Key Account Manager Jobs in North Carolina
Key Account Manager jobs in North Carolina represent one of the more active markets in the Southeast, with consistent demand across technology, life sciences, financial services, and manufacturing sectors and openings from entry-level associate positions through senior and director-level roles. Charlotte, Raleigh-Durham, and Greensboro account for the largest share of listings, with established employers like Lowe's, Bank of America, and Red Hat regularly seeking key account managers to manage enterprise and mid-market relationships. The most in-demand specialties are SaaS and technology sales, healthcare and pharma accounts, and financial services client management. Find a role that fits below and apply directly.
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HOW MIGHT YOU DEFY IMAGINATION?
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Live
What you will do
The Rare Disease Key Account Manager’s overall goal is to reduce time to diagnosis, increase appropriate patient identification and improve speed to treatment by partnering with key stakeholders in targeted accounts through focus in the therapeutic areas that Amgen's Rare Disease products are indicated. The Rare Disease Key Account Manager (KAM) is responsible for unlocking operational and access challenges related to appropriate therapies across assigned health systems, specialty clinics, infusion centers, and sites of care to grow the overall rare disease business in the assigned accounts and market. The KAM diagnoses account-level barriers and executes targeted strategies that enable appropriate access to therapy, strengthen clinic readiness, optimize buy-and-bill operations, and support a reliable patient and customer experience across the rare disease treatment journey.
Responsibilities:
Account Strategy & Enterprise Value
- Proactively assess the business environment across assigned accounts to identify access, operational, economic, and care-delivery barriers that affect appropriate rare disease therapy utilization, reducing time to diagnosis and time to treatment .
- Develop and execute account plans and identify Amgen portfolio objectives aligned to customer priorities, including addressing portfolio growth, patient access, site-of-care friction, and treatment continuity.
- Build stakeholder maps and engage clinical leaders, administrators, pharmacy, finance, revenue cycle, procurement, infusion operations, and care coordinators through proactive calls with key stakeholders
- Translate account data and insights into clear opportunity hypotheses, action plans, and performance reviews of sites.
Clinic Contracting & Access
- Serve as the commercial lead for assigned account contracting opportunities, coordinating internal approvals and supporting compliant negotiation and execution.
- Identify and address barriers related to contracting, customer membership, ordering, distribution channel, formulary or pathway decisions, and product availability.
- Partner with market access, pricing, trade, reimbursement, and legal/compliance colleagues to support durable access solutions.
- Support account business reviews that assess contract performance, patient access, operational readiness, and appropriate commercial opportunities.
Buy-and-Bill Optimization & Site Enablement
- Evaluate buy-and-bill workflows, including acquisition, inventory, benefit verification, prior authorization, coding, billing, payment, and financial risk points.
- Work with clinics and internal partners to identify practical improvements in reimbursement readiness, inventory practices, ordering processes, and patient financial navigation.
- Engage sites of care through education, workflow support, and coordinated resources that strengthen readiness to initiate and maintain therapy.
- Help customers diagnose and identify operational gaps that can delay treatment, including referral handoffs, scheduling, infusion capacity, care coordination, and post-initiation follow-up.
Cross-Functional Leadership & Insights
- Coordinate field execution with sales, medical, patient services, market access, trade, analytics, and brand partners.
- Provide timely, actionable field insights into customer needs, competitive dynamics, reimbursement trends, and operational barriers with matrix colleagues.
- Monitor account performance and adapt priorities to deliver against agreed objectives in a compliant manner.
- Maintain accurate account plans, account affiliations, activity records, and opportunity documentation in required systems.
- Lead matrix planning and follow-through for priority account initiatives, clarifying partner roles, decision points, owners, and timelines.
Win
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a person with these qualifications.
Basic Qualifications
Doctorate degree and 2 years of sales experience and/or related account management experience
OR
Master’s degree and 4 years of sales experience and/or related account management experience
OR
Bachelor’s degree and 6 years of sales experience and/or related account management experience
OR
Associate’s degree and 10 years of sales experience and/or related account management experience
OR
High School diploma/GED and 12 years of sales experience and/or related account management experience
Preferred Qualifications:
- Experience working with complex provider accounts, specialty clinics, health systems, infusion centers, or similar sites of care.
- Experience in rare disease, specialty therapeutics, biologics, infusion, or other complex buy-and-bill environments.
- Demonstrated knowledge of reimbursement, coding, benefit verification, prior authorization, and clinic revenue-cycle considerations.
- Prior contracting, account negotiation, or experience with IDNs, GPOs, specialty pharmacies, distributors, or alternate sites of care.
- Understanding of clinic operations and site-of-care decision drivers.
- Strong business acumen and ability to interpret account economics, reimbursement information, and performance data.
- Executive communication, problem solving, and influence skills across clinical and administrative stakeholders.
- Ability to manage competing priorities, operate independently, and execute through cross-functional teams.
- A patient-centered, compliant approach to customer engagement and solution development.
Travel Requirements
- Approximately 40 – 60% travel within an assigned geography, including customer meetings, internal planning, and industry events.
Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.
In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
- Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans and bi-annual company-wide shutdowns
- Flexible work models, including remote work arrangements, where possible
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
Application deadline
Amgen's application deadline is 11/30 for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
See All 24 Key Account Manager Jobs in North Carolina
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Find Key Account Manager JobsKey Account Manager Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Key Account Manager Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Manufacturing
What North Carolina Employers Look For
The qualifications that appear most often in key account manager jobs across North Carolina.
- Bachelor's degree in business, marketing, or a related field required by most employers
- Three or more years of B2B sales or account management experience in a relevant industry
- Demonstrated ability to manage a defined book of business and hit revenue targets
- Proficiency with CRM platforms such as Salesforce or HubSpot to manage pipelines
- Strong presentation and negotiation skills for executive-level client engagements
- Experience coordinating cross-functional teams including sales, operations, and customer success
Key Account Manager Jobs in North Carolina: Frequently Asked Questions
How do you become a key account manager in North Carolina?
Most key account manager roles in North Carolina require a bachelor's degree in business, marketing, communications, or a closely related field, though some employers accept equivalent experience. There is no state-issued license or registration for this role in North Carolina. Employers typically expect a background in B2B sales or client services, and candidates who can demonstrate a history of managing enterprise accounts in technology, life sciences, or financial services are the strongest applicants in this market.
How much do key account managers make in North Carolina?
Key account managers in North Carolina earn a median of about $70,990 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $38,200 for the lowest 10% to over $144,310 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire key account managers in North Carolina?
Employers hiring key account managers in North Carolina right now include Amgen, Innerspace, and Syneos Health Commercial Solutions, based on current listings on Migrate Mate as of November 2026. North Carolina's concentration of technology companies in the Research Triangle and large financial institutions in Charlotte means demand is particularly consistent in those two metro areas.
Which North Carolina cities have the most key account manager jobs?
Charlotte, Raleigh, and Burlington have the most key account manager openings in North Carolina. Charlotte drives volume through its large financial services, logistics, and corporate headquarters presence, while Raleigh and Durham benefit from the Research Triangle's dense cluster of technology, pharmaceutical, and enterprise software companies that rely heavily on dedicated account management teams.
Are there remote key account manager jobs in North Carolina?
Yes, and more than most fields. About 100% of key account manager openings tied to North Carolina are remote or hybrid as of November 2026, reflecting how much of the role centers on calls, video meetings, and CRM work rather than daily on-site presence. Strategic account planning, reporting, and internal coordination are the functions most commonly performed remotely, though travel for key client visits is still expected in most roles.
How can I get hired as a key account manager in North Carolina with little or no experience?
The most realistic entry path is moving into a junior account manager or sales development representative role at a mid-size technology or healthcare company in the Raleigh-Durham or Charlotte market, where growth-stage firms regularly hire candidates without extensive account management history. Roles like inside sales representative, customer success associate, or business development coordinator at companies in the Research Triangle Park corridor are common stepping stones. Earning a Salesforce certification or completing a relevant business certification through a University of North Carolina system program gives candidates a concrete edge when competing against more experienced applicants.
Where can I find and apply to key account manager jobs in North Carolina?
You can find and apply to key account manager jobs in North Carolina on Migrate Mate, which lists current openings from employers hiring in the state right now. Search the listings to find roles that match your experience and target industry, then apply directly to the ones that fit.
See All 24 Key Account Manager Jobs in North Carolina
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