Enterprise Sales Director Jobs in Missouri
Enterprise Sales Director jobs in Missouri are open across Pacific, St. Louis, and Kansas City and other Missouri metros, with employers like Parallel Wireless, Block, and Incyte Corporation hiring at every experience level. Find a role that fits below and apply directly.
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Overview:
A global biopharmaceutical company on a mission to Solve On, Incyte follows science to find solutions for patients with unmet medical needs. Through the discovery, development, and commercialization of proprietary therapeutics, Incyte has established a portfolio of first-in-class medicines for patients and a strong pipeline of products in Hematology, Oncology and Inflammation and Autoimmunity.
Headquartered in Wilmington, Delaware, Incyte has operations in North America, Europe, and Asia.
We are looking for a dynamic and strategic Sales Leader to lead our Immunology/Dermatology field sales team focused on launching a first-in-class product for Hidradenitis Suppurativa (HS). The Immunology Business Director (IBD) will be accountable for translating brand strategy into disciplined field execution, coaching and developing high-performing Therapeutic Specialists, and delivering demand generation to support launch excellence and sustained growth. The ideal candidate brings deep experience in specialty markets, a passion for patient-centric, clinical selling, and a proven ability to lead in a cross-functional, fast-paced environment. This is an opportunity to lead a purpose-driven team in delivering impactful therapies to underserved patient populations. This leader will foster a high-performance, compliant, and patient-centric culture grounded in a deep understanding of the HS patient journey and unmet needs to optimize patient access, outcomes, and overall customer experience.
ESSENTIAL FUNCTIONS & KEY RESPONSIBILITIES:
Leadership & Talent Development:
- Lead, coach, and develop a team of Immunology Therapeutic Specialists.
- Build a culture of high performance, accountability, integrity, and compliance.
- Lead and execute regional business plans to achieve sales and performance objectives for the HS portfolio.
- Translate national strategy into clear priorities, effective call execution, strong account planning, and local market action plans.
- Provide consistent field coaching through ride-alongs/joint calls, observation, and skill-building.
- Identify, develop, and retain top talent and future leaders.
Sales Strategy & Launch Execution:
- Collaborate with commercial leadership to execute regional launch strategies for a new HS therapy.
- Deliver against aggressive launch and growth targets from pre-launch through maturity.
- Analyze regional performance data to identify opportunities, optimize resources, and drive results.
Market Access, Pull-Through & Fulfillment:
- Demonstrate strong understanding of payer, reimbursement, and access dynamics, including formularies, step edits, and prior authorizations.
- Lead teams in navigating complex access and fulfillment processes in partnership with internal Market & Patient Access matrix partners.
- Support customer offices to overcome access barriers, understand benefits verification, prior authorization, bridge programs, copay assistance, and specialty pharmacy distribution.
- Provide field insights and escalate recurring access/fulfillment barriers through established channels to improve the patient experience compliantly.
- Experience with HUB services and patient support programs required.
Key Account Customer Engagement & Market Development:
- Build and maintain strong relationships with key dermatology stakeholders and opinion leaders.
- Implement institutional and local market strategies to drive launch adoption.
- Ensure delivery of compelling, compliant, and data-driven clinical and value messages across diverse customer audiences.
- Coach the team to build strong relationships with HS-treating customers and key accounts (e.g., high-volume dermatology practices, “super-groups,” and institutional systems where applicable).
Cross-Functional Collaboration:
- Partner with Market Access, Medical Affairs, Marketing, and Operations to ensure alignment and execution excellence.
- Provide actionable field insights to inform strategy, messaging, local market action planning, and tactical refinement.
Compliance & Integrity:
- Ensure all activities adhere to regulatory, legal, and company compliance standards.
- Model ethical leadership and reinforce compliance expectations across the team.
Continuous Learning & Adaptation:
- Stay current on evolving HS science, competitive landscape, and market dynamics.
- Foster learning agility, adaptability, and continuous improvement within the team.
- Thrive in high-pressure, ambiguous launch environments.
- Demonstrate persistence in overcoming access & prescribing barriers.
QUALIFICATIONS
Required
- Bachelor’s degree or equivalent relevant experience required.
- Experience in competitive specialty markets and/or systemic, injectable biologics, or oral JAK with a strong track record of results.
- Demonstrated people-leadership experience coaching and developing sales talent (first-line leadership preferred).
- Cross-functional experience partnering with Marketing, Market Access, and/or Operations.
- Ability to lead in a fast-paced, cross-functional environment with strong business acumen and execution discipline.
- Proficiency in Microsoft Office and CRM/database applications.
- Ability to travel within the region as required.
- Valid driver’s license and acceptable driving record.
Preferred
- Dermatology and/or immunology experience; HS experience strongly preferred.
- Strong experience with institutional, super group, and key account dynamics.
- Experience supporting a launch and driving sustained growth post-launch.
The successful candidate may be hired at a level commensurate with their experience, skills, qualifications, and capabilities. The final job level and compensation package will be determined based on an assessment of the candidate's qualifications and alignment with the requirements of the role, within the applicable salary range.
DISCLAIMER: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.
Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.
We Respect Your Privacy
The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate.
During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job.
You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work.
Pay Range: USD $230,000.00 - USD $293,700.00 /Yr.
See All 7 Enterprise Sales Director Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find JobsEnterprise Sales Director Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Enterprise Sales Director Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
- Parallel Wireless3

- Block1

- Incyte Corporation1

- Jumpcloud1

- Stella-Jones1

Top Industries Hiring
- Technology & Software3
- Biotechnology & Pharmaceuticals1
- Consulting & Professional Services1
- Cybersecurity1
- Telecommunications1
What Missouri Employers Look For
The qualifications that appear most often in enterprise sales director jobs across Missouri.
- 7 or more years of enterprise B2B sales experience with consistent quota attainment
- Proven ability to manage and grow a high-performing sales team
- Experience closing complex, multi-stakeholder deals with long sales cycles
- Proficiency with CRM platforms such as Salesforce or Microsoft Dynamics
- Strong command of sales forecasting, pipeline management, and revenue reporting
- Bachelor's degree in business, technology, or a related field
Enterprise Sales Director Jobs in Missouri: Frequently Asked Questions
How many enterprise sales director jobs are there in Missouri?
There are 7+ enterprise sales director openings in Missouri on Migrate Mate as of June 2026, with the most roles in Pacific, St. Louis, and Kansas City. New positions post regularly as employers across Missouri hire.
How much do enterprise sales directors make in Missouri?
Enterprise sales directors in Missouri earn a median of about $115,370 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $60,920 for the lowest 10% to over $223,340 for the top 10%. Pay rises with experience, specialty, and employer.
Which Missouri cities have the most enterprise sales director jobs?
Pacific, St. Louis, and Kansas City have the most enterprise sales director openings in Missouri right now, with additional roles spread across smaller metros statewide.
Which companies hire enterprise sales directors in Missouri?
Employers hiring enterprise sales directors in Missouri include Parallel Wireless, Block, and Incyte Corporation, based on current listings on Migrate Mate as of June 2026.
Are there remote enterprise sales director jobs in Missouri?
Yes. About 29% of enterprise sales director openings tied to Missouri are remote or hybrid as of June 2026. The rest are on-site roles based in Missouri metros.
How do I apply for enterprise sales director jobs in Missouri?
You can apply to enterprise sales director jobs in Missouri directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Missouri location, then apply to each one that fits.
See All 7 Enterprise Sales Director Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
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