Office Manager Jobs in South Carolina

Office Manager jobs in South Carolina are concentrated in Columbia, Charleston, and Greenville, where employers like Prisma Health, Boeing, and Michelin maintain large administrative operations across healthcare, aerospace, and manufacturing. Demand runs from entry-level office coordinator roles to senior office manager positions overseeing multi-site operations, with the strongest openings in medical practice management, corporate administration, and construction firm support. South Carolina's continued growth in advanced manufacturing and healthcare services keeps this role among the more active markets in the Southeast. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles69
Top employerState of South Carolina
Top cityGreenville, SC
Cities hiring31
Work type91% On-site
Top industryHealthcare

Showing 5 of 69+ Office Manager jobs

Cardiovascular Associates of America
Medical Office Site Manager
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Cardiovascular Associates of America
New 21h ago
Medical Office Site Manager
Cardiovascular Associates of America
Rock Hill, South Carolina
Business Operations
Project Management
Quality Assurance & Testing (QA Testing)
On-Site
Associate's degree in Business Administration
201-500

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Elite Home Care of South Carolina
Home Care Office Manager
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Elite Home Care of South Carolina
Added 1d ago
Home Care Office Manager
Elite Home Care of South Carolina
North Charleston, South Carolina
Business Operations
Customer Service
Project Management
501-1,000

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S
Office Manager
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S
Added 1d ago
Office Manager
SouthernMED
Charleston, South Carolina
Business Operations
Program Management
Project Management
High school diploma or GED

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Senior Living Communities
Business Office Manager - Senior Living
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Senior Living Communities
Added 1d ago
Business Office Manager - Senior Living
Senior Living Communities
Greenville, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Bachelor's degree
1,001-5,000

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Resurgent Capital Services, LP
Office Manager
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Resurgent Capital Services, LP
Added 2d ago
Office Manager
Resurgent Capital Services, LP
Greenville, South Carolina
Business Operations
501-1,000

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See All 69 Office Manager Jobs in South Carolina

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Office Manager Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Greenville
8 jobs
Charleston
7 jobs
Columbia
5 jobs
North Charleston
5 jobs
Sumter
3 jobs
Bluffton
3 jobs
Seneca
2 jobs
Anderson
2 jobs
Rock Hill
2 jobs

Office Manager Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

State of South Carolina
State of South Carolina8 open roles
The Aspen
The Aspen4 open roles
Greystar
Greystar3 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in office manager jobs across South Carolina.

  • Associate or bachelor's degree in business administration or a related field required
  • Three or more years of administrative or office management experience preferred
  • Proficiency in Microsoft Office Suite and cloud-based scheduling or project tools
  • Experience managing budgets, vendor relationships, and facilities coordination
  • Strong written and verbal communication skills for cross-departmental coordination
  • Familiarity with HIPAA compliance practices valued in healthcare office settings

Office Manager Jobs in South Carolina: Frequently Asked Questions

How do you become a office manager in South Carolina?

Office manager is not a state-licensed role in South Carolina, so there is no required exam or registration through a state board. Most employers expect at least an associate degree in business administration or a related field, though a bachelor's degree is increasingly preferred. Candidates who hold credentials like the Certified Administrative Professional designation or have completed business programs through South Carolina technical colleges tend to stand out in competitive applicant pools.

How much do office managers make in South Carolina?

Office managers in South Carolina earn a median of about $62,920 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $43,570 for the lowest 10% to over $99,680 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire office managers in South Carolina?

South Carolina office manager roles are posted by State of South Carolina, The Aspen, and Greystar and others right now, based on current listings on Migrate Mate as of September 2026. South Carolina's mix of large healthcare systems, aerospace manufacturers, and regional construction firms generates consistent office manager demand well beyond the major metros.

Which South Carolina cities have the most office manager jobs?

Greenville, Lexington County, and Charleston have the most office manager openings in South Carolina right now. Columbia leads because of its concentration of state government offices, university systems, and Prisma Health facilities, while Charleston and Greenville draw demand from aerospace, hospitality, and manufacturing employers that each require substantial administrative staff.

Are there remote office manager jobs in South Carolina?

Yes, but they're relatively limited. About 9% of office manager openings tied to South Carolina are remote or hybrid as of September 2026, reflecting that most office manager roles involve on-site coordination of staff, vendors, and facilities. The tasks most commonly performed remotely include scheduling, reporting, and communications work for employers with distributed or hybrid teams.

How can I get hired as a office manager in South Carolina with little or no experience?

The most realistic entry path is through an administrative assistant or office coordinator role at a South Carolina healthcare system or corporate employer, then moving into management once you have direct supervisory experience. Prisma Health and MUSC both hire entry-level administrative staff into positions that build toward office management. Completing a business administration program at a South Carolina technical college and earning the Certified Administrative Professional credential gives candidates with limited experience a concrete edge in the hiring process.

Where can I find and apply to office manager jobs in South Carolina?

You can find and apply to office manager jobs in South Carolina on Migrate Mate, which lists current openings from employers actively hiring across the state. Search the listings, find the roles that match your experience and location, and apply directly to the ones that fit.

See All 69 Office Manager Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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