Data Manager Jobs in USA with Visa Sponsorship
Data Manager roles attract H-1B sponsorship from employers in healthcare, finance, and tech, where managing data infrastructure requires a specific degree background. Most positions qualify as specialty occupations, making them straightforward to sponsor under both H-1B and O-1 pathways. For detailed occupation requirements, see the O*NET profile.
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INTRODUCTION
Eliassen Group and our client – a small, clinical-stage biotech focused on cardiovascular medicines – are seeking an experienced Clinical Data Manager to work remotely (or hybrid, in Princeton, NJ or San Francisco, CA) for a 1-year (extendable) engagement. You will be fully dedicated to our client and must be a Clinical Data Manager in the pharma/biotech industry with sponsor-side, CRO oversight experience.
DUTIES/EXPECTATIONS OF THIS ROLE
The Clinical Data Manager is responsible for leading the clinical data management activities for an assigned cardiovascular clinical trial including case report form design, electronic data capture (EDC) database development, processing external data, oversight of medical coding, data review, and database close/lock procedures in accordance with SOPs, Good Clinical Practice, and ICH Guidelines. The position is responsible for ensuring data management timelines and quality for their projects within the data management/clinical operations team.
Database Development/Management
- Protocol review
- Develop or review the database definition file to oversee the creation of CRFs/eCRFs. Data Validation Plans, and Edit Check Specifications
- Perform or oversee User Acceptance Testing (UAT) of the eCRFs and Edit Checks for the database in development
- Manage change requests during the course of the trial after the database is Live
Document/Documentation Development
- Review CRF/eCRF for outsourced trials; generating queries as needed
- Review edit check specifications for outsourced trials
- Review the Data Management Plan (DMP) for outsourced trials
- Review study-specific Manual Review Guidelines for outsourced trials
- Oversee Data Transfer Agreements with ancillary vendors
Data Management/Review
- Review and ensure all queries are resolved for outsourced trials; SAE reconciliation
- Review data listings
- Manage cross-functional reviews of clinical data to identify potential safety signals and support regulatory reporting (DSUR, SUSAR etc.)
- Provide Data Management summary reports to management and Clinical Operations; ad hoc reports from the database, as requested
- Ensure that the database is closed and locked at the end of the trial
- Resolve complex data issues to support timely decision-making for interim analyses
MUST HAVES – QUALIFICATION SUMMARY
- At least 5 years’ experience (functioning at the “manager” level); will report to a Lead (at the Associate Director level)
- A degree is preferred, but not required
- Cardiovascular experience is preferred, but not required
- Must have experience with CRO oversight of data management activities for Ph III studies
TRAVEL & LOCATION
- None, 100% fully remote/home-based
- There is a preference for people who are local to the Princeton, NJ or San Francisco, CA locations
START & TERM
- Start immediately following thorough screening and interview and background check – late April
- 1-year contract (could easily extend)
RATE
Competitive compensation
“Skills, experience, and other compensable factors will be taken into account when determining pay rate. The pay range provided in this posting is a reflection of a W2 hourly rate; other employment options may be available that may result in pay outside of the provided range.”
“W2 employees of Eliassen Group who are regularly scheduled to work 30 or more hours per week are eligible for the following benefits: medical (choice of 3 plans), dental, vision, pre-tax accounts, other voluntary benefits including life and disability insurance, 401(k) with match, and sick time if required by law in the worked-in state/locality.”

INTRODUCTION
Eliassen Group and our client – a small, clinical-stage biotech focused on cardiovascular medicines – are seeking an experienced Clinical Data Manager to work remotely (or hybrid, in Princeton, NJ or San Francisco, CA) for a 1-year (extendable) engagement. You will be fully dedicated to our client and must be a Clinical Data Manager in the pharma/biotech industry with sponsor-side, CRO oversight experience.
DUTIES/EXPECTATIONS OF THIS ROLE
The Clinical Data Manager is responsible for leading the clinical data management activities for an assigned cardiovascular clinical trial including case report form design, electronic data capture (EDC) database development, processing external data, oversight of medical coding, data review, and database close/lock procedures in accordance with SOPs, Good Clinical Practice, and ICH Guidelines. The position is responsible for ensuring data management timelines and quality for their projects within the data management/clinical operations team.
Database Development/Management
- Protocol review
- Develop or review the database definition file to oversee the creation of CRFs/eCRFs. Data Validation Plans, and Edit Check Specifications
- Perform or oversee User Acceptance Testing (UAT) of the eCRFs and Edit Checks for the database in development
- Manage change requests during the course of the trial after the database is Live
Document/Documentation Development
- Review CRF/eCRF for outsourced trials; generating queries as needed
- Review edit check specifications for outsourced trials
- Review the Data Management Plan (DMP) for outsourced trials
- Review study-specific Manual Review Guidelines for outsourced trials
- Oversee Data Transfer Agreements with ancillary vendors
Data Management/Review
- Review and ensure all queries are resolved for outsourced trials; SAE reconciliation
- Review data listings
- Manage cross-functional reviews of clinical data to identify potential safety signals and support regulatory reporting (DSUR, SUSAR etc.)
- Provide Data Management summary reports to management and Clinical Operations; ad hoc reports from the database, as requested
- Ensure that the database is closed and locked at the end of the trial
- Resolve complex data issues to support timely decision-making for interim analyses
MUST HAVES – QUALIFICATION SUMMARY
- At least 5 years’ experience (functioning at the “manager” level); will report to a Lead (at the Associate Director level)
- A degree is preferred, but not required
- Cardiovascular experience is preferred, but not required
- Must have experience with CRO oversight of data management activities for Ph III studies
TRAVEL & LOCATION
- None, 100% fully remote/home-based
- There is a preference for people who are local to the Princeton, NJ or San Francisco, CA locations
START & TERM
- Start immediately following thorough screening and interview and background check – late April
- 1-year contract (could easily extend)
RATE
Competitive compensation
“Skills, experience, and other compensable factors will be taken into account when determining pay rate. The pay range provided in this posting is a reflection of a W2 hourly rate; other employment options may be available that may result in pay outside of the provided range.”
“W2 employees of Eliassen Group who are regularly scheduled to work 30 or more hours per week are eligible for the following benefits: medical (choice of 3 plans), dental, vision, pre-tax accounts, other voluntary benefits including life and disability insurance, 401(k) with match, and sick time if required by law in the worked-in state/locality.”
How to Get Visa Sponsorship as a Data Manager
Lead with your degree-to-role alignment
Employers filing H-1B petitions must prove the role is a specialty occupation. A Data Manager with a degree in computer science, information systems, or statistics makes that case cleanly. Highlight your field of study prominently in every application.
Target industries with established sponsorship pipelines
Healthcare systems, financial institutions, and enterprise tech companies sponsor Data Managers consistently. These employers have existing immigration counsel and understand the LCA and H-1B filing process, which shortens timelines and reduces the chance of a first-time sponsorship refusal.
Clarify scope early in interviews
Data Manager titles vary widely. Some roles are purely operational; others involve architecture and governance. Roles with specialized technical scope, such as overseeing data pipelines or compliance frameworks, are easier to classify as specialty occupations for visa petition purposes.
Prepare documentation on your data systems expertise
USCIS scrutinizes H-1B petitions for roles where the degree requirement is not obvious. Having specific tools, certifications, or methodologies documented, such as SQL, Python, or data governance frameworks, strengthens the specialty occupation argument in your employer's petition.
Understand the LCA before your offer is finalized
Your employer files a Labor Condition Application with the Department of Labor before submitting your H-1B petition. The LCA certifies the role's prevailing wage tier. Knowing this step exists helps you set realistic timelines and confirm your employer is prepared to proceed.
O-1B is worth exploring if you have a strong portfolio
Data Managers with published research, conference presentations, or recognition for large-scale data projects may qualify for the O-1A visa. It has no lottery and no annual cap, making it a viable alternative if you miss the H-1B selection cycle.
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Get Access To All JobsFrequently Asked Questions
Does a Data Manager role qualify as an H-1B specialty occupation?
Most Data Manager positions qualify, but the title alone isn't enough. USCIS evaluates whether the role normally requires a bachelor's degree or higher in a specific field. Roles involving database architecture, data governance, or compliance frameworks qualify more cleanly than generalist coordination positions where any degree satisfies the requirement. Your employer's job description and internal classification matter significantly.
What degree do I need for H-1B sponsorship as a Data Manager?
A bachelor's degree in computer science, information systems, data science, statistics, or a closely related field is the standard baseline. Degrees in business or management are harder to use unless the role has a clear technical focus. If your degree is in an unrelated field, relevant experience and certifications can supplement it, but the petition becomes more complex and USCIS scrutiny increases.
How likely is H-1B approval for a Data Manager?
Approval rates for technology and data-related H-1B petitions run above 85% once selected in the lottery, according to USCIS data. The bigger hurdle is lottery selection itself, where roughly one in four registrations is chosen. If you miss the lottery, cap-exempt employers, including universities, nonprofit research organizations, and certain government contractors, can sponsor outside the annual cap.
How do I find employers who sponsor Data Manager roles?
Migrate Mate lists Data Manager positions from employers who have confirmed sponsorship willingness, which cuts out the guesswork of cold-applying and discovering late in the process that a company won't sponsor. Filtering by sponsorship availability is the most efficient way to focus your search, particularly if you're on OPT with a limited runway before your status requires resolution.
Can I switch employers on an H-1B as a Data Manager?
Yes. H-1B portability allows you to start working for a new employer once they file an H-1B transfer petition on your behalf, without waiting for approval. The new petition must establish that your new Data Manager role also qualifies as a specialty occupation. If the new role is significantly different in scope from the original petition, your employer's attorney may need to document the specialty occupation argument from scratch.
What is the prevailing wage requirement for sponsored Data Manager jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.
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