Director Of Program Management Jobs in USA with Visa Sponsorship
Director of Program Management roles attract H-1B visa, L-1A, and O-1 visa sponsorship from large tech, defense, and consulting employers. Most openings require a bachelor's degree in engineering or business, and many qualify as specialty occupations under USCIS standards. For detailed occupation requirements, see the O*NET profile.
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Get Access To All JobsYour Impact at LILA
Lila Sciences is looking for an Associate Director / Director, Program Management, Life Sciences — a senior operator who will drive the planning, execution, and delivery of therapeutic programs on Lila's platform. This person will provide direct project management leadership to the internal science, engineering, and automation teams developing molecules for our partners, owning timelines, resourcing, and progress tracking across complex, multidisciplinary programs. They will also serve as a senior operational interface with our pharmaceutical and biotech partners, ensuring that deliverables, governance, and communication are running smoothly.
These programs carry significant scientific complexity and commercial stakes. This role requires someone who can drive execution across fast-moving, technically demanding programs from the inside while maintaining the partner-facing judgment and presence to keep external stakeholders informed and aligned.
What You'll Be Building
- Own end-to-end project management for active therapeutic programs, including timeline development, resource coordination, milestone tracking, and dependency management across product, science, machine learning and automation teams
- Drive day-to-day execution discipline; ensuring that internal teams have clear priorities, deliverables, and decision points, and that blockers are identified and resolved quickly
- Manage resource allocation discussions and trade-off decisions across a complex set of priorities (e.g., balancing experiments between AI model training and near-term partnership deliverables)
- Establish and maintain program-level reporting, including status updates, milestone tracking, and resource utilization views for internal leadership and external deliverables
- Proactively identify, communicate, and manage program risks, escalating appropriately and ensuring transparency with scientific and executive leadership
- Structure and facilitate effective internal program meetings, decision forums, and reviews; ensuring the right information reaches the right people at the right time
Partner-Facing Delivery
- Serve as the primary operational interface with partner organizations, coordinating joint governance, managing deliverable timelines, and driving alignment on milestones and expectations
- Translate internal program status into clear, structured updates for external partners, ensuring transparency without overexposing internal complexity
- Support alliance obligations including joint steering committees, milestone reporting, and deliverable handoffs
- Partner closely with scientific and product leadership to ensure that program plans reflect both Lila's platform capabilities and partner-specific program goals and business objectives
Process & Scale
- Lead the development of scalable project management practices, templates, and tools as Lila's partnership portfolio grows
- Help build repeatable operating models for how Lila plans, tracks, and delivers partner programs
What You'll Need to Succeed
- 8+ years of experience in the pharmaceutical or biotechnology industry in roles associated with drug discovery or development, project management, or operations
- 5+ years in program management, project management, or a similar cross-functional coordination role with direct responsibility for timelines, resourcing, and tracking
- Demonstrated ability to independently drive execution across complex, multidisciplinary programs with significant scientific and commercial stakes
- Strong understanding of drug discovery and development processes; ability to engage credibly with scientific stakeholders and communicate at a high level across therapeutic and technical domains
- Experience managing programs with external partners, including milestone management, governance, and stakeholder communication
- Outstanding communication skills, with the ability to distill complex scientific and operational information for diverse audiences including executive leadership and external partners
- Proven ability to influence without authority and drive alignment across cross-functional teams
Bonus Points For
- Experience working at or partnering with AI-native or platform-based drug discovery companies
- Experience managing external collaborations in a discovery or preclinical setting (alliance management, CRO/CDMO oversight, or joint research programs)
- Familiarity with project management tools and methodologies (e.g., critical path analysis, scenario planning, resource management, portfolio reporting)
- Familiarity with the rapid evolution of LLMs and AI-driven science platforms and a perspective on how this will impact partnership models in drug discovery
About LILA
Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
We're All In
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
A Note to Agencies
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.
Your Impact at LILA
Lila Sciences is looking for an Associate Director / Director, Program Management, Life Sciences — a senior operator who will drive the planning, execution, and delivery of therapeutic programs on Lila's platform. This person will provide direct project management leadership to the internal science, engineering, and automation teams developing molecules for our partners, owning timelines, resourcing, and progress tracking across complex, multidisciplinary programs. They will also serve as a senior operational interface with our pharmaceutical and biotech partners, ensuring that deliverables, governance, and communication are running smoothly.
These programs carry significant scientific complexity and commercial stakes. This role requires someone who can drive execution across fast-moving, technically demanding programs from the inside while maintaining the partner-facing judgment and presence to keep external stakeholders informed and aligned.
What You'll Be Building
- Own end-to-end project management for active therapeutic programs, including timeline development, resource coordination, milestone tracking, and dependency management across product, science, machine learning and automation teams
- Drive day-to-day execution discipline; ensuring that internal teams have clear priorities, deliverables, and decision points, and that blockers are identified and resolved quickly
- Manage resource allocation discussions and trade-off decisions across a complex set of priorities (e.g., balancing experiments between AI model training and near-term partnership deliverables)
- Establish and maintain program-level reporting, including status updates, milestone tracking, and resource utilization views for internal leadership and external deliverables
- Proactively identify, communicate, and manage program risks, escalating appropriately and ensuring transparency with scientific and executive leadership
- Structure and facilitate effective internal program meetings, decision forums, and reviews; ensuring the right information reaches the right people at the right time
Partner-Facing Delivery
- Serve as the primary operational interface with partner organizations, coordinating joint governance, managing deliverable timelines, and driving alignment on milestones and expectations
- Translate internal program status into clear, structured updates for external partners, ensuring transparency without overexposing internal complexity
- Support alliance obligations including joint steering committees, milestone reporting, and deliverable handoffs
- Partner closely with scientific and product leadership to ensure that program plans reflect both Lila's platform capabilities and partner-specific program goals and business objectives
Process & Scale
- Lead the development of scalable project management practices, templates, and tools as Lila's partnership portfolio grows
- Help build repeatable operating models for how Lila plans, tracks, and delivers partner programs
What You'll Need to Succeed
- 8+ years of experience in the pharmaceutical or biotechnology industry in roles associated with drug discovery or development, project management, or operations
- 5+ years in program management, project management, or a similar cross-functional coordination role with direct responsibility for timelines, resourcing, and tracking
- Demonstrated ability to independently drive execution across complex, multidisciplinary programs with significant scientific and commercial stakes
- Strong understanding of drug discovery and development processes; ability to engage credibly with scientific stakeholders and communicate at a high level across therapeutic and technical domains
- Experience managing programs with external partners, including milestone management, governance, and stakeholder communication
- Outstanding communication skills, with the ability to distill complex scientific and operational information for diverse audiences including executive leadership and external partners
- Proven ability to influence without authority and drive alignment across cross-functional teams
Bonus Points For
- Experience working at or partnering with AI-native or platform-based drug discovery companies
- Experience managing external collaborations in a discovery or preclinical setting (alliance management, CRO/CDMO oversight, or joint research programs)
- Familiarity with project management tools and methodologies (e.g., critical path analysis, scenario planning, resource management, portfolio reporting)
- Familiarity with the rapid evolution of LLMs and AI-driven science platforms and a perspective on how this will impact partnership models in drug discovery
About LILA
Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
We're All In
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
A Note to Agencies
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.
See all 2,319+ Director Of Program Management jobs
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Get Access To All JobsTips for Finding Director Of Program Management Jobs
Target employers with established sponsorship programs
Large technology and defense contractors file hundreds of H-1B petitions annually. Focusing on companies with a documented sponsorship history significantly reduces the risk of an offer falling through during the visa process.
Document your specialty occupation case thoroughly
USCIS scrutinizes senior management roles for specialty occupation eligibility. Compile job descriptions, org charts, and evidence that the role requires a degree in a specific discipline, not just any bachelor's degree.
Understand how cap-exempt employers expand your options
Universities, nonprofit research institutions, and government-affiliated organizations are exempt from the H-1B annual cap. Program directors at these organizations can receive H-1B approval at any time of year without lottery exposure.
Use your management scope to strengthen an L-1A case
If you're transferring from an overseas office of a multinational company, L-1A intracompany transferee status may be faster than H-1B. Document direct reports, budget authority, and policy-setting responsibilities to support the managerial classification.
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Find Director Of Program Management JobsFrequently Asked Questions
Do Director of Program Management roles qualify as H-1B specialty occupations?
Most do, but USCIS evaluates each petition individually. The role must normally require a bachelor's degree or higher in a specific field such as engineering, computer science, or business management. Generic management titles without a defined degree requirement can draw a Request for Evidence. Providing detailed job descriptions and internal organizational context strengthens the petition considerably.
Which visa types are most common for sponsoring Director of Program Management positions?
H-1B is the most common path for new hires. L-1A is frequently used for internal transfers from multinational employers, and it has the added benefit of being a direct pathway to the EB-1C green card. O-1A is an option for directors with documented industry recognition, published work, or awards. The right choice depends on your immigration history, employer structure, and long-term goals.
Is a master's degree required to get sponsorship for this role?
No. A bachelor's degree in a relevant field such as engineering, operations, or business is typically sufficient to meet H-1B specialty occupation requirements. However, a master's degree can help if the degree field doesn't perfectly align with the job description. It also qualifies you for the U.S. advanced degree exemption, which improves H-1B lottery selection odds meaningfully.
How competitive is H-1B approval for senior program management roles?
Approval rates for Director-level program management petitions are generally strong when the employer files a well-documented petition with a clear specialty occupation argument. The main risk is at the lottery stage, not adjudication. Cap-exempt employers eliminate lottery exposure entirely. You can browse Director of Program Management roles with verified sponsorship on Migrate Mate to identify employers with strong filing track records.
Can I switch employers on an H-1B while in a Director of Program Management role?
Yes. H-1B portability allows you to start working for a new employer as soon as they file a transfer petition, without waiting for approval, as long as your current H-1B is valid and you've maintained status. The new employer files a fresh I-129. Salary, title, and job duties don't need to be identical, but the role must still qualify as a specialty occupation.
What is the prevailing wage requirement for sponsored Director Of Program Management jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.
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