Operations Manager Jobs in Missouri
Operations Manager jobs in Missouri concentrate in Kansas City, St. Louis, and Springfield, where manufacturers, distributors, and healthcare systems maintain large operational footprints. Companies like Cerner (now Oracle Health), Emerson Electric, and Anheuser-Busch InBev drive consistent demand across supply chain, logistics, and process improvement specialties. The market attracts candidates from entry-level supervisors stepping into their first management seat through senior directors overseeing multi-site operations. See the openings below and apply to the ones that match your experience.
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Job Summary
This role will manage the daily donor center operations.
This is What You’ll Do
- Maintain compliance with all federal, state, and local regulations (e.g., FDA approved SOPs, OSHA, CLIA, GMP) to ensure the highest production, safety, and quality standards.
- Assist with internal and external inspections, audits, and collaborate with departments to implement corrective and preventive actions (CAPA).
- Participate in quality improvement initiatives to enhance efficiency, optimize processes, and contribute to best practices.
- Promote and enforce Safety, Health, and Environmental policies; conduct safety training, mitigate unsafe conditions, and ensure a safe work environment.
- Oversee preventive maintenance of donor center equipment, ensuring operational readiness and facility cleanliness.
- Safeguard the integrity of product and sample storage equipment; prepare product shipments, manage unsuitable products, and mitigate equipment failures per SOPs.
- Support operational and fiscal goals by assisting with production targets, cost optimization, and inventory management.
- Provide input on employee performance management, including evaluations, improvement plans, and corrective actions, and support employment decisions such as hiring, promotions, and terminations.
- Foster a positive, inclusive culture within the center while ensuring adherence to HR policies, procedures, and employee relations practices.
- Act as a Designated Trainer, conducting on-the-job and certification training, assessing progress, and adapting teaching methods to regulatory and learner needs.
- Maintain visible leadership through area walkthroughs, provide assistance to ensure productivity and operational effectiveness.
- Cultivate positive donor relationships to encourage retention, referrals, and growth, while resolving complaints and supporting marketing initiatives.
- Manage scheduling, payroll records, and staff meetings to ensure efficient allocation of resources and productivity.
- Monitor and drive operational performance to Key Performance Indicators (KPIs), proactively addressing deficiencies and collaborating with leadership as needed.
- Perform other related duties as assigned.
This is What it Takes
Minimum Requirements
- High School Diploma, or equivalent (GED) with 12 months applicable experience.
- 1 year of operations and/or process management/supervisory experience preferred.
- 1 year of people management preferred including recruiting, training, etc.
- Trained in all production areas.
Required Certifications, Licenses, and Registrations
- N/A
Knowledge, Skills, and Abilities
- Ability to function effectively in a fast-paced environment with frequent interruptions.
- Excellent written, verbal, organizational, and interpersonal communication skills.
- Ability to work in a highly regulated industry is preferred.
- Proficiency with office software is preferred.
Physical Requirements
- Ability to sit or stand for extended periods of time.
- Ability to tug, lift, and pull up to thirty-five (35) pounds.
- Ability to bend, stoop or kneel as necessary.
- Ability to enter an environment with a temperature of -40°C for short periods of time.
- Occupational exposure to blood borne pathogens.
- Ability to view video display terminal less than 18” away from face for extended periods of time.
- Ability to perform precise tasks that require repetitive small motor skills, such as drawing blood for diagnostic tests.
- Ability to use a computer and other office equipment.
- Ability to use assistive devices if needed for mobility or communication.
- Ability to work daytime and evening hours, weekends, holidays, extended shifts and periodically after hours.
- Ability to travel up to 20% via airplane and vehicle (if applicable).
- Ability to focus and concentrate on tasks for extended periods.
- Ability to navigate the office environment safely, including stairs and elevators (if applicable).
Do Satisfying Work. Earn Real Rewards and Benefits
We’re widely known and respected for our benefits and for leadership that is supportive and hands-on. Managers who truly want you to grow and excel.
- Formal training
- Outstanding plans for medical, dental, and vision insurance
- Health savings account (HSA)
- Flexible spending account (FSA)
- Tuition Reimbursement
- Employee assistance program (EAP)
- Wellness program
- 401k retirement plan
- Paid time off
- Company paid holidays
- Personal time
Pay Transparency
With donation centers and team members throughout the U.S., Octapharma Plasma, Inc. collects plasma to create life-saving medicines for patients worldwide. We are growing at an impressive pace, and so is the positive impact of our work. Our community relies on teamwork, compassion, and expertise to get things done the right way, while making a meaningful difference in the lives we touch.
Interested? Learn more online and apply now at:
octapharmaplasma.com
And if you know someone else who'd be a great fit at Octapharma Plasma, Inc. please forward this posting along!
INNER SATISFACTION.
OUTSTANDING IMPACT.
See All 221+ Operations Manager Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find Operations Manager JobsOperations Manager Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Operations Manager Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Sports & Recreation
- Energy
- Retail
- Automotive
- Hospitality & Tourism
What Missouri Employers Look For
The qualifications that appear most often in operations manager jobs across Missouri.
- Bachelor's degree in business administration, supply chain, or a related field required
- Three or more years of direct team leadership or supervisory experience in operations
- Demonstrated proficiency with ERP systems such as SAP, Oracle, or Microsoft Dynamics
- Lean, Six Sigma, or continuous improvement certification strongly preferred by Missouri employers
- Ability to manage P&L responsibilities, budgets, and cost-reduction initiatives independently
- Strong written and verbal communication skills for cross-functional coordination and reporting
Operations Manager Jobs in Missouri: Frequently Asked Questions
How do you become a operations manager in Missouri?
Missouri does not require a state-issued license or registration to work as an operations manager, so the path runs through education and verified experience. Most Missouri employers expect at least a bachelor's degree in business, operations management, or a related discipline. Candidates who earn a Lean Six Sigma Green Belt or Project Management Professional credential are consistently prioritized in competitive markets like Kansas City and St. Louis, where manufacturing and logistics employers use those credentials as a practical filter.
How much do operations managers make in Missouri?
Operations managers in Missouri earn a median of about $79,300 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $42,460 for the lowest 10% to over $188,820 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire operations managers in Missouri?
Companies currently hiring operations managers in Missouri include Walgreens, Amazon, and CVS Health, per current listings on Migrate Mate as of November 2026. Missouri's mix of Fortune 500 headquarters, regional distribution centers, and large healthcare networks means demand is spread across industries rather than concentrated in a single sector.
Which Missouri cities have the most operations manager jobs?
St. Louis, Kansas City, and Springfield account for the largest share of operations manager openings in Missouri. Kansas City's role as a major freight and logistics hub anchors demand there, while St. Louis draws openings from its headquarters-heavy corporate base and healthcare systems, and Springfield's manufacturing and retail distribution networks support steady hiring in the southwest corridor.
Are there remote operations manager jobs in Missouri?
Yes, but they're rare. Operations management is largely a hands-on, on-site role tied to physical facilities, teams, and production lines, so fully remote positions are uncommon. About 30% of operations manager openings tied to Missouri are remote or hybrid as of November 2026, and those tend to be in process oversight, vendor coordination, or multi-site program management functions that don't require a daily physical presence.
How can I get hired as a operations manager in Missouri with little or no experience?
The most realistic entry path is moving up from a team lead or shift supervisor role within a Missouri manufacturing plant, distribution center, or healthcare facility. Large employers like distribution operations tied to Kansas City's logistics corridor and hospital networks in St. Louis regularly promote from within, and pursuing an associate operations manager or operations coordinator title first gives candidates the documentation of leadership they need. Earning a Lean Six Sigma White or Yellow Belt while in those roles signals initiative and helps candidates compete for the next step.
Where can I find and apply to operations manager jobs in Missouri?
You can find and apply to operations manager jobs in Missouri on Migrate Mate, which lists current openings across the state. Search the roles above, identify positions that match your background and preferred location, and apply directly to the ones that fit.
See All 221+ Operations Manager Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
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