Sales Director Jobs in Minnesota
Sales Director jobs in Minnesota are concentrated in the Twin Cities metro, with additional demand in Rochester and Duluth, where companies like Medtronic, UnitedHealth Group, and Cargill maintain deep sales operations. The most consistent openings are in medical device and healthcare technology sales, enterprise software, and agricultural and food industry accounts, reflecting Minnesota's dominant industries. Candidates at every level from regional manager to VP of Sales find active pipelines here, making the Twin Cities one of the more active markets in the Midwest. Scan the live roles below and apply to whichever ones fit.
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Description
You provide the vision, set the pace and inspire success.
As a Regional Sales Director, you will lead a high-performing field based commercial sales team and support the growth of an emerging biotechnology organization committed to advancing innovative medicines. You will be responsible for developing and executing regional business strategies, driving sales performance, and fostering strong partnerships with healthcare professionals and key stakeholders. Reporting to the National Business Director, you will utilize your experience and relationships in Hospitals/IDN to recruit, mentor, and develop a team focused on delivering exceptional customer engagement and commercial results for a rare disease product launch. In this role, you will be an integral part of a building a high performing Key Account Management team. You will:
- Hire, develop, train, coach, assess, motivate and retain a highly performing team, strengthening individual capabilities and elevating overall performance to meet the evolving needs of customers and drive business results.
- Develop and implement comprehensive business plans that support the successful execution of a launch strategy Ensure the development and pull through of Strategic Account plans with each KAM.
- Cultivate effective relationships with Key influencers to possibly include, C-Suite and administrative roles within an account (not limited to CEO, CFO, CMO, Pharmacy Director, Medical Director, Case Management, Dir. of Quality, Industry Relations, Technology Dir, etc.).
- Develop and present in conjunction with the team sound clinical, pharmaco-economic and business presentations to appropriate customers based on mutual needs/benefits.
- Review and analyze product performance at the regional & local level and communicate account performance broadly with key internal stakeholders.
- Build a culture of accountability through effective performance coaching, talent development, and succession planning to create a high-performing sales organization.
- Analyze market dynamics, referral patterns, account segmentation, and business trends to identify opportunities and optimize regional execution strategies.
- Monitor leading performance indicators and demand-generation activities to proactively adjust regional strategies and maximize commercial results.
- Ensure consistent execution of patient pull-through initiatives designed to support patient identification, access, treatment initiation, and ongoing therapy engagement.
Essential Requirements:
- 10+ years of proven success in Life Sciences.
- 4+ years of first-line sales leadership experience with 2+ years in navigating hospital systems, Integrated Delivery Networks (IDNs or large health systems.
- Experience as a launch leader within rare disease, oncology, immunology, or specialty biopharmaceutical markets, with experience driving commercial readiness and execution in complex healthcare environments
- Strong background in oncology and/or specialty therapeutics, with a demonstrated ability to engage diverse clinical stakeholders and influence treatment adoption.
- Deep understanding of P&T Committee processes, formulary decision-making, and institutional market access dynamics.
- Demonstrated ability to operate as a player-coach, balancing strategic leadership, field engagement, and team development.
- Experience leading cross-functional launch readiness initiatives, partnering effectively with Medical Affairs, Market Access, Marketing, Operations, and other key stakeholders. Proven success collaborating with payer and access teams to support prior authorization processes, coverage policies, reimbursement strategies, and buy-and-bill environments.
- Expertise in account segmentation, referral network mapping, demand planning, and identification of leading business indicators to drive market development and execution.
- Strong understanding of the patient journey and treatment pull-through process, including patient identification, access and reimbursement support, treatment initiation, scheduling, and ongoing therapy management.
- Demonstrated ability to build strategic business plans, drive execution, and deliver results in highly competitive and evolving specialty markets.
The annual base salary for this position ranges from $220,000 to $227,500. The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role. In addition, some positions may include a company car or car allowance and eligibility to earn commissions/bonus based on company and / or individual performance.
At Syneos Health, we are dedicated to building a diverse, inclusive and authentic workplace. If your past experience doesn’t align perfectly, we encourage you to apply anyway. At times, we will consider transferable skills from previous roles. We also encourage you to join our Talent Network to stay connected to additional career opportunities.
Why Syneos Health? Each life we positively impact makes our work worthwhile. By joining one of our field medical teams, you will partner with some of the most talented clinicians in the industry and be reminded why you chose a career in healthcare. The diversification and breadth of our new and existing partnerships create a multitude of career paths and employment opportunities. Join our game-changing, global company dedicated to creating better, smarter, faster ways to get biopharmaceutical therapies to patients. Experience the thrill of knowing that your everyday efforts are contributing to improving patients’ lives around the world.
Work Here Matters Everywhere | How are you inspired to change lives?
Syneos Health companies are affirmative action/equal opportunity employers (Minorities/Females/Veterans/Disabled)
At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position will include a competitive compensation package, Health benefits to include Medical, Dental and Vision, Company match 401k, flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos Health complies with all applicable federal, state, and municipal paid sick time requirements.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
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See All 51 Sales Director Jobs in Minnesota
Find roles in Minnesota that match your experience and apply in just a few clicks.
Find Sales Director JobsSales Director Jobs by City in Minnesota
Where Minnesota roles are concentrated, by current openings.
Sales Director Job Market in Minnesota
A snapshot from current Minnesota openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Insurance
- Cybersecurity
- Technology & Software
What Minnesota Employers Look For
The qualifications that appear most often in sales director jobs across Minnesota.
- Bachelor's degree in business, marketing, or a related field required
- Seven or more years of progressive B2B or enterprise sales experience
- Demonstrated ability to build and lead a quota-carrying sales team
- Experience selling into healthcare, technology, or manufacturing verticals preferred
- Proficiency with CRM platforms such as Salesforce or Microsoft Dynamics
- Strong forecasting skills and comfort presenting to C-suite stakeholders
Sales Director Jobs in Minnesota: Frequently Asked Questions
How do you become a sales director in Minnesota?
Most sales director roles in Minnesota require a bachelor's degree in business, marketing, or a related field, combined with several years of sales experience that includes team leadership. There is no state-issued license required to work as a sales director in Minnesota. Employers in healthcare technology and medical devices often look for candidates who understand Minnesota's regulated industries, and an MBA from a Minnesota institution like the Carlson School of Management can strengthen a candidacy.
How much do sales directors make in Minnesota?
Sales directors in Minnesota earn a median of about $151,670 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $79,900 for the lowest 10% to over $258,460 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire sales directors in Minnesota?
Minnesota sales director roles are posted by Lifespark, Wolters Kluwer, and ZURU and others right now, based on current listings on Migrate Mate as of November 2026. Minnesota's concentration of Fortune 500 headquarters, particularly in healthcare, financial services, and agriculture, means large enterprise employers drive a significant share of the openings.
Which Minnesota cities have the most sales director jobs?
Minneapolis, Eagan, and Saint Paul have the most sales director openings in Minnesota. The Twin Cities account for the bulk of postings because of the dense concentration of corporate headquarters and regional offices there, while Rochester draws openings tied to the Mayo Clinic health system and its surrounding medical technology ecosystem.
Are there remote sales director jobs in Minnesota?
Yes, and more than many senior roles, since sales director work often centers on strategy, pipeline oversight, and client relationships that can be managed remotely. About 68% of sales director openings tied to Minnesota are remote or hybrid as of November 2026, reflecting broader flexibility at the director level. Roles tied to hands-on territory management or in-person enterprise accounts tend to require more consistent on-site presence.
How can I get hired as a sales director in Minnesota with little or no experience?
The most realistic path is to start in an account executive or senior sales representative role at a large Minnesota employer and build a record of quota attainment before moving into management. Companies like Medtronic, Ecolab, and UnitedHealth Group run structured sales development programs that pipeline talent into leadership. Earning a leadership role on a smaller team, such as a team lead or inside sales manager at a mid-size Twin Cities firm, is a common bridge into a full director title.
Where can I find and apply to sales director jobs in Minnesota?
You can find and apply to sales director jobs in Minnesota on Migrate Mate, which lists current Minnesota openings updated regularly. Search the listings to find roles that match your industry background and territory preferences, then apply directly to the ones that fit your experience.
See All 51 Sales Director Jobs in Minnesota
Find roles in Minnesota that match your experience and apply in just a few clicks.
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