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Get Access To All JobsUniversity of Colorado Anschutz Medical Campus
Department: Orthopedics
Job Title: Laboratory Research Professional (Open Rank, Intermediate-Senior and Principal)
Position #: 00828755 – Requisition: 39137
Job Summary:
The Burger laboratory in the Colorado Program for Musculoskeletal Research, within the Department of Orthopedics, is seeking to fill the position of a Research Services Principal Professional. Candidates may also be considered at intermediate or senior level. In the Burger lab, we are interested in early vertebrate development of the axial and lateral plate mesoderm using zebrafish and mice as models, as well as associated structural birth defects, such as spina bifida, or defects affecting the heart/blood/bone/kidney. We are further interested in how the axial mesoderm develops into the intervertebral discs, and associated underlying molecular mechanisms, as well as intervertebral disc disease, such as IVD degeneration. The Research Services Principal Professional is expected to be the research lead for several ongoing projects, including design of experimental setup, data generation, and data interpretation, with the following key responsibilities:
- Perform molecular biology experiments and related animal work, including mouse husbandry, genotyping, tissue collection, see details below (~90% of work)
- Perform administrative tasks, see details below (~10% of work)
Key Responsibilities:
All Levels
- Collaborate with and support Principal Investigators (PI) and other stakeholders with laboratory and research functions
- Utilize a variety of laboratory techniques required for research projects
- Independently and creatively identify laboratory solutions
- Independently Review, develop and implement new or modified laboratory techniques required for research projects
- Assist Team Leads, Supervisors and/or management with creation and implementation of processes and procedures and quality improvement initiatives
- Assist and train junior team members.
Senior Level: All Duties listed above plus the following:
- Assist with developing or develop protocol-specific systems and documents including process flows, training manuals, and Standard Operating Procedures (SOPs). Maintains subject level documentation and prepares documents, equipment and/or supplies
- Assist with identifying issues related to operational efficiency and shares results with leadership
- Provide laboratory science expertise and leadership in study design, study oversight, data management, data analysis and manuscript preparation to assist all levels of investigators, researchers and clinicians on new research activities across a wide range of disciplines
- Serve as a resource to PIs and other stakeholders
Principal Level: All Duties listed above plus the following:
- Oversee and provide informal leadership to the team members including managing day-to-day priorities, evaluating and redistributing workloads on a temporary basis, and mentoring staff
- Provide input and feedback to leadership on team members overall performance, performance evaluations, opportunities for development, and process improvement initiatives
- Identify training and development opportunities for new and existing team members
- Act as a Subject Matter Expert and authority in the area(s) of zebrafish laboratory work and development of the spine.
Additional Duties & Responsibilities:
Wet lab key responsibilities:
- Conducting molecular biology experiments, such as, but not limited to: PCR, gateway cloning, restriction digest and T4 ligation, Sanger sequencing of plasmid vectors, RNA work, e.g. CRISPR guide RNA generation, mRNA generation, immunohistochemistry/fluorescence, Western blotting, RNA and genomic DNA collection from mouse for RNAseq and ATACseq experiments
- Work with different mouse mutant and transgenic strains, such as mouse husbandry/breeding, genotyping, dissection for tissue collection, e.g. spine, long bones, etc.
- Mouse skeletal and non-skeletal tissue harvest for histological analysis, including embedding, sectioning and imaging, and for RNA and genomic DNA preparation
Administrative responsibilities:
- Ordering consumables and materials, etc.
- Maintaining laboratory area and equipment in working and clean condition
- Contributing to animal protocol writing
- Handling EHS requirements
- Overseeing training from junior lab members
- Managing internal and external collaborations with key stakeholders
- Presentation of research findings, e.g. at department internal meetings, national and international scientific meetings
- Additional responsibilities related to position as assigned by PI
Work Location:
Onsite – this role is expected to work onsite and is located in Aurora, CO.
Why Join Us:
The University of Colorado, Department of Orthopedics is a recognized global leader in the field and Colorado's most trusted orthopedic group for adults and children. Our unique position at the forefront of medical science, education, and practice innovation translates in real-time to the most advanced patient care, unmatched in Colorado and the Rocky Mountain Region. From routine cases to the most complex, we treat every orthopedic condition including injuries and diseases of the bones, joints, nerves, tendons, ligaments, and muscles across many orthopedic specialties.
Why work for the University?
We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:
- Medical: Multiple plan options
- Dental: Multiple plan options
- Additional Insurance: Disability, Life, Vision
- Retirement 401(a) Plan: Employer contributes 10% of your gross pay
- Paid Time Off: Accruals over the year
- Vacation Days: 22/year (maximum accrual 352 hours)
- Sick Days: 15/year (unlimited maximum accrual)
- Holiday Days: 10/year
- Tuition Benefit: Employees have access to this benefit on all CU campuses
- ECO Pass: Reduced rate RTD Bus and light rail service
There are many additional perks & programs with the CU Advantage.
Minimum Qualifications:
Intermediate level:
- Bachelor’s degree in biology, molecular biology, chemistry, genetics or related field
- A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year for year basis
- One (1) year professional level wet lab research experience, including mouse work
Senior level:
- Bachelor’s degree in biology, molecular biology, chemistry, genetics or related field
- A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year for year basis
- Two (2) years professional level wet lab research experience, including mouse work
Principal level:
- Bachelor’s degree in biology, molecular biology, chemistry, genetics or related field
- A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year for year basis
- Three (3) years professional level wet lab research experience, including mouse work
Preferred Qualifications
- Master’s degree in biology, molecular biology, chemistry, genetics or related field
- Four (4) years of experience in an experimental or wet laboratory, including mouse work
- Prior experience with molecular biology methods including, but not limited to PCR, cloning, immunoprecipitation, microscopy, RNA in situ hybridization
How to Apply:
For full consideration, please submit the following document(s):
- A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
- Curriculum vitae / Resume
- Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address
Questions should be directed to: Alexa Burger, ALEXA.BURGER@CUANSCHUTZ.EDU.
Screening of Applications Begins:
Screening begins immediately and continues until position is filled. For best consideration, apply by March 27, 2026.
Anticipated Pay Range:
The starting salary range (or hiring range) for this position has been established as HIRING RANGE
- Intermediate: $50,357-$64,054
- Senior: $54,440-$69,248
- Principal: $62,606-$79,635
The above salary range (or hiring range) represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level. Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line. Total Compensation Calculator
Equal Employment Opportunity Statement:
CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.
ADA Statement:
The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.
Background Check Statement:
The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.
Vaccination Statement:
CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.
University Staff Job Category
Research Services
Primary Location
Aurora
Department
U0001 -- Anschutz Med Campus or Denver
Schedule
Full-time
Posting Date
Feb 25, 2026
Unposting Date
Ongoing
Posting Contact Name
Thomas Roller
Posting Contact Email
thomas.roller@cuanschutz.edu
Position Number
00828755
University of Colorado Anschutz Medical Campus
Department: Orthopedics
Job Title: Laboratory Research Professional (Open Rank, Intermediate-Senior and Principal)
Position #: 00828755 – Requisition: 39137
Job Summary:
The Burger laboratory in the Colorado Program for Musculoskeletal Research, within the Department of Orthopedics, is seeking to fill the position of a Research Services Principal Professional. Candidates may also be considered at intermediate or senior level. In the Burger lab, we are interested in early vertebrate development of the axial and lateral plate mesoderm using zebrafish and mice as models, as well as associated structural birth defects, such as spina bifida, or defects affecting the heart/blood/bone/kidney. We are further interested in how the axial mesoderm develops into the intervertebral discs, and associated underlying molecular mechanisms, as well as intervertebral disc disease, such as IVD degeneration. The Research Services Principal Professional is expected to be the research lead for several ongoing projects, including design of experimental setup, data generation, and data interpretation, with the following key responsibilities:
- Perform molecular biology experiments and related animal work, including mouse husbandry, genotyping, tissue collection, see details below (~90% of work)
- Perform administrative tasks, see details below (~10% of work)
Key Responsibilities:
All Levels
- Collaborate with and support Principal Investigators (PI) and other stakeholders with laboratory and research functions
- Utilize a variety of laboratory techniques required for research projects
- Independently and creatively identify laboratory solutions
- Independently Review, develop and implement new or modified laboratory techniques required for research projects
- Assist Team Leads, Supervisors and/or management with creation and implementation of processes and procedures and quality improvement initiatives
- Assist and train junior team members.
Senior Level: All Duties listed above plus the following:
- Assist with developing or develop protocol-specific systems and documents including process flows, training manuals, and Standard Operating Procedures (SOPs). Maintains subject level documentation and prepares documents, equipment and/or supplies
- Assist with identifying issues related to operational efficiency and shares results with leadership
- Provide laboratory science expertise and leadership in study design, study oversight, data management, data analysis and manuscript preparation to assist all levels of investigators, researchers and clinicians on new research activities across a wide range of disciplines
- Serve as a resource to PIs and other stakeholders
Principal Level: All Duties listed above plus the following:
- Oversee and provide informal leadership to the team members including managing day-to-day priorities, evaluating and redistributing workloads on a temporary basis, and mentoring staff
- Provide input and feedback to leadership on team members overall performance, performance evaluations, opportunities for development, and process improvement initiatives
- Identify training and development opportunities for new and existing team members
- Act as a Subject Matter Expert and authority in the area(s) of zebrafish laboratory work and development of the spine.
Additional Duties & Responsibilities:
Wet lab key responsibilities:
- Conducting molecular biology experiments, such as, but not limited to: PCR, gateway cloning, restriction digest and T4 ligation, Sanger sequencing of plasmid vectors, RNA work, e.g. CRISPR guide RNA generation, mRNA generation, immunohistochemistry/fluorescence, Western blotting, RNA and genomic DNA collection from mouse for RNAseq and ATACseq experiments
- Work with different mouse mutant and transgenic strains, such as mouse husbandry/breeding, genotyping, dissection for tissue collection, e.g. spine, long bones, etc.
- Mouse skeletal and non-skeletal tissue harvest for histological analysis, including embedding, sectioning and imaging, and for RNA and genomic DNA preparation
Administrative responsibilities:
- Ordering consumables and materials, etc.
- Maintaining laboratory area and equipment in working and clean condition
- Contributing to animal protocol writing
- Handling EHS requirements
- Overseeing training from junior lab members
- Managing internal and external collaborations with key stakeholders
- Presentation of research findings, e.g. at department internal meetings, national and international scientific meetings
- Additional responsibilities related to position as assigned by PI
Work Location:
Onsite – this role is expected to work onsite and is located in Aurora, CO.
Why Join Us:
The University of Colorado, Department of Orthopedics is a recognized global leader in the field and Colorado's most trusted orthopedic group for adults and children. Our unique position at the forefront of medical science, education, and practice innovation translates in real-time to the most advanced patient care, unmatched in Colorado and the Rocky Mountain Region. From routine cases to the most complex, we treat every orthopedic condition including injuries and diseases of the bones, joints, nerves, tendons, ligaments, and muscles across many orthopedic specialties.
Why work for the University?
We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:
- Medical: Multiple plan options
- Dental: Multiple plan options
- Additional Insurance: Disability, Life, Vision
- Retirement 401(a) Plan: Employer contributes 10% of your gross pay
- Paid Time Off: Accruals over the year
- Vacation Days: 22/year (maximum accrual 352 hours)
- Sick Days: 15/year (unlimited maximum accrual)
- Holiday Days: 10/year
- Tuition Benefit: Employees have access to this benefit on all CU campuses
- ECO Pass: Reduced rate RTD Bus and light rail service
There are many additional perks & programs with the CU Advantage.
Minimum Qualifications:
Intermediate level:
- Bachelor’s degree in biology, molecular biology, chemistry, genetics or related field
- A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year for year basis
- One (1) year professional level wet lab research experience, including mouse work
Senior level:
- Bachelor’s degree in biology, molecular biology, chemistry, genetics or related field
- A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year for year basis
- Two (2) years professional level wet lab research experience, including mouse work
Principal level:
- Bachelor’s degree in biology, molecular biology, chemistry, genetics or related field
- A combination of education and related technical/paraprofessional experience may be substituted for the bachelor’s degree on a year for year basis
- Three (3) years professional level wet lab research experience, including mouse work
Preferred Qualifications
- Master’s degree in biology, molecular biology, chemistry, genetics or related field
- Four (4) years of experience in an experimental or wet laboratory, including mouse work
- Prior experience with molecular biology methods including, but not limited to PCR, cloning, immunoprecipitation, microscopy, RNA in situ hybridization
How to Apply:
For full consideration, please submit the following document(s):
- A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
- Curriculum vitae / Resume
- Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address
Questions should be directed to: Alexa Burger, ALEXA.BURGER@CUANSCHUTZ.EDU.
Screening of Applications Begins:
Screening begins immediately and continues until position is filled. For best consideration, apply by March 27, 2026.
Anticipated Pay Range:
The starting salary range (or hiring range) for this position has been established as HIRING RANGE
- Intermediate: $50,357-$64,054
- Senior: $54,440-$69,248
- Principal: $62,606-$79,635
The above salary range (or hiring range) represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level. Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line. Total Compensation Calculator
Equal Employment Opportunity Statement:
CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.
ADA Statement:
The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.
Background Check Statement:
The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.
Vaccination Statement:
CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.
University Staff Job Category
Research Services
Primary Location
Aurora
Department
U0001 -- Anschutz Med Campus or Denver
Schedule
Full-time
Posting Date
Feb 25, 2026
Unposting Date
Ongoing
Posting Contact Name
Thomas Roller
Posting Contact Email
thomas.roller@cuanschutz.edu
Position Number
00828755
See all 51+ Research at University of Colorado jobs
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Get Access To All JobsTips for Finding Research Jobs at University of Colorado Jobs
Align your credentials with NIH funding requirements
Many Research positions at CU are tied to federal grants from NIH or NSF, which specify degree and experience requirements in the award terms. Confirm your credentials explicitly match the funded project scope before applying, as mismatches can stall H-1B specialty occupation determinations.
Target principal investigators hiring on active grants
CU Research roles often originate with individual PIs managing funded projects, not central HR. Search the NIH Research Portfolio Online Reporting Tools to identify active CU awards in your field, then contact the PI directly before a formal posting appears.
Clarify sponsorship scope during your offer negotiation
CU's international office handles H-1B filings but timelines depend on department budget approval. Confirm during the offer stage whether your position qualifies for premium processing and whether the department covers USCIS filing fees, so there are no surprises after you accept.
Request an early PERM recruitment audit from your supervisor
If you're targeting a permanent Research role and eventual Green Card sponsorship via PERM, ask your supervisor to document the supervised recruitment process from day one. DOL requires demonstrated good-faith recruiting, and gaps in employer records are the most common cause of PERM delays.
Verify your OPT end date against CU's hiring timeline
CU's onboarding process for Research roles, including background checks and international office paperwork, can take four to six weeks after an offer is signed. If you're on F-1 OPT, count backward from your EAD expiration and flag any gap risk to the hiring department before the offer is finalized.
Browse open Research roles using Migrate Mate
Filter by visa type to surface CU Research positions that match your authorization status. Migrate Mate aggregates sponsoring employer listings so you can focus your applications on roles where the sponsorship pathway aligns with your timeline and visa category.
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Find Research at University of Colorado JobsFrequently Asked Questions
Does University of Colorado sponsor H-1B visas for Researchs?
Yes, University of Colorado sponsors H-1B visas for Research positions. CU's international offices across its campuses are experienced with the H-1B process for academic and research staff. Sponsorship is typically initiated after an offer is extended, and the university generally covers USCIS filing fees, though you should confirm premium processing coverage with your specific department during the offer stage.
How do I apply for Research jobs at University of Colorado?
Most Research positions are posted on CU's official jobs portal, but many funded roles are filled through direct outreach to principal investigators before they are formally advertised. Searching NIH and NSF grant databases for active CU awards in your field and contacting PIs directly is an effective strategy. You can also browse current openings filtered by visa sponsorship eligibility on Migrate Mate.
Which visa types does University of Colorado commonly use for Research roles?
CU sponsors H-1B, J-1, TN, and F-1 OPT and CPT for Research positions, with the pathway depending on your nationality, degree level, and role type. J-1 is common for postdoctoral researchers and visiting scholars. H-1B is standard for longer-term staff researcher positions. For Canadian and Mexican nationals in qualifying research roles, TN is a faster alternative. Permanent residency sponsorship through EB-2 or EB-3 is available for ongoing research staff.
What qualifications does University of Colorado expect for sponsored Research roles?
Requirements vary by role, but most sponsored Research positions require at least a master's degree in a relevant scientific or technical field, with a Ph.D. expected for principal or senior researcher titles. USCIS requires that H-1B specialty occupation positions have a direct relationship between the degree field and the job duties, so your academic background needs to match the specific research area, not just science broadly.
How long does the visa sponsorship process take for a CU Research position?
For H-1B sponsorship, standard USCIS processing takes three to six months after the petition is filed. Premium processing reduces that to 15 business days. CU's internal onboarding and international office review adds two to four weeks before the petition can be submitted. For J-1 researchers, DS-2019 issuance typically takes two to four weeks once the department initiates the request through CU's exchange visitor program.
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