Regional Manager Jobs in South Carolina

Regional Manager jobs in South Carolina are most active in Columbia, Charleston, and Greenville, where employers across retail, logistics, healthcare, and manufacturing maintain multi-unit or multi-site operations that require experienced regional leadership. Companies such as Michelin, Prisma Health, and Walmart have established large footprints in the state and consistently hire regional managers to oversee distributed teams and drive operational performance. Demand is strongest in operations management, retail and consumer goods, and healthcare services administration. See the openings below and apply to the ones that match your experience.

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Overview

Open roles51
Top employerState of South Carolina
Top cityLexington County, SC
Cities hiring20
Work type50% Hybrid
Top industryRetail

Showing 5 of 51+ Regional Manager jobs

LCG Freight Inc
Regional Account Manager – Intermodal (House Accounts)
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LCG Freight Inc
New 17h ago
Regional Account Manager – Intermodal (House Accounts)
LCG Freight Inc
Summerville, South Carolina
Logistics & Fleet Management
Procurement & Supply Chain
Supply Chain
$48k - $55k/yr
On-Site
11-50

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State of South Carolina
Regional Finance Manager / Accounting - Fiscal Manager III (Pee Dee Region)
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State of South Carolina
New 19h ago
Regional Finance Manager / Accounting - Fiscal Manager III (Pee Dee Region)
State of South Carolina
Lexington County, SC
Business Operations
Program Management
Project Management
$110k - $130k/yr
Hybrid
Bachelor's degree in finance
10,000+

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State of South Carolina
Regional Finance Manager / Accounting - Fiscal Manager III (Upstate Region)
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State of South Carolina
New 19h ago
Regional Finance Manager / Accounting - Fiscal Manager III (Upstate Region)
State of South Carolina
Lexington County, SC
Business Operations
Program Management
Project Management
$110k - $130k/yr
Hybrid
Bachelor's degree in finance
10,000+

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State of South Carolina
Regional Finance Manager / Accounting - Fiscal Manager III (Midlands Region)
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State of South Carolina
New 19h ago
Regional Finance Manager / Accounting - Fiscal Manager III (Midlands Region)
State of South Carolina
Lexington County, SC
Business Operations
Program Management
Project Management
$110k - $130k/yr
Hybrid
Bachelor's degree in finance
10,000+

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State of South Carolina
Regional Finance Manager / Accounting - Fiscal Manager III (Lowcounty Region)
We won't show you this job again
State of South Carolina
New 19h ago
Regional Finance Manager / Accounting - Fiscal Manager III (Lowcounty Region)
State of South Carolina
Lexington County, SC
Business Operations
Program Management
Project Management
$110k - $130k/yr
Hybrid
Bachelor's degree in finance
10,000+

Have you applied for this role?

See All 51 Regional Manager Jobs in South Carolina

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Regional Manager Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
5 jobs
Charleston
5 jobs
Greenville
5 jobs
Laurens
4 jobs
Myrtle Beach
3 jobs
Rock Hill
2 jobs
Spartanburg
2 jobs
Alcolu
1 job
Lugoff
1 job

Regional Manager Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • State of South Carolina
    State of South Carolina10
  • Walmart
    Walmart5
  • Aspen Dental
    Aspen Dental3
  • W
    WGP Property Management3
  • AVI Foodsystems
    AVI Foodsystems2

Top Industries Hiring

  • Retail
  • Manufacturing
  • Medical Devices

What South Carolina Employers Look For

The qualifications that appear most often in regional manager jobs across South Carolina.

  • Bachelor's degree in business administration, management, or a related field required
  • Five or more years of multi-unit or multi-site management experience strongly preferred
  • Demonstrated ability to lead, coach, and develop teams across multiple locations
  • Proven ability to manage P&L, budgets, and financial performance at a regional level
  • Proficiency with CRM platforms, ERP systems, or operations management software
  • Willingness to travel regularly within an assigned South Carolina territory

Regional Manager Jobs in South Carolina: Frequently Asked Questions

How do you become a regional manager in South Carolina?

Most regional managers in South Carolina move into the role after building several years of experience as a store manager, district supervisor, or department director within their industry. South Carolina does not require a state-issued license for general regional management, but roles in regulated industries like healthcare or financial services may require relevant professional credentials. A bachelor's degree in business or a related field is the standard baseline most South Carolina employers expect.

How much do regional managers make in South Carolina?

Regional managers in South Carolina earn a median of about $106,080 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $56,520 for the lowest 10% to over $219,350 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire regional managers in South Carolina?

Companies currently hiring regional managers in South Carolina include State of South Carolina, Walmart, and Aspen Dental, per current listings on Migrate Mate as of August 2026. South Carolina's mix of manufacturing anchors, large healthcare systems, and national retail chains creates steady regional manager demand across multiple industries throughout the state.

Which South Carolina cities have the most regional manager jobs?

The cities with the most regional manager openings in South Carolina are Lexington County, Columbia, and Charleston. Columbia draws hiring from state government contractors, healthcare networks, and financial services firms, Charleston benefits from its port-driven logistics and hospitality sectors, and Greenville reflects the manufacturing and automotive supplier base concentrated in the Upstate region.

Are there remote regional manager jobs in South Carolina?

Yes, but they're rare. Regional management typically requires in-person presence across multiple locations, which limits full-remote arrangements. About 71% of regional manager openings tied to South Carolina are remote or hybrid as of August 2026, and those positions tend to concentrate in functions like sales management or account-based operations where physical oversight of a facility is not required.

How can I get hired as a regional manager in South Carolina with little or no experience?

The most realistic entry path is building a record in a single-unit management role first. Large South Carolina employers such as Prisma Health, Michelin, and national retailers operating in Columbia and Greenville run management development programs that advance store managers and department leads into multi-site roles. Moving from an assistant manager, operations supervisor, or area coordinator title into a district or regional role is the common progression, and a business degree or PMP credential strengthens a candidate's case considerably.

Where can I find and apply to regional manager jobs in South Carolina?

You can find and apply to regional manager jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the listings, find roles that match your background and location preferences, and apply directly to the ones that fit.

See All 51 Regional Manager Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Regional Manager Jobs