Enterprise Sales Executive Jobs in South Carolina
Enterprise Sales Executive jobs in South Carolina are concentrated in Columbia, Charlotte-adjacent markets like Rock Hill, and the Greenville-Spartanburg corridor, where technology, manufacturing, and financial services companies maintain significant operations. Employers with a lasting presence in the state include Michelin, Blackbaud, and Synnex, all of which hire enterprise sales professionals to manage complex B2B accounts. The most in-demand specialties are SaaS and software solutions, industrial and manufacturing sales, and financial technology. See the openings below and apply to the ones that match your experience.
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At Commure, we're building the AI Operating System for healthcare, the foundation that defines how care is delivered, documented, and financed. Our platform spans the full care journey: Ambient AI and Dictation eliminating documentation burden at the point of care, intelligent Agents automating patient and revenue workflows, and autonomous RCM processing billions in claims, all on a single AI-native platform integrated with 60+ EHRs. Healthcare carries a $1 trillion administrative burden and we're at the center of transforming it. Today, 500,000+ clinicians across 500+ healthcare organizations nationwide trust Commure to handle $25B+ in annual claims and support over 200 million patient interactions. Our latest $70M raise at a $7B valuation reflects the confidence the market has placed in this mission. We've also been named to the Fortune Future 50 list and the 2026 AI Breakthrough Awards for “Overall NLP Company of the Year.” Our team works directly alongside clinicians, not through layers of process, which means the gap between what you build and its impact on patient care is immediate. We move fast, deploy daily, and take full ownership from early thinking to production. If you're energized by hard problems, high stakes, and a team that holds itself to a high bar, you'll find your people here. The future of healthcare is being built right now. Come deliver this transformation.
About The Role
Join Commure as an Enterprise Account Executive and take ownership of a growing territory in Texas as we expand into new enterprise visibility solutions. You'll drive some of our largest and most strategic revenue growth opportunities. We're seeking passionate relationship builders and deal-makers to accelerate our mission. Reporting to the VP of Sales within the enterprise team, you'll be a key player in our enterprise growth.
- Strategic Sales Management: Own the full sales cycle, from lead generation through contract negotiation, engaging internal and external resources to maximize results.
- Revenue Achievement: Consistently meet and exceed quarterly and annual revenue targets.
- Relationship Cultivation: Build and maintain strong relationships with prospective clients at all stages of the sales process.
- Consultative Solution Selling: Deliver tailored, consultative solutions that address client needs and drive business outcomes.
- Sales Operations: Accurately track customer contact information, deal management, and forecast sales.
- High-Value Deal Closure: Drive and close large deals ($1M+), while also identifying and capitalizing on land-and-expand opportunities within our growing enterprise visibility platform.
- Exceed Quota: Proactively generate new business through your existing relationships, self-driven initiatives, inbound lead management, industry events, and strategic renewals and upsells.
- Contract Negotiation: Develop winning strategies, build key stakeholder relationships, scope solution requirements, and negotiate deals through contract signing.
- Client Performance Management: Drive revenue growth within existing accounts and expand into new enterprise solutions by delivering against client performance metrics.
- Pipeline Development: Identify, prioritize, and qualify key buying influences, and effectively guide them through the sales process.
- Industry Expertise: Cultivate relationships with customers, decision-makers, and thought leaders, and stay abreast of new product developments and their potential market impact.
What You Have
- Extensive Healthcare Sales Experience: 8+ years of experience selling into large healthcare systems, engaging with C-level executives (CNOs, CIOs, CTOs) and high-level operational leaders (VPs, Directors).
- Sales Cycle Expert: Proven expertise in building pipelines, moving opportunities through complex sales cycles, and effectively presenting and discussing solutions with key decision-makers. You know how to "drive a deal.”
- Passionate Evangelist: A highly energetic and driven individual with a strong sense of urgency and a deep belief in our mission.
- Collaborative Team Player: Understanding of early-stage company dynamics and the importance of teamwork. You thrive in fast-paced, resource-constrained environments and embrace the "build-it-yourself" ethos.
- Proven Track Record: Consistently achieved and exceeded revenue targets and sales goals.
- SFDC Proficiency: Expert-level experience using Salesforce for forecasting, opportunity management, and reporting.
- Consultative Sales Approach: Exceptional consultative sales skills, including the ability to define customer needs, qualify opportunities, present tailored solutions, and articulate business outcomes.
Please be aware that all official communication from us will come exclusively from email addresses ending in @commure.com. Any emails from other domains are not affiliated with our organization. Employees will act in accordance with the organization’s information security policies, to include but not limited to protecting assets from unauthorized access, disclosure, modification, destruction or interference nor execute particular security processes or activities. Employees will report to the information security office any confirmed or potential events or other risks to the organization. Employees will be required to attest to these requirements upon hire and on an annual basis.
Compensation Range: $118K - $140K
See All 6 Enterprise Sales Executive Jobs in South Carolina
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Find JobsEnterprise Sales Executive Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Enterprise Sales Executive Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Technology & Software
- Non-Profit & Social Services
- Consulting & Professional Services
What South Carolina Employers Look For
The qualifications that appear most often in enterprise sales executive jobs across South Carolina.
- Five or more years of B2B enterprise sales experience with a consistent record of closing large accounts
- Bachelor's degree in business, marketing, technology, or a related field
- Demonstrated ability to manage full sales cycles from prospecting through contract negotiation
- Experience selling to C-suite and senior decision-makers across multiple business units
- Proficiency with CRM platforms such as Salesforce to manage pipelines and forecast revenue
- Strong presentation and communication skills suited to complex, multi-stakeholder deals
Enterprise Sales Executive Jobs in South Carolina: Frequently Asked Questions
How do you become an enterprise sales executive in South Carolina?
Enterprise sales executive roles in South Carolina do not require a state-issued license or exam. Most employers expect a bachelor's degree in business, marketing, or a technical field, combined with several years of progressively senior B2B sales experience. In South Carolina, the most direct path runs through industries like advanced manufacturing, technology services, and financial services, where companies in Greenville, Columbia, and the Charleston area regularly recruit candidates who have managed large accounts.
How much do enterprise sales executives make in South Carolina?
Enterprise sales executives in South Carolina earn a median of about $77,130 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $47,630 for the lowest 10% to over $141,210 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire enterprise sales executives in South Carolina?
Companies currently hiring enterprise sales executives in South Carolina include Yodeck, Commure, and Gordian, per current listings on Migrate Mate as of September 2026. South Carolina's concentration of global manufacturers, software companies, and financial services firms means enterprise sales demand is spread across both the Upstate and the Midlands regions.
Which South Carolina cities have the most enterprise sales executive jobs?
South Carolina, Columbia, and Charleston have the most enterprise sales executive openings in South Carolina. Columbia anchors demand as the state capital and home to major financial and technology employers, while Greenville and Spartanburg draw openings from the Upstate's dense cluster of advanced manufacturing, logistics, and international corporations that maintain regional headquarters or large operations there.
Are there remote enterprise sales executive jobs in South Carolina?
Yes, and more than most fields. About 50% of enterprise sales executive openings tied to South Carolina are remote or hybrid as of September 2026, reflecting how much of this work involves phone, video, and digital communication with distributed clients. The portions of the role most likely to stay fully remote are pipeline management, executive presentations, and account strategy, while high-value prospect visits and contract closings often require in-person travel.
How can I get hired as an enterprise sales executive in South Carolina with little or no experience?
The most realistic entry path is through an inside sales or account executive role at a South Carolina technology or manufacturing company, then moving up once you have a record of closed deals. Large Upstate employers in advanced manufacturing and SaaS regularly hire sales development representatives as a feeder path. Building familiarity with Salesforce and earning a recognized sales methodology certification, such as Challenger or MEDDIC, gives candidates without enterprise experience a concrete edge in South Carolina interviews.
Where can I find and apply to enterprise sales executive jobs in South Carolina?
You can find and apply to enterprise sales executive jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the roles that fit your background and apply directly to the ones that match your experience and target industry.
See All 6 Enterprise Sales Executive Jobs in South Carolina
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