Enterprise Sales Director Jobs in Missouri
Enterprise Sales Director jobs in Missouri concentrate heavily in financial services, healthcare technology, logistics, and B2B software, with the state's central location making it a natural hub for regional and national account management roles. St. Louis, Kansas City, and Springfield anchor most of the hiring, where employers like World Wide Technology, Cerner (now Oracle Health), and Edward Jones maintain large enterprise sales operations. The most consistent demand is for directors with experience closing complex SaaS deals, managed services contracts, or healthcare IT solutions. Scan the live roles below and apply to whichever ones fit.
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RGA is a purpose-driven organization working to solve today’s challenges through innovation and collaboration. A Fortune 200 Company and listed among its World’s Most Admired Companies, we’re the only global reinsurance company to focus primarily on life- and health-related solutions. Join our multinational team of intelligent, motivated, and collaborative people, and help us make financial protection accessible to all.
A Brief Overview
The Executive Director, Enterprise Regional Enablement, serves as the single accountable leader for operational risk enablement within assigned regions. The role holder translates enterprise frameworks, methodologies, and Centers of Excellence (CoE) assets for regional use, adapting to local regulatory regimes, business lines, and operating maturity. This includes building regional risk practitioner capability, ensuring enterprise standards are implemented consistently, and serving as the primary enablement interface between enterprise and regional stakeholders.
What you will do
- Serve as the named operational risk enablement partner for regional business unit heads — maintaining a regular engagement cadence with each major regional business unit to understand needs, track progress, and resolve barriers — and build and maintain productive relationships with regional business leaders, local compliance teams, Internal Audit, and other key stakeholders across the first, second, and third lines of defense.
- Translate the enterprise framework, methodologies, Key Risk Indicator (KRI) standards, taxonomies, and reporting templates for regional use — incorporating local regulatory overlays, language, currency, and business-line specifics without altering the underlying enterprise standard — and coordinate with specialty CoEs so regional businesses can access their services, contextualizing specialty playbooks for the regional operating environment as needed.
- Deploy the regional team (analysts, leads) as embedded advisors to regional business units executing Risk and Control Assessments (RCAs), KRI design, incident write-ups, scenario analysis, and remediation planning. Coach first-line practitioners to execute risk activities independently.
- Lead the regional control program — implement enterprise control standards and control-assessment methodologies consistently across the assigned regions, accounting for local regulatory overlays without altering the underlying enterprise standard. Oversee first-line business unit regional control monitoring, control testing, and control-effectiveness evaluation; track control gaps and remediation in-region; and partner with regional Internal Audit (3rd line) and local compliance teams on integrated control assurance, supporting alignment of regional RCA outputs and control-testing results with the enterprise control framework, assurance program, and reporting.
- Coordinate with regional risk leaders on training calendars, risk practitioner communities of practice, and regional roundtables. Champion operational risk culture change in the region and support enterprise change management initiatives at the regional level. Feed regional learning needs back to the ED, Enterprise Ops Risk Enablement Strategy, Framework & Reporting.
- Monitor regional regulatory developments and serve as the first point of contact when regional businesses identify significant incidents or emerging risks — briefing the VP, Head of Enterprise Operational Risk Enablement and relevant CoEs on emerging requirements, building relationships with regional regulatory-facing teams so Enablement is engaged early, and triaging and routing issues to the appropriate CoE or Oversight function so enterprise visibility is established promptly.
- Ensure regional risk data flows into enterprise reporting processes. Quality-control regional submissions before integration into enterprise datasets. Contribute regional risk insights, themes, and data to support briefing papers for the Board Risk Committee, Risk Management Steering Committee, and Operational Risk Committee.
- Support regional execution of risk exposure quantification methodologies, as appropriate, including scenario analysis and loss modeling, in coordination with the enterprise Risk Quantification CoE.
- Represent regional user needs in GRC platform decisions. Partner with the ED, Enterprise Ops Risk Enablement Strategy, Framework & Reporting to drive adoption and effective use of enterprise tooling in the region.
- Build and develop a high-performing regional team. Manage analysts and leads in-region, including talent development, succession planning, and performance management.
Qualifications
- Bachelor’s Degree in Arts/Sciences (BA/BS) in Risk Management, Finance, Business, Economics, or related field, or equivalent experience required
- 10+ Years of progressive experience in operational risk management, enterprise risk, internal audit, internal controls, or a related second-line risk function within financial services or insurance, including demonstrated experience designing or maintaining a risk management framework required
- 5+ Years of people management experience, including building or leading teams in a regional or matrixed environment required
- 5+ Years of experience in the insurance or reinsurance industry required
- 3+ Years of experience working across multiple geographies, regulatory regimes, or cultural contexts. Proven proficiency in AI, spreadsheets, and databases required
- Experience working with an Enterprise Integrated Risk Management / GRC platform (e.g., ServiceNow IRM, Archer, MetricStream) required
- 12+ Years of operational risk management experience including framework design and engagement with senior executives, regulators, and the Board preferred
- Experience designing risk quantification approaches covering inherent/residual risk and control effectiveness preferred
- Experience driving adoption of new risk management practices, tools, or frameworks, with a coaching-oriented approach to capability building and applied knowledge of effective change management principles required
- Proven proficiency in AI, spreadsheets, and databases required
- Deep working knowledge of operational risk management frameworks, methodologies (RCA, KRI, scenario analysis, loss event capture), and related regulatory expectations (NAIC ORSA, Solvency II, COSO, ISO 31000). required
- Proficient with GRC platforms (e.g., Archer, ServiceNow IRM, MetricStream), reporting and visualization tools (e.g., Power BI), and emerging AI tools applied to risk reporting and analytics. required
- Demonstrated ability to lead, influence, and build trust across diverse cultural, regulatory, and linguistic contexts, including experience managing geographically dispersed virtual teams. required
- Ability to translate enterprise-level strategy into regional execution plans that account for local constraints and opportunities required
- Professional risk management certification (e.g., FRM, PRM, ORM, CRMA). Lean / Six Sigma or Change Management certification preferred
#LI-MJ1 #LI-REMOTE
What you can expect from RGA:
Gain valuable knowledge from and experience with diverse, caring colleagues around the world.
Enjoy a respectful, welcoming environment that fosters individuality and encourages pioneering thought.
Join the bright and creative minds of RGA, and experience vast, endless career potential.
We’re excited to get to know you and connect your unique skills with our global opportunities. To create a modern and seamless experience, we use artificial intelligence (AI) in parts of our preliminary screening process. This technology helps us personalize job recommendations, automate interview scheduling, evaluate candidates based solely on experience—without considering name, gender, or other personal details—and provide real-time answers through our chatbot. AI is used only during early screening and never makes hiring decisions. Your RGA recruiter will work closely with you every step of the way to ensure the process feels personal, thoughtful, and focused on you.
Compensation Range:
$126,710.00 - $188,840.00 AnnualBase pay varies depending on job-related knowledge, skills, experience and market location. In addition, RGA provides an annual bonus plan that includes all roles and some positions are eligible for participation in our long-term equity incentive plan. RGA also maintains a full range of health, retirement, and other employee benefits.
RGA is an equal opportunity employer. Qualified applicants will be considered without regard to race, color, age, gender identity or expression, sex, disability, veteran status, religion, national origin, or any other characteristic protected by applicable equal employment opportunity laws.
See All 9 Enterprise Sales Director Jobs in Missouri
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Find JobsEnterprise Sales Director Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Enterprise Sales Director Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring



What Missouri Employers Look For
The qualifications that appear most often in enterprise sales director jobs across Missouri.
- Bachelor's degree in business, marketing, or a related field required by most Missouri employers
- Seven or more years of B2B sales experience with a demonstrated history of closing enterprise contracts
- Proven ability to manage and grow a quota-carrying team across multiple Missouri territories
- Experience selling into one of Missouri's core verticals: healthcare, financial services, or logistics
- Strong CRM proficiency, typically Salesforce, for pipeline management and forecasting
- Ability to travel regularly within Missouri and to key accounts in surrounding Midwest markets
Enterprise Sales Director Jobs in Missouri: Frequently Asked Questions
How do you become an enterprise sales director in Missouri?
Most enterprise sales directors in Missouri follow a path that starts with a bachelor's degree in business, marketing, or a technical field, then progresses through individual contributor and sales management roles before reaching director level. Missouri does not require a state-issued license for this role. Employers in St. Louis and Kansas City typically expect candidates to have managed large quota-carrying teams, with experience in a sector like healthcare IT, financial services, or supply chain technology giving a strong competitive edge.
How much do enterprise sales directors make in Missouri?
Enterprise sales directors in Missouri earn a median of about $115,370 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $60,920 for the lowest 10% to over $223,340 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire enterprise sales directors in Missouri?
Companies currently hiring enterprise sales directors in Missouri include RGA, Mercy, and CK Power, per current listings on Migrate Mate as of November 2026. Missouri's concentration of healthcare technology, financial services, and logistics firms means demand is consistent across both large enterprises and regional players headquartered in the St. Louis and Kansas City corridors.
Which Missouri cities have the most enterprise sales director jobs?
St. Louis, Chesterfield, and Parkville account for the largest share of enterprise sales director openings in Missouri. St. Louis drives volume through its dense cluster of healthcare, financial services, and technology employers, while Kansas City's strength in logistics, telecommunications, and B2B software supports steady hiring, and smaller markets reflect anchor employers or regional divisional offices that generate openings independently of the major metros.
Are there remote enterprise sales director jobs in Missouri?
Yes, and more than most fields, since enterprise sales work is relationship-driven and often conducted remotely with clients. About 50% of enterprise sales director openings tied to Missouri are remote or hybrid as of November 2026, reflecting how well the role adapts to distributed teams. Strategic planning, pipeline management, and client presentations are the functions most commonly handled remotely, while new business development and executive stakeholder meetings still tend to require in-person presence.
How can I get hired as an enterprise sales director in Missouri with little or no experience?
The most realistic path is moving up from a senior account executive or regional sales manager role at a Missouri employer, rather than applying directly to director-level postings. Large St. Louis and Kansas City employers in healthcare technology and financial services, including companies like World Wide Technology and regional insurance carriers, regularly promote from within and post associate director or sales team lead roles as stepping stones. Building a record of quota attainment, earning a Salesforce certification, and pursuing a formal management role in your current organization are the moves that open the door fastest.
Where can I find and apply to enterprise sales director jobs in Missouri?
You can find and apply to enterprise sales director jobs in Missouri on Migrate Mate, which lists current Missouri openings updated in real time. Search the listings, find the roles that match your background and target sector, and apply directly to the ones that fit.
See All 9 Enterprise Sales Director Jobs in Missouri
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