Department Manager Jobs in South Carolina

Department Manager jobs in South Carolina concentrate heavily in retail, manufacturing, healthcare, and distribution, reflecting the state's robust base of consumer goods operations, automotive suppliers, and regional hospital networks. Most hiring activity runs through Columbia, Charleston, and Greenville, where employers like Walmart, BMW Manufacturing, and Prisma Health maintain large operations that routinely need department-level leadership. Demand is strongest for managers with experience in operations, retail floor management, and supply chain oversight. See the openings below and apply to the ones that match your experience.

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Overview

Open roles39
Top employerMcDonald's
Top cityCharleston, SC
Cities hiring21
Work type75% On-site
Top industryHealthcare

Showing 5 of 39+ Department Manager jobs

UNIV - Finance Manager - Department of Medicine: Divisions of Cardiology & Endocrinology
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UNIV - Finance Manager - Department of Medicine: Divisions of Cardiology & Endocrinology
Medical University of South Carolina
Charleston, South Carolina
Business Development
Executive Leadership & C-Suite
Partnerships & Business Development
$68k - $122k/yr
Master's degree
10,000+

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Assistant Department Manager (Tile)
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Added 2d ago
Assistant Department Manager (Tile)
Floor & Decor
Mount Pleasant, South Carolina
Customer Service
Retail Banking & Branch Management
Sales
High school diploma or GED
10,000+

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UNIV - Accounting/Fiscal Manager I - Department of Neuroscience
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Added 1w ago
UNIV - Accounting/Fiscal Manager I - Department of Neuroscience
Medical University of South Carolina
Charleston, South Carolina
Corporate Training
Learning & Development
Project Management
$68k - $122k/yr
Bachelor's degree
10,000+

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Department Manager - Low Voltage Cabling
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Added 1w ago
Department Manager - Low Voltage Cabling
IES Communications
Aiken, South Carolina
Construction Management
Program Management
Project Management
High school diploma or GED
51-200

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Department Manager - Gaffney
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Added 1w ago
Department Manager - Gaffney
NIKE
Gaffney, South Carolina
Business Development
Customer Success
Program Management
Project Management
10,000+

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See All 39 Department Manager Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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Department Manager Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Charleston
6 jobs
Mount Pleasant
5 jobs
North Charleston
5 jobs
Greenville
4 jobs
Rock Hill
2 jobs
Aiken
1 job
Greer
1 job
Seneca
1 job
Clemson
1 job

Department Manager Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • McDonald's12
  • Floor & Decor6
  • Medical University of South Carolina6
  • Whole Foods Market4
  • Pet Supplies Plus3

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in department manager jobs across South Carolina.

  • Bachelor's degree in business, management, or a related field preferred by most South Carolina employers
  • Minimum three to five years of supervisory or team lead experience in a relevant department
  • Demonstrated ability to manage budgets, schedules, and performance metrics for a department
  • Proficiency with inventory management, point-of-sale, or enterprise resource planning software
  • Strong communication skills to coordinate with frontline staff, vendors, and senior leadership
  • Familiarity with South Carolina labor regulations, workplace safety standards, and OSHA compliance

Department Manager Jobs in South Carolina: Frequently Asked Questions

How do you become a department manager in South Carolina?

Most department manager roles in South Carolina do not require a state-issued license, but employers consistently expect a bachelor's degree in business, operations, or a field related to the department alongside several years of frontline or supervisory experience. Starting as a team lead or assistant manager at a retailer, manufacturer, or healthcare facility in Columbia, Charleston, or Greenville is the most common path. Completing a management development program offered by larger South Carolina employers accelerates promotion to a full department manager title.

Which companies hire department managers in South Carolina?

South Carolina department manager roles are posted by McDonald's, Floor & Decor, and Medical University of South Carolina and others right now, based on current listings on Migrate Mate as of November 2026. South Carolina's mix of large retail chains, automotive manufacturers, and regional healthcare systems means department manager openings appear across a wide range of industries throughout the state.

Which South Carolina cities have the most department manager jobs?

Charleston, Mount Pleasant, and North Charleston currently have the most department manager openings in South Carolina. Columbia drives volume as the state capital and home to major retail corridors and healthcare systems like Prisma Health, Charleston's growing logistics and hospitality sectors add consistent demand, and Greenville's manufacturing base anchored by BMW and Michelin keeps operations-focused department manager roles active year-round.

Are there remote department manager jobs in South Carolina?

Yes, but they're rare. Department manager roles are typically hands-on positions requiring direct oversight of staff, inventory, or production floors, which limits remote options by nature. About 25% of department manager openings tied to South Carolina are remote or hybrid as of November 2026, and those tend to involve administrative or project-based functions rather than day-to-day floor management. Hybrid arrangements are most common in corporate operations or regional support roles.

How can I get hired as a department manager in South Carolina with little or no experience?

The most realistic entry path is starting in an assistant manager, team lead, or shift supervisor role at one of South Carolina's large retailers, distribution centers, or healthcare facilities and building a record of managing people and processes. Employers like Walmart, Target, and major distribution hubs in the Upstate region run structured management trainee programs that move high-performing associates into department manager seats. A relevant degree or coursework in business operations, combined with any people-management experience, gives candidates a clear edge when applying.

Where can I find and apply to department manager jobs in South Carolina?

You can find and apply to department manager jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, review the ones that fit your background and location, and apply directly to the positions that match your experience and career goals.

See All 39 Department Manager Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Department Manager Jobs