Research Associate Jobs in USA with Visa Sponsorship
Research associate positions are regularly sponsored by universities, hospitals, pharmaceutical companies, and biotech firms. H-1B visa is the most common visa route, and positions at universities and nonprofit research organizations are cap-exempt from the H-1B lottery. J-1 visa research scholar visas are also widely used. A master's or Ph.D. significantly strengthens both your candidacy and your visa petition. For detailed occupation requirements, see the O*NET profile.
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Get Access To All JobsINTRODUCTION
What if… you could pioneer a new approach to designing life's most essential molecules?
FL116, backed by Flagship Pioneering, is an early-stage biotechnology company transforming the way biomolecules are synthesized. Our innovative platform has the potential to transform how critical research, diagnostic, and therapeutic molecules are manufactured. We are seeking passionate problem solvers ready to make a profound impact on biotechnology and therapeutic innovation.
Position Summary
Senior Research Associate – Molecular Biology & Sequencing
We are seeking a motivated, detail-oriented, and technically strong Sr. RA to join our Assay Development team. This role owns the next-generation sequencing and high-throughput cloning that generate the design-build-test-learn data powering our platform —
You will run Illumina MiSeq i100 and NextSeq 2000 instruments end to end, build and QC large pooled variant libraries, and partner closely with enzyme engineering, chemical biology, and computational colleagues to turn sequencing output into actionable insight.
This is an exciting opportunity to build and own core molecular biology capabilities within a fast-paced, collaborative startup. You are a hands-on experimentalist who thrives on rigorous execution, cares about data quality and sample provenance, and is eager to grow with a rapidly evolving technology platform.
Key Responsibilities
- Sequencing: Perform NGS library preparation, QC, and end-to-end operation of Illumina MiSeq i100 and NextSeq 2000 platforms, including run setup and troubleshooting
- Cloning: Execute high-throughput molecular cloning workflows (Gibson, Golden Gate, and related methods) to build constructs and variant libraries at scale
- Pooled library assembly and QC: Assemble, quantify, and quality-control large pooled variant libraries, ensuring coverage, diversity, and representation meet project requirements
- Sample management and tracking: Own sample management, barcoding, and data/metadata tracking across both sequencing and cloning workflows, maintaining accurate records in ELN/LIMS systems
- Develop, optimize, and document robust, scalable protocols; identify and implement opportunities for throughput, cost, and quality improvements
- Process and interpret raw sequencer output, working with computational colleagues to convert reads into actionable insights for platform and pipeline decisions
- Collaborate closely with cross-functional partners across enzyme science, chemical biology, and machine learning to ensure sequencing and cloning capabilities meet downstream needs
- Maintain rigorous experimental documentation, communicate results clearly, and contribute to knowledge sharing and lab best practices
- Comply with laboratory safety protocols and best practices in reagent, sample, and biohazard handling
Qualifications
- B.S. in Biology, Biochemistry, Molecular Biology, or a related discipline with 5+ years of relevant laboratory experience; M.S. with 3+ years.
- Extensive hands-on experience performing NGS library preparation, library QC, and sequencer operation on Illumina MiSeq and NextSeq platforms
- Hands-on experience performing Gibson, Golden Gate, and related molecular cloning workflows
- Demonstrated ability to generate high-quality, reproducible data with rigorous documentation and sample tracking
- Strong organizational skills and attention to detail, with the ability to manage multiple parallel workstreams
- Clear communicator who works effectively in fast-paced, collaborative laboratory environments
Preferred Qualifications
- Experience characterizing the products of nucleic acid modifying enzymes via sequencing and other analytical methods (LC-MS, HPLC, etc.)
- Experience converting raw sequencer output into actionable insights, including familiarity with demultiplexing, read QC, and basic analysis tooling (e.g., command line, Python, or R)
- Experience applying high-throughput cloning and NGS data to enzyme engineering projects
- Experience running high-throughput enzyme assays using basic lab automation (e.g., liquid handlers) and plate readers
- Experience constructing and testing large variant libraries through pooled functional testing (e.g., yeast surface display or a related method)
- Familiarity with electronic lab notebooks (ELNs), LIMS, or related data-management tools
Who You Are
- Innovative Pioneer: You are excited by the opportunity to explore new scientific frontiers and to build the molecular biology capabilities that unlock a novel synthesis platform.
- Collaborative Contributor: You work effectively across teams, communicate clearly, and value shared success in a highly interdisciplinary environment.
- Inventive Problem Solver: You approach challenges with curiosity and creativity, troubleshooting from first principles to develop elegant, reliable experimental solutions.
- Rigorous Operator: You take pride in clean data, careful sample provenance, and protocols others can trust and reproduce.
- Mission-Driven Individual: You are motivated by the opportunity to fundamentally change how biomolecules are synthesized and to impact human health and biotechnology.
More About Flagship Pioneering
Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, generating billions in value. Flagship companies are known for addressing humanity's most pressing challenges and advancing innovative solutions with global impact.
We are an equal opportunity employer and are dedicated to building diverse and inclusive teams. If you have some of the qualifications listed above but not all, we still encourage you to apply. We value passion, experience in many forms, and unique backgrounds.
Come pioneer the future with us.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
The salary range for this role is $81,000 - $107,250. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. FL116 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL116's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
INTRODUCTION
What if… you could pioneer a new approach to designing life's most essential molecules?
FL116, backed by Flagship Pioneering, is an early-stage biotechnology company transforming the way biomolecules are synthesized. Our innovative platform has the potential to transform how critical research, diagnostic, and therapeutic molecules are manufactured. We are seeking passionate problem solvers ready to make a profound impact on biotechnology and therapeutic innovation.
Position Summary
Senior Research Associate – Molecular Biology & Sequencing
We are seeking a motivated, detail-oriented, and technically strong Sr. RA to join our Assay Development team. This role owns the next-generation sequencing and high-throughput cloning that generate the design-build-test-learn data powering our platform —
You will run Illumina MiSeq i100 and NextSeq 2000 instruments end to end, build and QC large pooled variant libraries, and partner closely with enzyme engineering, chemical biology, and computational colleagues to turn sequencing output into actionable insight.
This is an exciting opportunity to build and own core molecular biology capabilities within a fast-paced, collaborative startup. You are a hands-on experimentalist who thrives on rigorous execution, cares about data quality and sample provenance, and is eager to grow with a rapidly evolving technology platform.
Key Responsibilities
- Sequencing: Perform NGS library preparation, QC, and end-to-end operation of Illumina MiSeq i100 and NextSeq 2000 platforms, including run setup and troubleshooting
- Cloning: Execute high-throughput molecular cloning workflows (Gibson, Golden Gate, and related methods) to build constructs and variant libraries at scale
- Pooled library assembly and QC: Assemble, quantify, and quality-control large pooled variant libraries, ensuring coverage, diversity, and representation meet project requirements
- Sample management and tracking: Own sample management, barcoding, and data/metadata tracking across both sequencing and cloning workflows, maintaining accurate records in ELN/LIMS systems
- Develop, optimize, and document robust, scalable protocols; identify and implement opportunities for throughput, cost, and quality improvements
- Process and interpret raw sequencer output, working with computational colleagues to convert reads into actionable insights for platform and pipeline decisions
- Collaborate closely with cross-functional partners across enzyme science, chemical biology, and machine learning to ensure sequencing and cloning capabilities meet downstream needs
- Maintain rigorous experimental documentation, communicate results clearly, and contribute to knowledge sharing and lab best practices
- Comply with laboratory safety protocols and best practices in reagent, sample, and biohazard handling
Qualifications
- B.S. in Biology, Biochemistry, Molecular Biology, or a related discipline with 5+ years of relevant laboratory experience; M.S. with 3+ years.
- Extensive hands-on experience performing NGS library preparation, library QC, and sequencer operation on Illumina MiSeq and NextSeq platforms
- Hands-on experience performing Gibson, Golden Gate, and related molecular cloning workflows
- Demonstrated ability to generate high-quality, reproducible data with rigorous documentation and sample tracking
- Strong organizational skills and attention to detail, with the ability to manage multiple parallel workstreams
- Clear communicator who works effectively in fast-paced, collaborative laboratory environments
Preferred Qualifications
- Experience characterizing the products of nucleic acid modifying enzymes via sequencing and other analytical methods (LC-MS, HPLC, etc.)
- Experience converting raw sequencer output into actionable insights, including familiarity with demultiplexing, read QC, and basic analysis tooling (e.g., command line, Python, or R)
- Experience applying high-throughput cloning and NGS data to enzyme engineering projects
- Experience running high-throughput enzyme assays using basic lab automation (e.g., liquid handlers) and plate readers
- Experience constructing and testing large variant libraries through pooled functional testing (e.g., yeast surface display or a related method)
- Familiarity with electronic lab notebooks (ELNs), LIMS, or related data-management tools
Who You Are
- Innovative Pioneer: You are excited by the opportunity to explore new scientific frontiers and to build the molecular biology capabilities that unlock a novel synthesis platform.
- Collaborative Contributor: You work effectively across teams, communicate clearly, and value shared success in a highly interdisciplinary environment.
- Inventive Problem Solver: You approach challenges with curiosity and creativity, troubleshooting from first principles to develop elegant, reliable experimental solutions.
- Rigorous Operator: You take pride in clean data, careful sample provenance, and protocols others can trust and reproduce.
- Mission-Driven Individual: You are motivated by the opportunity to fundamentally change how biomolecules are synthesized and to impact human health and biotechnology.
More About Flagship Pioneering
Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, generating billions in value. Flagship companies are known for addressing humanity's most pressing challenges and advancing innovative solutions with global impact.
We are an equal opportunity employer and are dedicated to building diverse and inclusive teams. If you have some of the qualifications listed above but not all, we still encourage you to apply. We value passion, experience in many forms, and unique backgrounds.
Come pioneer the future with us.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
The salary range for this role is $81,000 - $107,250. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. FL116 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL116's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
See all 21,889+ Research Associate Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Research Associate roles.
Get Access To All JobsTips for Finding Visa Sponsorship as a Research Associate
Start at a university or nonprofit for cap-exempt H-1B processing
University research positions avoid the H-1B lottery entirely, making them the most reliable visa path for research associates. Major research universities - MIT, Stanford, Johns Hopkins, University of Michigan, UCSF - employ thousands of international researchers across every scientific discipline. Even if your long-term goal is industry, starting in academia gives you immediate work authorization without lottery risk.
Use the J-1 research scholar visa for long-term research projects
The J-1 research scholar category allows up to five years of research activity, which is longer than many initial H-1B grants. This is particularly useful for multi-year research projects or when the H-1B cap makes timing uncertain. Be aware that some J-1 categories carry a two-year home residency requirement - check your DS-2019 and plan accordingly if you intend to change visa status later.
Build an O-1 case through publications, citations, and peer review
Research associates who accumulate publications in peer-reviewed journals, high citation counts, conference presentations, and peer review invitations can build a case for O-1 extraordinary ability classification. The O-1 has no annual cap and can be filed at any time. Start documenting your scholarly contributions from day one - keep records of every publication, invited talk, grant contribution, and review request.
Target federally funded research centers for stable positions
Federally funded research and development centers (FFRDCs) like MIT Lincoln Laboratory, MITRE Corporation, Jet Propulsion Laboratory, and Sandia National Laboratories employ research associates and may be H-1B cap-exempt. These positions often come with competitive salaries, excellent benefits, and long-term project funding. Some may require security clearance eligibility, which can limit options for certain nationalities.
Network through academic conferences and professional societies
Academic hiring relies heavily on professional networks and conference connections. Present your research at relevant conferences (ACS, APS, AAAS, or discipline-specific meetings) and engage with potential PI collaborators. Many research associate positions are filled through direct PI contacts rather than formal job postings. Professional society membership also provides access to job boards with positions specifically open to international researchers.
Plan your industry transition timeline strategically
If industry R&D is your long-term goal, use your academic research associate period to build publications, develop specialized techniques, and make industry connections. Attend industry-academic conferences and apply for industry-sponsored research grants. Your academic credentials and cap-exempt start mean you may already have H-1B status that can be transferred to an industry employer when the time is right.
Frequently Asked Questions
What visa options are available for research associate positions?
Research associates have several visa paths depending on the employer. H-1B visa is common for both academic and industry research positions. J-1 visa research scholar visas allow up to five years of research at qualifying institutions. O-1 visas are available for researchers with extraordinary ability demonstrated through publications, citations, and awards. University and nonprofit research institution positions are often H-1B cap-exempt, avoiding the lottery.
Are university research associate positions cap-exempt for H-1B?
Yes, research associate and postdoctoral positions at nonprofit universities, teaching hospitals, and affiliated research institutions are H-1B cap-exempt. This means no lottery, no annual cap, and the ability to file at any time of year. This is one of the most significant advantages of academic research positions for international scientists. Some university-affiliated research institutes and hospitals maintain cap-exempt status even for non-faculty positions.
What is the difference between a research associate and a postdoctoral researcher for visa purposes?
The distinction is primarily about seniority and independence, not visa eligibility. Both typically qualify for H-1B (cap-exempt at universities) or J-1 research scholar visas. Research associates may not require a doctoral degree, while postdoctoral positions by definition require a Ph.D. or equivalent. Some universities classify both under the same visa processing procedures, though job titles and salary levels differ.
How to find Research Associate jobs with visa sponsorship?
To find Research Associate jobs with visa sponsorship, use Migrate Mate, which specializes in connecting international candidates with sponsoring employers. Research Associate roles are commonly available with H-1B, O-1, and other work visas at pharmaceutical companies, biotech firms, universities, and research institutions. These organizations frequently sponsor visas for qualified research professionals with relevant scientific backgrounds and experience.
Can research associates transition from academic to industry positions?
Yes, transitioning from academic research to industry R&D is common and often results in higher salaries and additional sponsorship options. Industry research positions at pharmaceutical, biotech, and technology companies sponsor H-1B visas through the regular cap (lottery required). If you built a strong publication record in academia, you may also qualify for an O-1 visa, which has no annual cap.
What is the prevailing wage requirement for sponsored Research Associate jobs?
When a U.S. employer sponsors a foreign worker for a work visa, they are legally required to pay at least the "prevailing wage" — the average wage paid to workers in the same occupation, in the same geographic area, with similar experience. This is set by the Department of Labor to prevent employers from hiring foreign workers at below-market rates. The prevailing wage varies significantly by role, location, and experience level — for example, a research associate in California will have a different prevailing wage than the same role in a smaller state. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search.