Regional Manager Jobs in South Carolina
Regional Manager jobs in South Carolina are open across Greenwood, Charleston, and Fort Mill and other South Carolina metros, with employers like Self Regional Healthcare, Aspen Dental, and Atlas Copco hiring at every experience level. Find a role that fits below and apply directly.
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INTRODUCTION
At Aspen Dental, we put You first, offering the security and job stability that comes with working with a world-class dental service organization (DSO). Our best-in-class training program, competitive compensation, and opportunity for advancement will help you thrive in your career. When you join our team as a Regional Manager, you will have the opportunity to give back to communities and positively affect patients’ lives.
Salary: $85,000 + / year + incentive opportunity
At Aspen Dental, we put You First. We offer:
- Career development and growth opportunities with our best-in-class training program to support you at every stage of your career
- A fun and supportive culture that encourages collaboration and innovation
- Free Continuing Education (CE) through TAG U
- A generous benefits package that includes paid time off, health, dental, vision, and 401(k) savings plan with match
HOW YOU’LL MAKE A DIFFERENCE
As a Regional Manager, you will oversee practice operations for a group of 6-10 Aspen Dental branded practices. You will play a critical role spearheading growth and process improvement initiatives, own full profit and loss responsibility, and develop close working partnerships with the entire practice staff.
- Travel to nearby offices to support practice operations (3-4 days per week).
- During training, you will be onsite at an Aspen Dental location 5 days per week.
- Provide training and development support to ensure all practice staff demonstrate knowledge of the business model, operating procedures, and protocols.
- In partnership with the talent acquisition team and the office manager, evaluate and communicate staffing needs to enable effective hiring and onboarding experiences for new team members.
- Support daily office operations within the region as necessary.
QUALIFICATIONS
- Availability to relocate after 6 months of local training is required (relocation assistance provided).
- Management experience overseeing multiple locations in the retail or health care industry.
- Prior profit and loss responsibility and the ability to interpret and act upon financial statements.
- Knowledge of Microsoft Office business applications.
- Strong communication and interpersonal skills, with the ability to build rapport with patients and employees of all ages and backgrounds.
- Commitment to ongoing learning and professional development for yourself and your team.
- Bachelor’s degree preferred.
- As this position requires daily travel to assigned offices, you must maintain a valid non-restricted driver’s license and appropriate insurance or the ability to be insured under the employer’s fleet insurance program (for those assigned a Company fleet vehicle). The Company reserves the right to request and review your Motor Vehicle Record at any time, according to state requirements.
ADMI Corp., d/b/a TAG-The Aspen Group, its affiliates, related companies and independently owned supported clinical practices are proud to be Equal Opportunity Employers and welcome everyone to apply. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
See All 14 Regional Manager Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Regional Manager JobsRegional Manager Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Regional Manager Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Self Regional Healthcare5

- Aspen Dental3

- Atlas Copco2

- Capital Vacations1

- Holiday Inn Club Vacations1

Top Industries Hiring
- Healthcare & Medical Services8
- Hospitality & Tourism2
- Manufacturing2
- Investment & Asset Management1
What South Carolina Employers Look For
The qualifications that appear most often in regional manager jobs across South Carolina.
- 5+ years of multi-unit or district management experience in a relevant industry
- Demonstrated ability to manage a P&L across multiple locations or territories
- Experience leading, recruiting, and developing teams of 20 or more employees
- Proficiency with operations software, CRM platforms, or industry-specific reporting tools
- Bachelor's degree in business, operations, management, or a related field
- Willingness to travel regularly within an assigned geographic territory
Regional Manager Jobs in South Carolina: Frequently Asked Questions
How many regional manager jobs are there in South Carolina?
There are 14+ regional manager openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Greenwood, Charleston, and Fort Mill. New positions post regularly as employers across South Carolina hire.
How much do regional managers make in South Carolina?
Regional managers in South Carolina earn a median of about $106,080 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $56,520 for the lowest 10% to over $219,350 for the top 10%. Pay rises with experience, specialty, and employer.
Which South Carolina cities have the most regional manager jobs?
Greenwood, Charleston, and Fort Mill have the most regional manager openings in South Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire regional managers in South Carolina?
Employers hiring regional managers in South Carolina include Self Regional Healthcare, Aspen Dental, and Atlas Copco, based on current listings on Migrate Mate as of June 2026.
Are there remote regional manager jobs in South Carolina?
Yes. About 21% of regional manager openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.
How do I apply for regional manager jobs in South Carolina?
You can apply to regional manager jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.
See All 14 Regional Manager Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Regional Manager Jobs