Safety Manager Jobs in California
Safety Manager jobs in California are among the most active in the country, with consistent demand across construction, manufacturing, logistics, and tech, at every level from entry-level safety coordinator through senior environmental health and safety director. The heaviest hiring concentrates in Los Angeles, the San Francisco Bay Area, and San Diego, where employers such as Chevron, Kaiser Permanente, and Amazon operate large facilities with dedicated safety teams. Construction site safety, process safety management, and CalOSHA compliance are the most in-demand specialties across the state. Find a role that fits below and apply directly.
Find Safety Manager JobsOverview
Showing 5 of 240+ Safety Manager jobs
The Manager, Safety Quality and Compliance - Contractor will be responsible for supporting the development, management and oversight of processes, systems and PV inspection preparedness activities pertaining to safety and pharmacovigilance to ensure PV compliance with global regulations. This role will be key in contributing to process improvement, inspection readiness, internal/partner audits, and global regulatory inspections to drive compliance, building training models, supporting PV related agreements. This role also includes partnering with PV Operations to provide safety operations support as needed, manage and monitor internal PV activities and external oversight of CROs and vendors providing PV related services to Arcus.
Core Tasks Support:
Process Improvement and Gap Analysis
- Support impact assessment of existing PV processes when there are changes to regulatory requirements and support implementation of changes as applicable.
- Collaborate on the preparation and revision of Standard Operating Procedures (SOPs), Work Instructions (WI) and project plan to support process development and improvement.
- Coordinate document review with applicable internal and external stakeholders and follow up as needed for timely completion
Support Authorship and Management of PV Agreements
- Support the preparation (authoring), implementation and compliance oversight for safety data exchange agreements (SDEA)/PV agreements (PVA), including contracts with safety reporting.
Vendor oversight
- Partner with PV Operations to provide vendor management and oversight activities to ensure inspection preparedness.
Audit and Inspection:
- Demonstrate experience of leading/co-leading PV audits and inspections for the PS&PV department and in partnership with Quality organization.
- Conduct audit/inspection readiness activity and risk assessment, including development of storyboards, process mapping
- Work closely with the department leads to serving as a subject matter expert for internal and partner audits and global regulatory inspections
- Prepare/review audit/inspection agenda and plan
- Own the process of monitoring action items for all stakeholders involved in a PV audit/inspection and follow up for timely completion.
Project Management
- Support project management and organizational activities on departmental initiatives and projects
- Manage and support preparation of meetings, agenda, minutes, action items to drive results and efficiencies
Compliance Metrics / Key Performance Indicators (KPI)
- Collating PV compliance reports of KPIs/metrics using dashboards, excel, presentation, etc.
- Maintain monthly dashboard – case volume, submissions volume and submissions compliance data populated for pivot and presentation formats.
- Review metrics reports from multiple CROs and the safety vendor. Identify discrepancies and work with responsible stakeholders to resolve the issues.
- Ensure timely receipt of reports and follow up as needed.
- Maintain list of all the discrepancies and issues with the incoming metrics reports.
- Review incoming partner late cases and request late reason/CAPA. Escalate any trends if noted.
- Partner with internal cross-functional SMEs and external stakeholders like CROs and vendors to manage quality events/deviations and CAPA activities related to late safety reporting, process deviations and non-compliance issues.
- Initiate, investigate and complete internal deviations in Veeva. This includes collaboration with multiple stakeholders and receiving input, conflict resolution.
Safety Training:
- As needed, provide support to tracking and oversight of training assignments, compliance dashboard/status reports, review of training curriculum.
- Bachelor’s degree in nursing, pharmacy, or other health care related fields.
- 4+ years in the pharmaceutical industry setting; 2+ years’ experience working in Safety and Pharmacovigilance, specifically within quality and compliance.
- Oncology experience is required
- Extensive experience in safety quality systems, compliance monitoring, and the development and maintenance of standards and training programs.
- Strong knowledge and experience with available drug safety database systems, document management systems, QC tools, as well as MedDRA.
- Expert knowledge of FDA, EMA, Asia-PAC, and ICH regulations and guidelines.
- Demonstrated strategic problem-solving and critical thinking skills.
- Excellent interpersonal, communication, analytical, and organizational skills.
- Demonstrated ability to work effectively in a dynamic, complex, and fast-paced team environment.
- Track record of strong personal performance combined with demonstrated ability to build and lead high performing teams.
- Strong people and project management experience
- Strong cross-functional skills and a desire to help the team meet fast-paced growth into global territories and be self-motivated
#LI-Remote
#LI-JS1
The Manager, Safety Quality and Compliance - Contractor will be responsible for supporting the development, management and oversight of processes, systems and PV inspection preparedness activities pertaining to safety and pharmacovigilance to ensure PV compliance with global regulations. This role will be key in contributing to process improvement, inspection readiness, internal/partner audits, and global regulatory inspections to drive compliance, building training models, supporting PV related agreements. This role also includes partnering with PV Operations to provide safety operations support as needed, manage and monitor internal PV activities and external oversight of CROs and vendors providing PV related services to Arcus.
Core Tasks Support:
Process Improvement and Gap Analysis
- Support impact assessment of existing PV processes when there are changes to regulatory requirements and support implementation of changes as applicable.
- Collaborate on the preparation and revision of Standard Operating Procedures (SOPs), Work Instructions (WI) and project plan to support process development and improvement.
- Coordinate document review with applicable internal and external stakeholders and follow up as needed for timely completion
Support Authorship and Management of PV Agreements
- Support the preparation (authoring), implementation and compliance oversight for safety data exchange agreements (SDEA)/PV agreements (PVA), including contracts with safety reporting.
Vendor oversight
- Partner with PV Operations to provide vendor management and oversight activities to ensure inspection preparedness.
Audit and Inspection:
- Demonstrate experience of leading/co-leading PV audits and inspections for the PS&PV department and in partnership with Quality organization.
- Conduct audit/inspection readiness activity and risk assessment, including development of storyboards, process mapping
- Work closely with the department leads to serving as a subject matter expert for internal and partner audits and global regulatory inspections
- Prepare/review audit/inspection agenda and plan
- Own the process of monitoring action items for all stakeholders involved in a PV audit/inspection and follow up for timely completion.
Project Management
- Support project management and organizational activities on departmental initiatives and projects
- Manage and support preparation of meetings, agenda, minutes, action items to drive results and efficiencies
Compliance Metrics / Key Performance Indicators (KPI)
- Collating PV compliance reports of KPIs/metrics using dashboards, excel, presentation, etc.
- Maintain monthly dashboard – case volume, submissions volume and submissions compliance data populated for pivot and presentation formats.
- Review metrics reports from multiple CROs and the safety vendor. Identify discrepancies and work with responsible stakeholders to resolve the issues.
- Ensure timely receipt of reports and follow up as needed.
- Maintain list of all the discrepancies and issues with the incoming metrics reports.
- Review incoming partner late cases and request late reason/CAPA. Escalate any trends if noted.
- Partner with internal cross-functional SMEs and external stakeholders like CROs and vendors to manage quality events/deviations and CAPA activities related to late safety reporting, process deviations and non-compliance issues.
- Initiate, investigate and complete internal deviations in Veeva. This includes collaboration with multiple stakeholders and receiving input, conflict resolution.
Safety Training:
- As needed, provide support to tracking and oversight of training assignments, compliance dashboard/status reports, review of training curriculum.
- Bachelor’s degree in nursing, pharmacy, or other health care related fields.
- 4+ years in the pharmaceutical industry setting; 2+ years’ experience working in Safety and Pharmacovigilance, specifically within quality and compliance.
- Oncology experience is required
- Extensive experience in safety quality systems, compliance monitoring, and the development and maintenance of standards and training programs.
- Strong knowledge and experience with available drug safety database systems, document management systems, QC tools, as well as MedDRA.
- Expert knowledge of FDA, EMA, Asia-PAC, and ICH regulations and guidelines.
- Demonstrated strategic problem-solving and critical thinking skills.
- Excellent interpersonal, communication, analytical, and organizational skills.
- Demonstrated ability to work effectively in a dynamic, complex, and fast-paced team environment.
- Track record of strong personal performance combined with demonstrated ability to build and lead high performing teams.
- Strong people and project management experience
- Strong cross-functional skills and a desire to help the team meet fast-paced growth into global territories and be self-motivated
#LI-Remote
#LI-JS1
See All 240+ Safety Manager Jobs in California
Find roles in California that match your experience and apply in just a few clicks.
Find Safety Manager JobsSafety Manager Jobs by City in California
Where California roles are concentrated, by current openings.
Safety Manager Job Market in California
A snapshot from current California openings, updated as new roles post.
Who's Hiring
- TikTok15
- Meta6
- MV Transportation6
- Transdev5
- Apple4
Top Industries Hiring
- Technology & Software19
- Construction & Real Estate11
- Transportation & Logistics8
- Consulting & Professional Services6
- Automotive4
What California Employers Look For
The qualifications that appear most often in safety manager jobs across California.
- Current Certified Safety Professional (CSP) credential recognized under California hiring standards
- Demonstrated knowledge of CalOSHA Title 8 regulations and compliance requirements
- Bachelor's degree in occupational health, environmental science, or a related field
- Experience conducting workplace hazard assessments, audits, and incident investigations
- Ability to develop and deliver safety training programs for diverse workforces
- Proficiency with OSHA recordkeeping, injury reporting, and workers' compensation coordination
Safety Manager Jobs in California: Frequently Asked Questions
How do you become a safety manager in California?
Most safety manager roles in California require a bachelor's degree in occupational safety, environmental health, or a related field, combined with field experience in a safety coordinator or specialist role. California employers strongly favor candidates who hold the Certified Safety Professional (CSP) credential through the Board of Certified Safety Professionals. Familiarity with CalOSHA Title 8 standards is treated as a baseline requirement in most industries, so grounding yourself in those regulations early gives you a clear advantage in the hiring process.
How much do safety managers make in California?
Safety managers in California earn a median of about $102,840 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $59,760 for the lowest 10% to over $161,300 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire safety managers in California?
Employers hiring safety managers in California right now include TikTok, Meta, and MV Transportation, based on current listings on Migrate Mate as of August 2026. California's mix of large construction contractors, major healthcare systems, and manufacturing and logistics operations means demand comes from a wide range of industries rather than clustering in a single sector.
Which California cities have the most safety manager jobs?
Los Angeles, San Francisco, and San Jose have the most safety manager openings in California. Los Angeles drives volume through its large construction, logistics, and entertainment production industries, the Bay Area through tech campuses and biotech facilities, and San Diego through defense contractors and life sciences employers, which means even cities outside the largest metros can show strong activity when a major facility or project is active nearby.
Are there remote safety manager jobs in California?
Yes, but they're rare. Safety management is inherently on-site work, with most responsibilities tied to physical inspections, hazard assessments, and direct workforce oversight that cannot be done remotely. About 22% of safety manager openings tied to California are remote or hybrid as of August 2026, and those positions tend to focus on program development, compliance documentation, or corporate EHS oversight rather than site-level management.
How can I get hired as a safety manager in California with little or no experience?
The most realistic entry path is a safety coordinator or safety specialist role, which large California construction firms, healthcare systems, and manufacturers regularly post as junior positions. CalOSHA's voluntary protection programs and large employers such as Kaiser Permanente and major general contractors often bring in associate-level safety staff who rotate through supervised site work. Completing a Cal/OSHA 30-hour outreach course and beginning the Associate Safety Professional (ASP) credential process signals seriousness to hiring managers, even before you hold a CSP.
Where can I find and apply to safety manager jobs in California?
You can find and apply to safety manager jobs in California on Migrate Mate, which lists current California openings updated regularly. Search by city or specialty to narrow results to roles that match your experience level and industry, then apply directly to the listings that fit.
See All 240+ Safety Manager Jobs in California
Find roles in California that match your experience and apply in just a few clicks.
Find Safety Manager Jobs