Regional Sales Manager Jobs in Illinois
Regional Sales Manager jobs in Illinois are in strong demand, with concentrated hiring in manufacturing, technology, healthcare products, and food and beverage distribution across seniority levels from territory sales lead through senior regional director. Chicago anchors the market, with secondary hiring in Peoria and Rockford, where employers like Caterpillar, Abbott, and Kraft Heinz maintain lasting regional structures that regularly bring on sales leadership. The most sought-after specialties in Illinois are B2B industrial sales, medtech device sales, and distribution channel management. Find a role that fits below and apply directly.
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Job Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
What you will do
Let’s do this. Let’s change the world. In this vital role, you will lead the regional sales organization for UPLIZNA in Neurology (gMG and NMOSD), translating brand strategy into focused execution and delivering results through a high-performing team.
The Regional Sales Director (RSD) is accountable for the leadership, performance and development of the UPLIZNA Neurology sales organization across the assigned region. This leader will establish regional strategy, create clarity around priorities and expectations, and develop District Managers and field teams to execute with excellence. The RSD will operate as a senior commercial leader and strategic business partner, using market insights, customer understanding and cross-functional collaboration to identify opportunities, remove barriers and drive sustainable performance in a complex rare disease marketplace.
- Lead the region as a business, translating UPLIZNA brand priorities into a focused regional strategy, clear execution imperatives, measurable standards and disciplined operating rhythms.
- Deliver business results through others by equipping District Managers as force multipliers, setting clear performance expectations, using leading indicators to identify opportunities and risks early, and driving timely action and accountability.
- Coach and develop District Managers through a consistent observe, diagnose, practice and follow-up approach that strengthens leadership capability, business acumen, coaching quality, decision-making and representative performance.
- Build and sustain a high-performing, inclusive and compliant culture grounded in Amgen values, patient focus, operational excellence, accountability, scientific integrity and clear, credible leadership communication.
- Attract, select, onboard, retain and develop future-ready talent; establish meaningful development priorities for leaders and maintain strong succession and bench plans for critical roles across the region.
- Synthesize performance data, access dynamics, customer needs, competitive signals and field intelligence to generate decision-ready insights, identify root causes and dynamically adjust regional plans and resources.
- Maintain deep knowledge of gMG and NMOSD, the UPLIZNA clinical profile, the treatment landscape and evolving customer and market dynamics, translating that understanding into relevant regional strategy and field direction.
- Develop strong relationships with key customers and stakeholders and provide visible leadership at priority regional and national congresses, conferences and other strategic customer engagements.
- Lead with an enterprise mindset, appropriately and compliantly orchestrating Marketing, Market Access, Patient Services, Medical, Training, Commercial Operations, HR and other partners around shared brand and business objectives.
- Anticipate, adapt and lead through change by monitoring early signals, clarifying what is changing and why, making thoughtful start-stop trade-offs, and keeping teams focused, aligned and accountable through ambiguity.
- Allocate regional resources, operating expenses and program investments to the highest-priority opportunities, balancing patient impact, business performance, risk and established budget expectations.
- Ensure all regional activities are conducted in accordance with applicable laws, regulations, company policies and Amgen compliance, ethics and safety standards, reinforcing responsible performance and appropriate business conduct.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The Regional Sales Director professional we seek is a strategic, results-oriented people leader with these qualifications.
Basic Qualifications:
Doctorate degree and 4 years of collective account management, sales, marketing and/or commercial experience
OR
Master’s degree and 8 years of collective account management, sales, marketing and/or commercial experience
OR
Bachelor’s degree and 10 years of collective account management, sales, marketing and/or commercial experience
In addition to meeting at least one of the above requirements, candidates must have at least 4 years of experience directly managing people and/or leadership experience leading teams, projects or programs, or directing the allocation of resources. Managerial experience may run concurrently with the required commercial experience referenced above.
Preferred Qualifications:
- Bachelor’s degree required; advanced degree or MBA preferred.
- 5+ years of sales leadership experience, with demonstrated success developing people leaders and delivering business results through multi-level field organizations.
- 10+ years of biotech/pharmaceutical commercial experience; rare disease, neurology, specialty biologic and/or buy-and-bill experience strongly preferred.
- Demonstrated success attracting and developing talent, building succession pipelines, creating healthy high-performance cultures and leading organizations through growth and change.
- Strong insight and strategic agility, including the ability to synthesize multiple data sources and market signals, diagnose business drivers and translate insights into focused regional strategy and resource decisions.
- Proven ability to translate brand priorities into clear execution standards, leading indicators, operating rhythms and timely performance actions.
- Strong executive presence and communication skills, with the ability to simplify complex strategy, inspire followership and influence stakeholders at varying organizational levels.
- Demonstrated enterprise mindset and ability to orchestrate cross-functional partners in a complex matrix environment while maintaining clear decision rights, accountability and compliant ways of working.
- Strong understanding of the U.S. pharmaceutical regulatory and compliance environment.
- Requires approximately 60% travel, including some overnight and weekend commitments.
- Proficient in Microsoft Office.
- Professional, proactive demeanor.
- Strong interpersonal skills.
- Excellent written and verbal communication skills.
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
and make a lasting impact with the Amgen team.
careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
See All 112+ Regional Sales Manager Jobs in Illinois
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Find Regional Sales Manager JobsRegional Sales Manager Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Regional Sales Manager Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Staffing & Recruiting
- Retail
- Automotive
- Consumer Goods
- Healthcare & Medical Services
What Illinois Employers Look For
The qualifications that appear most often in regional sales manager jobs across Illinois.
- Bachelor's degree in business, marketing, or a related field required by most Illinois employers
- Five or more years of direct sales experience with demonstrated revenue growth
- Proven ability to manage and coach a multi-state or multi-territory sales team
- Experience selling into Illinois's key industries: manufacturing, healthcare, or food distribution
- Proficiency with CRM platforms such as Salesforce or Microsoft Dynamics
- Willingness to travel regularly throughout an assigned Illinois or Midwest territory
Regional Sales Manager Jobs in Illinois: Frequently Asked Questions
How do you become a regional sales manager in Illinois?
The path to a regional sales manager role in Illinois typically starts with a bachelor's degree in business, marketing, or a field aligned to the industry you want to sell into, followed by several years as an individual contributor in outside or B2B sales. Illinois does not require a state-issued license for sales management, so advancement depends on building a record of quota achievement, then moving into team-lead or district manager roles before stepping up to regional responsibility.
How much do regional sales managers make in Illinois?
Regional sales managers in Illinois earn a median of about $155,280 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $78,760 for the lowest 10% to over $282,890 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire regional sales managers in Illinois?
Employers hiring regional sales managers in Illinois right now include Abbott, Masters Transportation, and Jobot, based on current listings on Migrate Mate as of November 2026. Illinois's deep base of manufacturing, healthcare, and consumer goods headquarters means regional sales leadership roles turn over regularly, especially in the Chicago metro corridor.
Which Illinois cities have the most regional sales manager jobs?
Chicago, Illinois, and Elgin account for the largest share of regional sales manager openings in Illinois. Chicago's concentration of corporate headquarters and distribution networks drives the bulk of demand, while Peoria and Rockford generate consistent openings through large industrial employers like Caterpillar and the dense manufacturing supplier base that surrounds them.
Are there remote regional sales manager jobs in Illinois?
Yes, and more than some might expect, because regional sales managers spend much of their time on the road rather than in a fixed office, making the administrative side of the role easy to handle remotely. About 78% of regional sales manager openings tied to Illinois are remote or hybrid as of November 2026. The portions most suited to remote work are pipeline reporting, team coaching calls, and forecasting, while client visits and field rides with reps remain in-person.
How can I get hired as a regional sales manager in Illinois with little or no experience?
The most realistic entry path is landing an outside sales representative or territory account manager role at a large Illinois employer, then building toward promotion. Companies like Cintas, Grainger, and Sysco Illinois operations run structured sales development programs that move high performers into team-lead assignments within a few years. A strong start also comes from transferring out of adjacent roles in account management, sales operations, or customer success, where you already influence revenue outcomes. Earning a Certified Sales Professional credential can give your application an edge when competing against candidates with longer direct sales tenures.
Where can I find and apply to regional sales manager jobs in Illinois?
You can find and apply to regional sales manager jobs in Illinois on Migrate Mate, which lists current Illinois openings across industries and hiring metros. Find the roles that fit your experience and apply directly to the ones that match.
See All 112+ Regional Sales Manager Jobs in Illinois
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