment of impact accordingly.
- Maintain quality databases and support quality systems.
- Assist with development of SOPs or other quality documents as needed.
- Consult with clients on all levels of regulatory issues.
- Serve as an effective member of the Compliance team and serve as a mentor in area of expertise.
- Comply with company policies and SOPs.
- Assist with quality improvement initiatives as needed.
- Ensure timely completion and compliance with cGMP and all other relevant company training requirements.
- Other duties as assigned.
- Bachelor’s degree in Chemistry, Biology, or related field with 10+ years of GMP related experience, or Master’s degree in related field with 5+ years of related experience, or equivalent educational and work experience.
- Client hosting experience in the pharmaceutical industry preferred.
- Supplier management experience in pharmaceutical industry is a plus.
- Client-facing experience required.
- Strong knowledge of regulations and SOPs applicable to area of responsibility and keeps abreast of new regulations and regulatory guidance in areas of expertise.
- Good written and oral communication skills.
- Good computer skills and knowledge of Microsoft Office products.
- Ability to be trained and to mentor.
- Ability to interact well with employees at all levels.
- Ability to negotiate.
- Ability to lead audits.
- Ability to act as a consultant.
- Up to 10% travel for audits.
Are you interested in joining our team?
The Senior Compliance Specialist is accountable for driving results in a fast-paced environment by effectively performing activities directed to ensure quality and compliance with applicable regulatory requirements. These activities may include reviewing documents and data, conducting audits and supporting inspections, and maintaining quality databases. The ideal candidate will assist with the development of SOPs or other quality documents as needed. The Senior Compliance Specialist will perform the role of Lead Inspector for external audits and act as consultant with clients for all levels of regulatory issues. The Sr. Compliance Specialist will provide guidance and mentoring for other compliance employees.
On-Site Expectations:- Hybrid position. Must be on-site for client audits. Occasional travel to other sites for audits.
- 1st Shift: Monday - Friday, 8:00am - 5:00pm.
- Host client audits and coordinate with clients.
- Coordinate with internal team members to complete responses.
- Write and coordinate audit responses.
- Perform quality review and approval of documents, data, protocols, and/or reports.
- May assist with supplier quality audits and/or inspections.
- May assist with evaluation of supplier changes and notifications and make assessment of impact accordingly.
- Maintain quality databases and support quality systems.
- Assist with development of SOPs or other quality documents as needed.
- Consult with clients on all levels of regulatory issues.
- Serve as an effective member of the Compliance team and serve as a mentor in area of expertise.
- Comply with company policies and SOPs.
- Assist with quality improvement initiatives as needed.
- Ensure timely completion and compliance with cGMP and all other relevant company training requirements.
- Other duties as assigned.
- Bachelor’s degree in Chemistry, Biology, or related field with 10+ years of GMP related experience, or Master’s degree in related field with 5+ years of related experience, or equivalent educational and work experience.
- Client hosting experience in the pharmaceutical industry preferred.
- Supplier management experience in pharmaceutical industry is a plus.
- Client-facing experience required.
- Strong knowledge of regulations and SOPs applicable to area of responsibility and keeps abreast of new regulations and regulatory guidance in areas of expertise.
- Good written and oral communication skills.
- Good computer skills and knowledge of Microsoft Office products.
- Ability to be trained and to mentor.
- Ability to interact well with employees at all levels.
- Ability to negotiate.
- Ability to lead audits.
- Ability to act as a consultant.
- Up to 10% travel for audits.
See All 6 Compliance Specialist Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Compliance Specialist JobsCompliance Specialist Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Compliance Specialist Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Alcami1
- Nordson1
- Attain Finance1
- TOWN OF MOUNT PLEASANT1T
- AgFirst Farm Credit Bank1
Top Industries Hiring
- Agriculture & Farming1
- Banking & Financial Services1
What South Carolina Employers Look For
The qualifications that appear most often in compliance specialist jobs across South Carolina.
- Bachelor's degree in business, law, finance, or a related field required
- Certified Compliance and Ethics Professional (CCEP) credential preferred or required
- Working knowledge of applicable federal and South Carolina state regulations
- Three or more years of compliance, audit, or regulatory affairs experience
- Proficiency with compliance management software and case documentation systems
- Strong written communication skills for preparing regulatory reports and policies
Compliance Specialist Jobs in South Carolina: Frequently Asked Questions
How do you become a compliance specialist in South Carolina?
Most compliance specialist roles in South Carolina require a bachelor's degree in business, finance, law, or a related field, followed by experience in a regulated industry such as healthcare or financial services. South Carolina does not issue a general state license for compliance specialists, but employers strongly favor candidates who hold the Certified Compliance and Ethics Professional (CCEP) designation or a comparable credential from the Society of Corporate Compliance and Ethics. Healthcare-focused roles may also look for familiarity with South Carolina Department of Health and Environmental Control regulations.
How much do compliance specialists make in South Carolina?
Compliance specialists in South Carolina earn a median of about $86,440 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $52,530 for the lowest 10% to over $164,260 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire compliance specialists in South Carolina?
Employers hiring compliance specialists in South Carolina right now include Alcami, Nordson, and Attain Finance, based on current listings on Migrate Mate as of July 2026. South Carolina's concentration of large insurers, automotive and tire manufacturers, and regional financial institutions means steady, recurring compliance hiring across Columbia, Greenville, and Charleston.
Which South Carolina cities have the most compliance specialist jobs?
Clinton, Columbia, and Greenwood have the most compliance specialist openings in South Carolina. Columbia leads because it is the state capital and home to BlueCross BlueShield of South Carolina and several state agency headquarters, while Greenville's manufacturing corridor anchors demand there, and Charleston's growing financial services and healthcare sector drives activity along the coast.
Are there remote compliance specialist jobs in South Carolina?
Yes, and more than many fields, because compliance work is largely desk-based, analytical, and documentation-driven. About 100% of compliance specialist openings tied to South Carolina are remote or hybrid as of July 2026, reflecting how well the role translates to distributed work arrangements. Positions focused on policy review, regulatory reporting, and compliance training are the most consistently offered on a remote basis.
How can I get hired as a compliance specialist in South Carolina with little or no experience?
The most realistic entry path is moving into compliance from a closely adjacent role such as audit coordinator, paralegal, quality assurance analyst, or regulatory affairs assistant with a South Carolina healthcare system or insurer. BlueCross BlueShield of South Carolina and Prisma Health both hire associates and entry-level compliance analysts who support audits and policy documentation. Earning the CCEP-I certification, which is designed for professionals early in their compliance careers, signals commitment and gives candidates a measurable edge over others applying from adjacent functions.
Where can I find and apply to compliance specialist jobs in South Carolina?
You can find and apply to compliance specialist jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Search the listings, find roles that match your background and target location, and apply directly.
See All 6 Compliance Specialist Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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